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Positive preliminary results from Alnylam's Phase I ALN-PCS trial on severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today the achievement of positive preliminary results from its ongoing clinical trial of ALN-PCS, an RNAi therapeutic targeting PCSK9 for the treatment of severe hypercholesterolemia.

5 Jan 2012

Study reveals possibility to selectively target and block crucial microRNA in liver cancer

A new study shows that it is possible to selectively target and block a particular microRNA that is important in liver cancer. The findings might offer a new therapy for this malignancy, which kills an estimated 549,000 people worldwide annually.

4 Jan 2012

Children with biliary atresia better tolerate maternal liver grafts

Children with a rare, life-threatening disease that is the most common cause of neonatal liver failure - biliary atresia - better tolerate liver transplants from their mothers than from their fathers, according to a UCSF-led study.

4 Jan 2012

BSD expands sales programs for MicroThermX Microwave Ablation System

BSD Medical Corporation, a leading provider of medical systems that utilize heat therapy to treat cancer, announced today that the Company is approaching 100 patients successfully treated with the MicroThermX Microwave Ablation System at hospitals throughout the U.S.

4 Jan 2012

Two new studies offer clearer picture of rise of hepatocellular carcinoma

Doctors have known for years that the incidence of deadly liver cancer is on the rise, but what is causing that trend has remained a mystery. Two recent Mayo Clinic studies published in the January issue of Mayo Clinic Proceedings offer a clearer picture of the rise of hepatocellular carcinoma (HCC), or liver cancer, which has tripled in the U.S. in the last three decades and has a 10 to 12 percent five-year survival rate when detected in later stages.

4 Jan 2012

Positive results from Can-Fite BioPharma's CF102 Phase 1/2 study on HCC

Can-Fite BioPharma Ltd, a biotechnology company developing small molecule drugs for the treatment of inflammatory, and liver diseases, traded on the Tel Aviv Stock Exchange announced today the successful results of the Phase 1/2 study of its drug candidate CF102 in the treatment of hepatocellular carcinoma.

4 Jan 2012

Scientists show how HCV virus hijacks miR-122 in liver cells

Viral diseases are still one of the biggest challenges to medical science. Thanks to thousands of years of co-evolution with humans, their ability to harness the biology of their human hosts to survive and thrive makes them very difficult to target with medical treatment.

2 Jan 2012

Detoxing this January useless but a long term effort may help: British Liver Trust

While many believe in detoxifying their systems after the season of indulgence, the British Liver Trust warns regarding January detoxes and urges people to think about their long-term health instead.

2 Jan 2012

Four or more coffees reduce risk of womb cancer

According to a new study drinking four or more cups of coffee a day may reduce risk of developing endometrial cancer or womb cancer by almost 25 per cent.

1 Jan 2012

Tips on how to avoid the misery of New Year's hangover

Loyola University Health System family physician Dr. Aaron Michelfelder offers tips on how to avoid the misery of a New Year's hangover.

30 Dec 2011

Increase in human activity threatens natural aquatic ecosystems in Tanzania

An increase in human activity is posing a threat to natural aquatic ecosystems in Tanzania and contributing to environmental damage and ecological changes. Doctoral research carried out by Hezron Emmanuel Nonga shows that agriculture and livestock farming leads to eutrophication in lakes and the proliferation of cyanobacteria which produce microcystins.

29 Dec 2011

Powerful painkiller on its way to the market: Experts worry about addiction woes

Drug makers are on their way to a pure, more powerful version of the nation’s second most-abused medicine, which has addiction experts worried that it could spur a new wave of abuse. The new pills contain the highly addictive painkiller hydrocodone, packing up to 10 times the amount of the drug as existing medications such as Vicodin.

28 Dec 2011

Donate Life to honor 10 deceased Hispanic organ and tissue donors with floragraphs

Almost 2,000 Hispanics donate organs every year in the United States, saving countless lives in the process, a contribution that will be recognized by the Donate Life float taking part in the 123rd Rose Parade in Pasadena. Five Hispanic men have been chosen to ride on the float as recognition for their gift of life to others through living donation or for the role they played in a deceased loved one's donation.

26 Dec 2011

Biosensors capable of detecting lung cancer in exhaled breath

Tecnalia, through the Interreg project Medisen, is contributing to develop biosensors capable of detecting the presence of tumour markers of lung cancer in exhaled breath.

23 Dec 2011

Scientists discover mechanism by which TNFα stimulates tumor formation

An inflammation-promoting protein triggers deactivation of a tumor-suppressor that usually blocks cancer formation via the NOTCH signaling pathway, a team of researchers led by scientists at The University of Texas MD Anderson Cancer Center reports today in Molecular Cell.

23 Dec 2011

Malaria vaccine shows early success

An experimental vaccine for malaria has been developed by British scientists. It has shown early potential to neutralize many, perhaps all, strains of the deadliest malaria parasite.

21 Dec 2011

CWRU receives NIDDK grant to study role of innate immunity in IBD

Investigators at Case Western Reserve University School of Medicine received a $6.75 million Program Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to study the role of innate immunity in inflammatory bowel disease.

21 Dec 2011

MU Department of Surgery continues to secure research opportunities

The University of Maryland School of Medicine Department of Surgery is continuing to secure research opportunities to advance the science of medicine and improve patient outcomes, as evidenced by the grants awarded to the Department by the National Institutes of Health.

20 Dec 2011

F. nucleatum alters endothelial integrity and allows other bacteria to invade human body

A common oral bacteria, Fusobacterium nucleatum, acts like a key to open a door in human blood vessels and leads the way for it and other bacteria like Escherichia coli to invade the body through the blood and make people sick, according to dental researchers at Case Western Reserve University.

16 Dec 2011

Researchers identify gene responsible for EMT transformation

Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have identified the gene GATA 6 as responsible for epithelial cells -which group together and are static- losing adhesion and moving towards a new site.

16 Dec 2011