Lipitor (Atorvastatin) News and Research

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Atorvastatin (INN) (Lipitor, Pfizer), is a member of the drug class known as statins, used for lowering blood cholesterol. It also stabilizes plaque and prevents strokes through anti-inflammatory and other mechanisms. Atorvastatin inhibits HMG-CoA reductase, the rate-determining enzyme located in hepatic tissue that produces mevalonate, a small molecule used in the synthesis of cholesterol and other mevalonate derivatives. This lowers the amount of cholesterol produced which in turn lowers the total amount of LDL cholesterol. Atorvastatin was first synthesized in 1985 by Bruce Roth while working at Parke-Davis Warner-Lambert Company (now Pfizer). With 2006 sales of US$12.9 billion, Lipitor is the largest-selling drug in the world.

Cholesterol-lowering statin products may be the next class of drugs to go over the counter

Cholesterol-lowering statin products may be the next class of drugs to go over the counter (OTC), according to "Cardiovascular Marketing," a new study by business intelligence firm Cutting Edge Information.

28 Apr 2004

New ways to fight type 2 diabetes

Adults with type 2 diabetes who have just one additional risk factor for heart disease should be taking medication to lower cholesterol levels, according to new guidelines from the American College of Physicians (ACP).

19 Apr 2004

Liptor helps Alzheimer’s disease

In a small clinical trial enrolling 63 individuals with Alzheimer’s disease, half of those who received atorvastatin (Lipitor) stabilized or improved after one year of treatment, the trial’s principal investigator D. Larry Sparks, Ph.D., reported today at a professional meeting on Alzheimer therapy.

15 Apr 2004

'Medicare-Approved' cards available soon

Beginning in June 2004, the Medicare discount card program will provide America's seniors and disabled Medicare beneficiaries with much-needed discounts and information on their prescription drugs. The purchasing power behind the Medicare population is expected to save beneficiaries an average of 10 to 25 percent off the retail price of most drugs.

14 Apr 2004

Pfizer's files lawsuit against unapproved copy of cholesterol drug Lipitor

Pfizer announced that it has filed a lawsuit against the operator of "look4generics.com," an internet site selling an unapproved copy of Pfizer's cholesterol drug, Lipitor. The suit was filed today in U.S. District Court in Delaware.

12 Apr 2004

Medicare to launch website showing comparative drug pricing

Medicare has announced it will be publishishing detailed information comparing the prices of most prescription drugs, which is set to shake up the pharmaceutical industry.

12 Apr 2004

Research shows that intense high dose cholesterol lowering drugs result in a major reduction in deaths and severe heart attacks

If you want to increase your chances of living longer, taking cholesterol drugs is an easy way to do it. That's the message from a Harvard study of 4,162 people hospitalized in 350 places in eight countries. It is the first research to show that intense lowering of cholesterol results in a major reduction in deaths and severe heart attacks.

7 Apr 2004

Largest marketing campaign for a single drug to date

The cardiovascular market, one of the most hotly contested therapeutic areas of the pharmaceutical industry, continues to expand. Together, drugs that lower blood pressure and cholesterol treat 303 million potential patients worldwide. Nevertheless, companies that develop fourth or fifth to market drugs will struggle to compete, according to research by business intelligence firm Cutting Edge Information.

22 Mar 2004