Leukocyte News and Research

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Combination of salmeterol and fluticasone propionate cuts inflammatory cells in chronic obstructive pulmonary disease

The combination of two existing clinical treatments, salmeterol and fluticasone propionate, can significantly reduce inflammatory cells in the airways of current and former smokers being treated for moderate to severe chronic obstructive pulmonary disease (COPD).

4 Apr 2006

Scientists identify a new gene that causes the spread of cancer

Professor Philip Rudland, Dr Guozheng Wang and Dr Roger Barraclough from the University’s Cancer and Polio Research Fund Laboratories have discovered an additional member of the S100 family of protein genes - S100P - that causes the spread of cancerous cells from an original tumour to other parts of the body.

30 Mar 2006

Study provides a boost for efforts to reverse type-1 diabetes

Researchers have been able to confirm most but not all of the results of a high-profile study that brought new hope to diabetes patients. This study provides a boost for efforts to reverse type-1 diabetes in recently diagnosed patients but not for efforts to grow new islets from spleens.

27 Mar 2006

First evidence that dendritic cells show unprecedented sensitivity to thimerosal

A team of cell biologists, toxicologists and molecular bioscientists at UC Davis has published a study connecting thimerosal with disruptions in antigen-presenting cells known as dendritic cells obtained from mice.

22 Mar 2006

A newly recognized type of immune cell may play an important role in causing asthma

...perhaps explaining why current therapies sometimes fail, report researchers from Children's Hospital Boston in the New England Journal of Medicine.

21 Mar 2006

Study to Rituximab's potential to preserve insulin production in newly diagnosed type 1 diabetics

A drug used to treat lymphoma, rheumatoid arthritis and other immune disorders may enable newly-diagnosed type 1 diabetics to save some of their pancreas function and thereby reduce their susceptibility to long-term complications.

20 Mar 2006

Inefficient cytotoxic T lymphocyte mediated killing of HIV-1 infected cells in vivo

HIV attacks the immune system by infecting and killing helper T lymphocytes (also called CD4 T cells), the white blood cells responsible for mobilizing the mediators of an immune response.

15 Mar 2006

Study recommends treatment change for pre-leukemia disease

A new study finds that longer courses of a mild form of chemotherapy may help patients with a bone marrow disease only recently considered a form of cancer.

14 Mar 2006

Decitabine improves myelodysplastic syndrome treatment

A potent member of a new class of drugs increases survival in some patients with myelodysplastic syndrome (MDS), and may become the new standard of therapy for this group of pre-cancer disorders

14 Mar 2006

Decitabine improves patient outcomes in myelodysplastic syndromes

Decitabine, a new drug undergoing Phase III efficacy trials, provides palliative therapy for patients with the bone marrow disease called Myelodysplastic Syndrome (MDS), according to a new study.

14 Mar 2006

Using a growth factor to stimulate production of circulating endothelial progenitor cells improves cell production and mobility in arterial disease

Using a growth factor to stimulate production of circulating endothelial progenitor cells increases the numbers of these vascular regenerative cells, improves mobility, and potentially could improve blood vessel function in patients with peripheral arterial disease (PAD).

13 Mar 2006

Thalidomide improves remission in myeloma

Myeloma is one of the least curable cancers and involves plasma cells, the white blood cells that produce antibodies.

9 Mar 2006

Scientists fight leukaemia with 'natural killer' cells

Scientists at the University of the West of England and the Bone Marrow Transplant Unit at the Bristol Children's Hospital have just won funding for a two-year project aimed at improving the outcome of bone marrow stem-cell transplants in young leukaemia patients.

8 Mar 2006

Swedish theory suggests treatment for Avian Influenza Infection

Chemotherapy for a disorder of the immune system may - at least in theory - be effective against severe human avian influenza infection, this suggest scientists at the Karolinska Institutet.

8 Mar 2006

Topical therapies show promise for Psoriasis

Psoriasis, a chronic skin condition characterized by thick, red, scaly patches that itch and bleed, not only makes the activities of daily life difficult, but also can affect a person's emotional well being.

6 Mar 2006

Defective apoptosis of dendritic cells can be a critical component of autoimmune diseases

The failure of programming that sparks the death of dendritic cells - those that activate the immune system - can initiate autoimmune disease, said researchers from Baylor College of Medicine in a report that appears in the current issue of the journal Science.

1 Mar 2006

Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer

A new study shows that patients whose colorectal cancer has spread to the liver who received an approach called hepatic arterial infusion (HAI) - the administration of chemotherapy directly to the liver through a pump in the abdomen - fare better than those who received traditional, intravenous chemotherapy.

1 Mar 2006

Why people of African descent are more vulnerable to tuberculosis infection

A team of scientists has identified a cellular mechanism that may help explain the puzzle of why people of African descent are more susceptible to tuberculosis infection and why, once infected, they develop more severe states of the disease than whites.

27 Feb 2006

Combination therapy improves Acquired Immunodeficiency Syndrome-Related Lymphoma outcome

Combining aggressive HIV therapy and chemotherapy significantly improves the survival rates of HIV-positive men and women treated for lymphoma, according to a new study.

27 Feb 2006

Viagra could cure Crohn's disease

Crohn's disease is a chronic inflammatory bowel disorder which causes ulcerations in the gut and can make digesting food painful.

27 Feb 2006

Leukocyte News and Research

Combination of salmeterol and fluticasone propionate cuts inflammatory cells in chronic obstructive pulmonary disease

Scientists identify a new gene that causes the spread of cancer

Study provides a boost for efforts to reverse type-1 diabetes

First evidence that dendritic cells show unprecedented sensitivity to thimerosal

A newly recognized type of immune cell may play an important role in causing asthma

Study to Rituximab's potential to preserve insulin production in newly diagnosed type 1 diabetics

Inefficient cytotoxic T lymphocyte mediated killing of HIV-1 infected cells in vivo

Study recommends treatment change for pre-leukemia disease

Decitabine improves myelodysplastic syndrome treatment

Decitabine improves patient outcomes in myelodysplastic syndromes

Using a growth factor to stimulate production of circulating endothelial progenitor cells improves cell production and mobility in arterial disease

Thalidomide improves remission in myeloma

Scientists fight leukaemia with 'natural killer' cells

Swedish theory suggests treatment for Avian Influenza Infection

Topical therapies show promise for Psoriasis

Defective apoptosis of dendritic cells can be a critical component of autoimmune diseases

Hepatic arterial infusion versus systemic therapy for hepatic metastases from colorectal cancer

Why people of African descent are more vulnerable to tuberculosis infection

Combination therapy improves Acquired Immunodeficiency Syndrome-Related Lymphoma outcome

Viagra could cure Crohn's disease

Immunology eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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