Lewy Bodies News and Research

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SynNeurGe: A new biological classification system for Parkinson's disease research

One of the things that makes developing effective treatments for Parkinson's disease so challenging is its complexity.

23 Jan 2024

Protein linked to neurodegeneration turns out to be crucial for healthy brain function

Researchers have discovered that a protein called phosphorylated α-synuclein, which is associated with several neurodegenerative diseases such as Parkinson's disease and Lewy body dementia, is also involved in the normal processes of how neurons communicate with each other in a healthy brain.

9 Jan 2024

New test detects Parkinson's disease before symptoms appear

In the development of Parkinson's disease (PD), the changes that will lead to neurodegeneration take place in the brain long before patients show any symptoms.

8 Jan 2024

NEMO protein's crucial role in Parkinson's defense revealed

Researchers have identified a mechanism that promotes the breakdown of harmful protein deposits. If it malfunctions, it can lead to Parkinson’s disease.

19 Dec 2023

Parkinson's disease a potential pathogenetic factor for coronary artery disease and stroke, study suggests

Researchers performed a two-sample Mendelian randomization (MR) analysis to explore causal associations between Parkinson's disease (PD) and cardio-cerebrovascular diseases.

24 Nov 2023

$3.9 million NIH grant supports research on the Effects of integrated palliative care on Parkinson’s, related dementia

A five-year, $3.9 million grant to study the effects of integrated palliative care on health service outcomes and disparities in Parkinson's disease and Parkinson's disease dementia has been awarded to UTHealth Houston and other institutions by the National Institute of Neurological Disorders and Stroke, part of the National Institutes of Health.

15 Nov 2023

Pharmacogenomics holds promise for personalized dementia therapies

Pharmacogenomics-based studies in the research for personalized therapeutics for dementia

8 Nov 2023

PET scans of the heart identify people at risk for Parkinson's and Lewy body dementia

In a small study, researchers at the National Institutes of Health have found that positron emission tomography (PET) scans of the heart may identify people who will go on to develop Parkinson's disease or Lewy body dementia among those at-risk for these diseases.

7 Nov 2023

Cutting-edge NanoSIMS imaging sheds light on the progression of Parkinson's disease

Parkinson's disease is a complex neurodegenerative disorder that leads to the deterioration of specific types of neurons in the brain, resulting in a number of motor and non-motor symptoms.

29 Sep 2023

Zebrafish model could help unlock Parkinson's disease mechanisms

Nearly one million people in the United States are living with Parkinson's disease, making it the second-most common neurodegenerative disease after Alzheimer's.

21 Aug 2023

The role of self-extracellular nucleic acids in neuroinflammation

Researchers explore the role of self-extracellular nucleic acids in diseases like stroke, multiple sclerosis, Alzheimer’s disease, and Parkinson’s disease.

14 Aug 2023

Study detects biomarker changes nearly 30 years before symptom onset of Alzheimer’s disease

A new paper has shown how Alzheimer’s disease pathology comes into being over a period of almost three decades.

10 Aug 2023

Sense of smell may hold clues to Lewy body pathology: new evidence emerges

Researchers evaluated the impact of Lewy body (LB) positivity (+) on clinical outcomes such as cognition and smell among cognitively.

20 Jul 2023

Spinal fluid test could be used for early detection of Lewy body disease

Lewy body disease is the second most common neurodegenerative disease after Alzheimer's disease. A research group from Lund University has now shown that the disease can be detected before symptoms appear, using a spinal fluid test.

18 Jul 2023

New proteomic insights: cerebrospinal fluid biomarkers show promise in detecting dementia with Lewy bodies

Researchers conducted cerebrospinal fluid (CSF) proteome profiling and identified CSF proteins.

17 Jul 2023

Early hallucinations may indicate faster cognitive decline in patients with Parkinson's disease

Have you ever felt the strong sensation that someone is behind you, so intense that you turn around, only to see that no-one is there? This is a 'presence hallucination'.

29 Jun 2023

Alarming rise: New cases of dementia surging in elderly population of Wales, UK

Dementia cases are increasing among the elderly population, with a rise in new diagnoses and a growing number of people living with the disease. This trend poses challenges for healthcare systems as the aging population with dementia continues to grow.

20 Jun 2023

Novel assay for identifying individuals with synucleinopathies using serum samples

Synucleinopathies are a group of neurodegenerative diseases caused by the abnormal accumulation α-synuclein, a protein normally found in the brain and neurons. Incorrect folding of α-synuclein leads to formation of 'seeds', which attract more α-synuclein proteins to form larger clumps.

29 May 2023

Study uncovers a protein-protein interaction that contributes to Parkinson's disease

In a study published in Nature Communications, a team led by Krembil Brain Institute Senior Scientists, Drs. Lorraine Kalia and Suneil Kalia, and University of Toronto (U of T) Professor, Dr. Philip M. Kim, identified a protein-protein interaction that contributes to Parkinson's disease.

20 Apr 2023

Did COVID-19-associated lockdowns increase the rate of memory decline in patients with cognitive impairments?

Researchers investigated whether COVID-19-associated lockdown measures had an impact on the cognitive decline rate.

18 Apr 2023