Listeria News and Research

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Listeria is a bacterial genus containing seven species. Named after the English pioneer of sterile surgery, Joseph Lister, Listeria species are Gram-positive bacilli and are typified by ''L. monocytogenes'', the causative agent of listeriosis.

Good digestive health may help regulate and reduce stress in the brain

Good digestive health may help to regulate and reduce stress in the brain, according to a recent study out of University College Cork in Cork, Ireland and featured in the October issue of Food Nutrition & Science.

31 Oct 2011

New genomic approach can trace food-borne bacteria with unprecedented accuracy

With salmonella-tainted ground turkey sickening more than 100 people and listeria-contaminated cantaloupes killing 15 this year, the ability to detect outbreaks of food-borne illness and determine their sources has become a top public health priority.

27 Oct 2011

CWRU to lead Cornea Preservation Time Study

Researchers at Case Western Reserve University School of Medicine will lead a national study determining if corneas transplanted up to two weeks after donor death work as well as corneas transplanted up to one week after donor death. The National Eye Institute has awarded a $12.3 million grant to support the work.

20 Oct 2011

New treatment approach for septic Listeria infection

Research underway at the Trudeau Institute could lead to new treatments for people sickened by Listeria and other sepsis-causing bacteria. Dr. Stephen Smiley's laboratory has published a study in the scientific journal Infection and Immunity that supports a new approach to treating these infections.

18 Oct 2011

FDA grants Advaxis pre-IND meeting for ADXS-HER2 cancer immunotherapy

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, has been granted a pre-Investigational New Drug meeting with the U.S. Food and Drug Administration on November 22nd, 2011 to discuss the initial clinical development plan for ADXS-HER2, a construct for the treatment of HER2 expressing cancers.

12 Oct 2011

Aduro initiates CRS-207 and GVAX Pancreas Cancer Vaccine Phase 2 clinical trial

Aduro BioTech, Inc. announces the treatment of the first patient in the Phase 2 pancreatic cancer clinical trial of the sequential administration of two cancer vaccines: Aduro's CRS-207 and GVAX Pancreas Cancer Vaccine.

11 Oct 2011

FDA warns regarding danger of Listeria germs

If you eat food contaminated with bacteria called Listeria, you could get so sick that you have to be hospitalized. And for certain vulnerable people, the illness could be fatal.

1 Oct 2011

Contaminated Cantaloupes carrying listeria leads to one of the worst outbreaks

According to federal health officials Tuesday, at least 13 people are dead amid 72 sickened in 18 states in an outbreak of listeria food poisoning tied to contaminated cantaloupes.

28 Sep 2011

Listeria contamination in cantaloupes shipped to 10 states

Listeria-contaminated cantaloupes were shipped to five more states than was previously known, bringing to 22 the total number of states affected by an outbreak that killed eight people, the FDA announced last week.

26 Sep 2011

A code beyond DNA: Modified tRNA bases are characteristic of species

Our genetic code consists of four “letters” in the form of the nucleobases in our DNA and RNA. Three letters together form a “word” that are translated into an amino acid by tRNA and combined into proteins. Special markings subdivide the gene into active and inactive regions. A third possible level of information has so far received less attention: the chemical modification of tRNA nucleobases. In the journal Angewandte Chemie Thomas Carell and a team at the University of Munich have now demonstrated that tRNA modification profiles can be used for the characterization of species and the differentiation of pathogenic and nonpathogenic bacterial strains.

20 Sep 2011

Listeriosis outbreak sparks unofficial cantaloupe recall

At present the Food and Drug Administration (FDA) is working with the Centers for Disease Control and Prevention (CDC) to determine the source of contaminated cantaloupe blamed for the nationwide Listeriosis outbreak. Several Colorado grocery stores have removed cantaloupe from shelves, though there has been no official recall.

15 Sep 2011

CD8 alpha+ dendritic cells can help the body beat back infection

The same trait that makes a rare immune cell invaluable in fighting some infections also can be exploited by other diseases to cause harm, two new studies show.

29 Aug 2011

Insight into how bacterial toxins cause human diseases may help improve treatment

A better understanding of how bacterial toxins cause common human diseases may lead to their improved treatment and prevention according to a paper just published by Irish and US scientists in Nature Reviews Microbiology.

25 Aug 2011

Fresh food for years with newly discovered natural preservative

Scientists have discovered a natural preservative capable of destroying a whole class of bacteria, including E.coli and listeria and now food can be made to remain fresh and last for years. There would also be no need to refrigerate produce treated with the preservative, called, bisin, which is produced by harmless bacteria.

15 Aug 2011

Advaxis completes ADXS-PSA prostate cancer construct pre-IND meeting with the FDA

Advaxis, Inc.,, a leader in developing the next generation of immunotherapies for cancer and infectious diseases, has completed a pre-IND (Investigational New Drug) meeting with the FDA on August 10 to discuss the development plan for ADXS-PSA, a construct for the treatment of prostate cancer.

12 Aug 2011

Lantibiotic could prevent harmful bacteria in foods

University of Minnesota researchers have discovered and received a patent for a naturally occurring lantibiotic - a peptide produced by a harmless bacteria - that could be added to food to kill harmful bacteria like salmonella, E. coli and listeria.

5 Aug 2011

Researchers dissociate beneficial and detrimental impacts of maternal regulatory T cells

A normal but concerning consequence of pregnancy is the fact that pregnant women are more susceptible to infection. University of Minnesota Medical School researchers have identified the underlying mechanisms for this physiologic immune suppression that may lead to new therapies to help ward off infections during pregnancy.

22 Jul 2011

FDA warns consumers not to drink raw milk from Tucker Adkins Dairy

The FDA is working with officials in North Carolina and South Carolina to investigate an outbreak of campylobacteriosis in three people who consumed raw milk from Tucker Adkins Dairy in York, S.C. The three confirmed cases and another five probable cases are from three different households and each case reports that prior to becoming ill they consumed raw milk that was obtained from Tucker Adkins Dairy on June 14, 2011.

18 Jul 2011

First dog enters ADXS-HER2 dose-ranging study in canine osteosarcoma

Advaxis, Inc., a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announces that the first dog has entered a dose-ranging in canine osteosarcoma at the University of Pennsylvania School of Veterinary Medicine.

8 Jul 2011

FDA grants Advaxis pre-IND meeting for Advaxis-PSA immunotherapy for prostate cancer

Advaxis, Inc.,, a leader in developing the next generation of immunotherapies for cancer and infectious diseases, has been granted a pre-Investigational New Drug meeting with the U.S. Food and Drug Administration on August 10, 2011 to discuss the CMC, pharmacology, toxicology, and clinical plans for Advaxis PSA, its construct to fight prostate cancer.

1 Jul 2011