Lissencephaly News and Research

RSS
Lissencephaly, which literally means ''smooth brain'', is a rare brain formation disorder caused by defective neuronal migration during the 12th to 24th weeks of gestation, resulting in a lack of development of brain folds (gyri) and grooves (sulci).
Study reveals how cells from patients with developmental disease differ from healthy cells

Study reveals how cells from patients with developmental disease differ from healthy cells

Dmrta2 gene mutation can lead to abnormal brain development in unborn babies

Dmrta2 gene mutation can lead to abnormal brain development in unborn babies

New method combines organoid technology with bioengineering to build better brains

New method combines organoid technology with bioengineering to build better brains

Scientists use brain organoids to identify root causes of Miller-Dieker syndrome

Scientists use brain organoids to identify root causes of Miller-Dieker syndrome

New report documents fetal brain abnormalities linked to congenital Zika infection

New report documents fetal brain abnormalities linked to congenital Zika infection

New findings on microcephaly may offer clues to explore how Zika virus disrupts brain development

New findings on microcephaly may offer clues to explore how Zika virus disrupts brain development

RIKEN researchers discover how to reverse abnormal axonal development

RIKEN researchers discover how to reverse abnormal axonal development

Determining the dynein-dynactin complex structure: an interview with Dr Gabriel C. Lander

Determining the dynein-dynactin complex structure: an interview with Dr Gabriel C. Lander

Nerve cells guide each other during embryonic development

Nerve cells guide each other during embryonic development

UCSF researchers identify novel molecular features within the developing human brain

UCSF researchers identify novel molecular features within the developing human brain

Researchers discover new gene mutations associated with megalencephaly

Researchers discover new gene mutations associated with megalencephaly

Scientists identify how cell architecture changes during formation of gametes

Scientists identify how cell architecture changes during formation of gametes

ACTB and ACTG1 actin genes cause Baraitser-Winter syndrome

ACTB and ACTG1 actin genes cause Baraitser-Winter syndrome

Study unveils surprising mechanism that controls brain formation

Study unveils surprising mechanism that controls brain formation

UCSF scientists discover new stem cell in developing human brain

UCSF scientists discover new stem cell in developing human brain

Migrant neuron: New imaging studies reveal mechanics of neuron migration

Migrant neuron: New imaging studies reveal mechanics of neuron migration

Cause of severe pediatric epilepsy disorder discovered

Cause of severe pediatric epilepsy disorder discovered

Extra copies of LIS1 gene carry extra risk

Extra copies of LIS1 gene carry extra risk

Key factor in brain development revealed, offers insight into lissencephaly

Key factor in brain development revealed, offers insight into lissencephaly

N-cofilin molecule protects from neuronal disorders

N-cofilin molecule protects from neuronal disorders