Liquid Chromatography News and Research

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Are your ‘takeaway’ coffees exceeding daily recommended levels for caffeine intake?

The caffeine content in various popular coffee servings to assess their safety regarding recommended daily intake limits.

26 Jul 2024

E-Cigarettes and Ethanol: A Forensic Perspective on Vaping

In this interview conducted at Pittcon 2024 in San Diego, we spoke to Professor Michelle Peace about the challenges and implications of detecting ethanol in e-cigarettes for drug testing and forensic toxicology.

From Pittcon 23 Jul 2024

Study investigates the link between an exposome score and metabolic health across childhood

The combined effect of environmental exposures and unhealthy lifestyle habits can affect children's cardiometabolic health in a way that exceeds their separate effects.

23 Jul 2024

Research highlights importance of dietary education to combat rising childhood obesity rates

The artificial sweetener content of children's commonly consumed food products.

18 Jul 2024

Early detection of aggressive multiple myeloma through molecular analysis

Multiple myeloma is one of the most common forms of cancer of the immune cells in the bone marrow. It is considered incurable.

1 Jul 2024

New study reveals key to more effective antihistamines

Even if two molecules have the exact same chemical formula and the same number and types of bonds, their three-dimensional arrangements can still be different.

1 Jul 2024

PFAS exposure in early life: Health risks and maternal-fetal transport mechanisms

Polyfluoroalkyl substances (PFAS) are a class of chemicals extensively used in consumer goods production due to their hydrophobic and oleophobic properties and stability.

24 Jun 2024

Proteins in blood may help to predict Parkinson’s disease up to seven years before the onset of motor symptoms

Researchers combined mass spectrometry-based proteomic phenotyping with machine learning to identify blood biomarkers in early Parkinson's disease.

20 Jun 2024

Are we using more sugar substitutes? Wastewater analysis reveals trends in Swedish cities

A study in Environment International used wastewater analysis to track artificial sweetener usage in five Swedish communities during the COVID-19 pandemic, finding no significant health risks from consumption levels.

17 Jun 2024

Proteomic profiling reveals sexual dimorphism and immune system alterations in Werner syndrome

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 10, entitled, "Integrated liver and serum proteomics uncover sexual dimorphism and alteration of several immune response proteins in an aging Werner syndrome mouse model."

4 Jun 2024

Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

Researchers found that young bone marrow transplants rejuvenate aging immune cells, reducing Alzheimer's symptoms in mice models, suggesting a potential therapeutic approach for the disease.

4 Jun 2024

Canagliflozin enhances senescent cell clearance, improving aging-related conditions

Whether sodium-glucose co-transporter 2 (SGLT2) inhibitors induce senolysis.

3 Jun 2024

Intermittent fasting with protein pacing trumps calorie restriction in gut health and weight loss

A recent study in Nature Communications found that intermittent fasting with protein pacing (IF-P) is more effective than continuous calorie restriction (CR) in improving gut microbiota and metabolomic profiles, leading to greater weight and fat loss.

2 Jun 2024

Tailoring polymeric micelles for improved olaparib solubility and drug release

Olaparib is a selective poly (ADP-ribose) polymerase inhibitor. However, its clinical application is hindered by low solubility and undesired pharmacokinetic profiles (e.g., relatively short circulation).

23 May 2024

Treating obesity using glucagon-like peptide-1-directed N-methyl-D-aspartate receptor inhibition

Bimodal drug that successfully cures obesity, hyperglycemia, and dyslipidemia in mouse models.

20 May 2024

New insights into Chaga mushroom's mechanisms for fighting oral cancer

The mechanisms behind the anti-tumor activity of Chaga mushroom extracts in HSC-4 human oral cancer cells.

13 May 2024

Research validates anti-inflammatory properties of wine using urinary tartaric acid as biomarker

The anti-inflammatory effects of wine by analyzing the relationship between urinary tartaric acid concentrations and changes in serum inflammatory biomarkers.

13 May 2024

Prenatal exposure to bisphenol and phthalate linked to increased child obesity, study finds

Researchers found links between higher prenatal exposure to bisphenols and high-molecular-weight phthalates with increased child weight and BMI from birth to age four in a New York cohort study.

9 May 2024

Protein profiling reveals impact of aging and resistance training on skeletal muscle proteome

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "A novel deep proteomic approach in human skeletal muscle unveils distinct molecular signatures affected by aging and resistance training."

2 May 2024

Yokogawa helps to revolutionize the field of single-cell lipidomics

Yokogawa Electric Corporation's latest single-cell analysis solution, the Single Cellome™ System SS2000, has been featured in an article published in the high-profile journal Analytical Chemistry regarding groundbreaking work conducted by researchers at the University of Surrey in the emerging field of single-cell lipidomics.

From Yokogawa Electric Corporation 2 May 2024