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Creoptix launches new WAVEcontrol software to deliver automated, flexible and intuitive label-free interaction analysis for biologics drug-discovery

Creoptix® (a Malvern Panalytical brand) is announcing the addition of two new wizards to their WAVEcontrol software to simplify and streamline workflows. By combining the high sensitivity, throughput, and no-clog microfluidics of the WAVEsystem, with a faster, more flexible, automated approach to screening and characterization, Creoptix is accelerating biologics drug discovery and diagnostics development.

From Malvern Panalytical 7 Sep 2022

Study suggests loss of smell and brain inflammation are independent in COVID-19

Researchers assessed the association between neuroinvasion and anosmia observed during COVID-19.

5 Sep 2022

Using AI to foster productivity in pharmaceutical research and development

As part of our SLAS Europe 2022 coverage, we speak to Sree Vadlamudi from Iktos, about how we can adopt AI to help foster productivity within pharmaceutical research.

From Society for Laboratory Automation and Screening (SLAS) 25 Aug 2022

Virtual screening and molecular dynamics explore potential repurposed drugs against monkeypox virus

A recent study investigated ‘targets’ in the poxvirus and identified the protein residues active in MPV, following which eight potential anti-viral drugs were proposed.

25 Aug 2022

Researchers identify a potential new therapeutic approach to fight angioimmunoblastic T-cell lymphoma

A type of blood cell cancer called angioimmunoblastic T-cell lymphoma (AITL) can develop as mutations accumulate with age in the stem cells from which the T cells in the blood develop.

24 Aug 2022

Researchers visualize antigen-bound T-cell receptor at atomic resolution

T cells are our immune system’s customized tools for fighting infectious diseases and tumor cells. On their surface, these special white blood cells carry a receptor that recognizes antigens.

18 Aug 2022

CD98 identified as a key mediator of pro-fibrotic and acute inflammatory responses in the lung

Researchers investigated the role of the CD98 glycoprotein in inducing an inflammatory response to SARS-CoV-2 in patients of progressive fibrosis interstitial lung diseases, including the archetypal PFILD, idiopathic pulmonary fibrosis.

18 Aug 2022

Remdesivir activates urotensin II receptor and induces cardiomyocyte dysfunction

In newly released research, scientists assessed the cardiac effects of remdesivir.

12 Aug 2022

Researchers identify novel molecular pathway that suppresses the spread of glioblastoma

UT Southwestern researchers have identified a molecular pathway responsible for the spread of glioblastoma to surrounding tissue in the brain, as well as an existing drug that curbed tumor growth in animal models.

10 Aug 2022

Study suggests BA.5 evolved to induce enhanced inflammation when compared to prior Omicron subvariants

Researchers evaluated the comparative pathogenicity of SARS-CoV-2 Omicron sub-variants BA.1, BA.2, and BA.5, in vitro and in vivo.

9 Aug 2022

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

A new study revealed that the replication of the ancestral strain of SARS-CoV-2 is less efficient in nasal epithelial cells (NECs) of children.

3 Aug 2022

Experiments and mathematical modeling help study the role of morphogens in tissue patterning

Morphogens are molecules that travel from biological cell to cell to pattern tissues in the embryo. These molecules are important not only for the embryo during development, but also for the adult during tissue repair.

2 Aug 2022

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Colorectal tumors are a common adverse effect of chronic inflammation of the intestine. In a new study, researchers from Japan and China demonstrate that mice models with dendritic cell immunoreceptor (DCIR) protein deficiency are resistant to colonic tumors induced by dextran sodium sulfate and azoxymethane.

2 Aug 2022

Ligand News and Research

Creoptix launches new WAVEcontrol software to deliver automated, flexible and intuitive label-free interaction analysis for biologics drug-discovery

Study suggests loss of smell and brain inflammation are independent in COVID-19

Using AI to foster productivity in pharmaceutical research and development

Virtual screening and molecular dynamics explore potential repurposed drugs against monkeypox virus

Researchers identify a potential new therapeutic approach to fight angioimmunoblastic T-cell lymphoma

Researchers visualize antigen-bound T-cell receptor at atomic resolution

CD98 identified as a key mediator of pro-fibrotic and acute inflammatory responses in the lung

Remdesivir activates urotensin II receptor and induces cardiomyocyte dysfunction

Researchers identify novel molecular pathway that suppresses the spread of glioblastoma

Study suggests BA.5 evolved to induce enhanced inflammation when compared to prior Omicron subvariants

Less efficient replication of ancestral SARS-CoV-2 in primary nasal epithelium of children

Experiments and mathematical modeling help study the role of morphogens in tissue patterning

Research could pave the way for therapeutic strategies targeting DCIR to treat colorectal tumors

Oligomeric molecular structure of the MOR-Gal1R complex revealed

Is monkeypox a global public-health emergency?

What is the association between natural killer cell dysfunction and COVID-19 disease severity?

Scientists evaluate immunostimulatory glycolipid against SARS-CoV-2 infection

Study shows that older adults can generate robust, long-lived memory against SARS-CoV-2 following infection

Characterization of longer-term effects on behavior and brain inflammation following recovery from mild COVID-19

Discovery of multiple new SARS-CoV-2 MPro inhibitors

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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