Laboratory News and Research

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Cryo-EM reveals structural dynamics of RNAP-DNA interactions during transcription initiation

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription bubble, so that one exposed DNA strand can be copied into a complementary RNA strand.

10 Jul 2024

Exploring the benefits of miniaturizing NGS library preparation

In this interview, Huw Rees, a field application scientist at SPT Labtech, discusses the benefits of miniaturization in NGS library preparation and how using mosquito® can give you more value for your money.

From SPT Labtech 10 Jul 2024

KNAUER’s top-selling HPLC systems now ACT Ecolabel certified

The environmental impact of KNAUER's top-selling HPLC systems has now been evaluated by My Green Lab with the assignment of its ACT Ecolabel.

10 Jul 2024

Tirzepatide outperforms semaglutide in weight loss for overweight and obese adults

Tirzepatide leads to significantly greater weight loss than semaglutide in overweight or obese adults, with no significant difference in gastrointestinal adverse effects.

10 Jul 2024

Novel device uses a simple blood test to detect early stage lung cancer

University of Queensland researchers have designed a device that uses a simple blood test to detect early stage lung cancer.

10 Jul 2024

Bovine H5N1 flu virus in cow milk poses significant health risks, study shows

Study characterizes the pathogenicity and transmission dynamics of the H5N1 influenza virus in bovine milk, highlighting significant public health risks and potential mammalian transmission.

10 Jul 2024

Pregnancy loss risk heightened by family history of endocrine diseases

Women who have close family members with endocrine diseases, including type 2 diabetes, thyroid diseases and polycystic ovary syndrome (PCOS), are at higher risk of pregnancy loss, a new study has found.

9 Jul 2024

Study examines the frequency and preventability of adverse drug events in outpatient settings

Rachel L. Wasserman, PharmD, of the Department of General Internal Medicine at Brigham and Women's Hospital, is the lead author and David W. Bates, MD, medical director of Clinical and Quality Analysis for Mass General Brigham and Co-Director of the Center for Artificial Intelligence and BioInformatics for Mass General Brigham, is the senior author of a new study published in BMJ Quality & Safety, "Frequency and preventability of adverse drug events in the outpatient setting."

9 Jul 2024

New platform developed to probe the function of genes involved in metabolism

A multidisciplinary research team has developed a discovery platform to probe the function of genes involved in metabolism -; the sum of all life-sustaining chemical reactions.

9 Jul 2024

Cow's milk may spread H5N1 flu, but airborne transmission is limited

While H5N1 avian influenza virus taken from infected cow's milk makes mice and ferrets sick when dripped into their noses, airborne transmission of the virus between ferrets -; a common model for human transmission -; appears to be limited.

9 Jul 2024

INTEGRA Biosciences’ pipettes help to cultivate success in agriculture

The National Agricultural Research and Development Institute (NARDI) in Fundulea, Romania, relies on electronic multichannel pipettes from INTEGRA Biosciences to streamline its liquid handling workflows.

From INTEGRA Biosciences 9 Jul 2024

Revolutionary 3D imaging model enhances IVF blastocyst selection

Innovative research, presented today at the ESHRE 40th Annual Meeting in Amsterdam, has introduced a novel 3D imaging model designed to identify features of blastocysts – the early stage of development for an implanted embryo – associated with successful pregnancies.

8 Jul 2024

Study reveals social disparities in achieving live births following ART treatment

Novel research, presented today at the ESHRE 40th Annual Meeting in Amsterdam, reveals significant social disparities in achieving live births following assisted reproductive technology (ART) treatment.

8 Jul 2024

GLP-1 drugs found to lower cancer risk in diabetes patients

Research finds that GLP-1 receptor agonists significantly reduce the risk of 10 out of 13 obesity-associated cancers in type 2 diabetes patients compared to insulins, but show varied results against metformin.

8 Jul 2024

Algorithm could identify drug-resistant bacteria from microscopy images

Artificial intelligence (AI) could be used to identify drug resistant infections, significantly reducing the time taken for a correct diagnosis, Cambridge researchers have shown.

8 Jul 2024

Non-invasive saliva test could identify children missing tetanus immunity

University of Birmingham experts are developing a non-invasive saliva test that - within 15 minutes - might identify children across the Global South missing immunity to tetanus who may also have missed out on essential vaccines.

8 Jul 2024

NIH funds AI chatbot project for personalized depression treatment in Black and African Americans

As a leader in innovative health solutions, George Mason University's College of Public Health received a National Institutes of Health (NIH) AIM-AHEAD program grant to pilot an artificial intelligence (AI) chatbot for Black and African Americans with depression.

8 Jul 2024

Maternal morbidity and pregnancy risks higher for gestational carriers

Gestational carriers, also known as surrogates, experience an elevated risk of severe maternal morbidity and adverse pregnancy outcomes compared to women who conceive naturally or through in vitro fertilization (IVF), according to new research presented today at the ESHRE 40th Annual Meeting in Amsterdam.

8 Jul 2024

WHO launches an online platform for information on medical devices

World Health Organization (WHO) has introduced an online platform called MeDevIS (Medical Devices Information System), the first global open access clearing house for information on medical devices.

8 Jul 2024

Blocking IL-6 in the brain to treat cancer cachexia

Cancer is insidious. Throughout tumor progression, the disease hijacks otherwise healthy biological processes-;like the body's immune response-;to grow and spread.

8 Jul 2024