Leukemia News and Research

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Leukemia (Leukaemia) is a cancer of the blood cells. It is the most common type of blood cancer and affects 10 times as many adults as children. Most people diagnosed with leukemia are over 50 years old. No one knows why some people develop leukemia and others do not. However, scientists have identified some risk factors for the disease. Most people who have known risk factors do not get leukemia, while many who do get the disease have none of these risk factors. During the early stages of leukemia, there may be no symptoms. Many of the symptoms of leukemia don't become apparent until a large number of normal blood cells are crowded out by leukemia cells.

St. Jude projects 90 percent cure rate for acute lymphoblastic leukemia

The cure rate for the once almost universally fatal childhood cancer acute lymphoblastic leukemia (ALL) could reach 90 percent in the near future, thanks to improvements in diagnosis and treatment over the past four decades, according to investigators at St. Jude Children's Research Hospital.

11 Jan 2006

Thalomid gives hope for blood cancer sufferers

Drug company Celgene says it has halted a pivotal-stage trial of its Thalomid drug earlier than expected after the drug was shown to dramatically limit the progress of the blood cancer multiple myeloma.

9 Jan 2006

Genome discovery may prevent leukaemia

An international consortium has cracked the gene code behind a key family of fungi, which includes both the leading cause of death in leukaemia and bone marrow transplant patients and an essential ingredient of soy sauce.

From The University of Manchester 22 Dec 2005

The role of genes in the development of non-Hodgkin's lymphomas

An international consortium of epidemilogists - including Dr. Alexandra Nieters and Professor Nikolaus Becker of the Clinical Epidemiology Division of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) - has conducted the first ever investigation of genetic factors in the development of non-Hodgkin’s lymphoma (NHL) in a study called InterLymph.

15 Dec 2005

Gene mapping project promises new targeted cancer therapies

Government researchers in the United States have this week launched a pilot project to find all the little genetic changes that cause cancer in the hope it will lead to a whole new world of targeted cancer therapy.

14 Dec 2005

AMN107 drug shows promise in leukemia resistance to Gleevec

The targeted agent AMN107 can produce dramatic benefits in patients with some forms of leukemia that are resistant to Gleevec, the standard therapy for these cancers, say researchers at The University of Texas M. D. Anderson Cancer Center.

13 Dec 2005

Common baby illnesses may trigger cancer

Researchers in the UK say that the common infections that affect mothers and babies may trigger certain types of childhood cancers.

12 Dec 2005

Common garden plant may hold cure for leukemia

Scientists in the U.S. believe they have identified a new pathway in the progression of chronic myelogenous leukemia (CML).

12 Dec 2005

Infections are a major cause of childhood cancer

Results from a new study of childhood cancer statistics provide further evidence that common infections affecting mother and baby could play a key role in triggering certain types of the disease.

12 Dec 2005

Stem cells may cause some forms of bone cancer

The researchers are the first to identify a population of cells with characteristics of adult and embryonic stem cells in cultures derived from biopsies of patients' bone tumors. They describe their findings in the medical journal Neoplasia.

7 Dec 2005

Cancer cell resistance to chemotherapy drugs - mechanism discovered

Technion-Israel Institute of Technology researchers have discovered new mechanisms developed by cancer cells to become resistant to various chemotherapy drugs.

6 Dec 2005

LEDGF protein controls the location of HIV integration in human cells

A human DNA-associated protein called LEDGF is the first such molecule found to control the location of HIV integration in human cells, according to researchers at the University of Pennsylvania School of Medicine.

5 Dec 2005

Researchers link microRNA - miR 196 - to limb development

A tiny strand of molecules plays a role in how our arms and legs develop and grow - a finding that sheds light on perplexing bits of material once dismissed as genetic "junk," say scientists at the University of Florida and Harvard University.

5 Dec 2005

Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease

Scientists at the Johns Hopkins Kimmel Cancer Center have found that a gene pathway linked to a deadly form of leukemia may provide a new way to treat autoimmune diseases, including multiple sclerosis.

2 Dec 2005

Master switch for blood cell development detected

Blood cells develop from blood stem cells in the bone marrow. Their development is regulated by roughly 20 gene regulators or transcription factors.

28 Nov 2005

Plant extract forskolin may lead to leukemia treatment

Scientists here have identified a new pathway in the progression of chronic myelogenous leukemia (CML). They also discovered that an extract from the root of a common ornamental plant can suppress the process.

20 Nov 2005

FLT-1 blockers, cutting the legs of leukaemia

Leukaemia is characterised by an uncontrolled growth of abnormal blood cells in the bone marrow (BM).

14 Nov 2005

Gene doping is a real danger - but anti-doping science is making progress

Gene therapy research has reached a critical phase. Already practised on humans as part of strictly controlled experiments, gene therapy promises to become a widely available form of treatment for injury and disease.

7 Nov 2005

Gene fusion appears to cause prostate cancer

Scientists at the University of Michigan Medical School, in collaboration with researchers at Harvard's Brigham and Women's Hospital, have discovered a recurring pattern of scrambled chromosomes and abnormal gene activity that occurs only in prostate cancer.

30 Oct 2005

Menin is a key player in the development of some forms of acute leukemia

Tumor-suppressor proteins work to inhibit tumor growth in our bodies and when they win, they spare us a battle with cancer. But one such protein, menin, appears to have a split personality.

20 Oct 2005