Liquid Chromatography News and Research

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Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

Researchers found that young bone marrow transplants rejuvenate aging immune cells, reducing Alzheimer's symptoms in mice models, suggesting a potential therapeutic approach for the disease.

4 Jun 2024

Canagliflozin enhances senescent cell clearance, improving aging-related conditions

Whether sodium-glucose co-transporter 2 (SGLT2) inhibitors induce senolysis.

3 Jun 2024

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss

A recent study in Nature Communications found that intermittent fasting with protein pacing (IF-P) is more effective than continuous calorie restriction (CR) in improving gut microbiota and metabolomic profiles, leading to greater weight and fat loss.

2 Jun 2024

Tailoring polymeric micelles for improved olaparib solubility and drug release

Olaparib is a selective poly (ADP-ribose) polymerase inhibitor. However, its clinical application is hindered by low solubility and undesired pharmacokinetic profiles (e.g., relatively short circulation).

23 May 2024

Treating obesity using glucagon-like peptide-1-directed N-methyl-D-aspartate receptor inhibition

Bimodal drug that successfully cures obesity, hyperglycemia, and dyslipidemia in mouse models.

20 May 2024

New insights into Chaga mushroom's mechanisms for fighting oral cancer

The mechanisms behind the anti-tumor activity of Chaga mushroom extracts in HSC-4 human oral cancer cells.

13 May 2024

Research validates anti-inflammatory properties of wine using urinary tartaric acid as biomarker

The anti-inflammatory effects of wine by analyzing the relationship between urinary tartaric acid concentrations and changes in serum inflammatory biomarkers.

13 May 2024

Prenatal exposure to bisphenol and phthalate linked to increased child obesity, study finds

Researchers found links between higher prenatal exposure to bisphenols and high-molecular-weight phthalates with increased child weight and BMI from birth to age four in a New York cohort study.

9 May 2024

Protein profiling reveals impact of aging and resistance training on skeletal muscle proteome

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "A novel deep proteomic approach in human skeletal muscle unveils distinct molecular signatures affected by aging and resistance training."

2 May 2024

Yokogawa helps to revolutionize the field of single-cell lipidomics

Yokogawa Electric Corporation's latest single-cell analysis solution, the Single Cellome™ System SS2000, has been featured in an article published in the high-profile journal Analytical Chemistry regarding groundbreaking work conducted by researchers at the University of Surrey in the emerging field of single-cell lipidomics.

From Yokogawa Electric Corporation 2 May 2024

Study links endocrine-disrupting chemical exposure to poorer sleep and vitamin D deficiency

Study in the journal Nutrients links exposure to endocrine-disrupting chemicals with vitamin D deficiency and reduced sleep duration, suggesting a compounded negative impact on health.

30 Apr 2024

Low vitamin D tied to belly fat and weak muscles in women

Low vitamin D in women is linked to more belly fat and lower muscle mass. The study suggests using waist-to-height ratio and muscle mass index to assess health risks.

25 Apr 2024

New system personalizes chemotherapy doses for cancer patients

When cancer patients undergo chemotherapy, the dose of most drugs is calculated based on the patient's body surface area. This is estimated by plugging the patient's height and weight into an equation, dating to 1916, that was formulated from data on just nine patients.

24 Apr 2024

New technique allows scientists to study the fatty contents of cancer cells

Imagine being able to look inside a single cancer cell and see how it communicates with its neighbors.

23 Apr 2024

New technique tracks drug use through smartphones

A simple and convenient method to collect drug use data from the surface of a smartphone is revealed for the first time in a new study published in De Gruyter's Clinical Chemistry and Laboratory Medicine. By helping clinicians understand what drugs people are taking in certain contexts, the research could protect public health and improve the treatment of patients suspected of overdosing.

23 Apr 2024

Liquid Chromatography News and Research

Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

Canagliflozin enhances senescent cell clearance, improving aging-related conditions

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss

Tailoring polymeric micelles for improved olaparib solubility and drug release

Treating obesity using glucagon-like peptide-1-directed N-methyl-D-aspartate receptor inhibition

New insights into Chaga mushroom's mechanisms for fighting oral cancer

Research validates anti-inflammatory properties of wine using urinary tartaric acid as biomarker

Prenatal exposure to bisphenol and phthalate linked to increased child obesity, study finds

Protein profiling reveals impact of aging and resistance training on skeletal muscle proteome

Yokogawa helps to revolutionize the field of single-cell lipidomics

Study links endocrine-disrupting chemical exposure to poorer sleep and vitamin D deficiency

Low vitamin D tied to belly fat and weak muscles in women

New system personalizes chemotherapy doses for cancer patients

New technique allows scientists to study the fatty contents of cancer cells

New technique tracks drug use through smartphones

Study finds high microplastic levels in Mediterranean fish despite low chemical contaminants

Exploring the benefits of blueberries: Studies link extract to reduced cognitive aging

Burdock roots outshine dandelion in antidiabetic potential study

Study highlights anti-inflammatory properties of herbal medicine, Erigeron breviscapus to treat osteoarthritis

Novel lipids in traditional herbal teas unlock potential health gains

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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