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Malaria vaccine shows early success

An experimental vaccine for malaria has been developed by British scientists. It has shown early potential to neutralize many, perhaps all, strains of the deadliest malaria parasite.

21 Dec 2011

CWRU receives NIDDK grant to study role of innate immunity in IBD

Investigators at Case Western Reserve University School of Medicine received a $6.75 million Program Project Grant from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) to study the role of innate immunity in inflammatory bowel disease.

21 Dec 2011

MU Department of Surgery continues to secure research opportunities

The University of Maryland School of Medicine Department of Surgery is continuing to secure research opportunities to advance the science of medicine and improve patient outcomes, as evidenced by the grants awarded to the Department by the National Institutes of Health.

20 Dec 2011

F. nucleatum alters endothelial integrity and allows other bacteria to invade human body

A common oral bacteria, Fusobacterium nucleatum, acts like a key to open a door in human blood vessels and leads the way for it and other bacteria like Escherichia coli to invade the body through the blood and make people sick, according to dental researchers at Case Western Reserve University.

16 Dec 2011

Researchers identify gene responsible for EMT transformation

Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have identified the gene GATA 6 as responsible for epithelial cells -which group together and are static- losing adhesion and moving towards a new site.

16 Dec 2011

Study unveils mechanisms behind neurological effects of penitrem A

The mould fungus Penicillium crustosum occurs relatively frequently in food and animal fodder stored in temperate conditions. This mould produces powerful neurotoxins, for example penitrem A, which causes symptoms that are difficult to distinguish from those of other neurological diseases.

16 Dec 2011

Cancer-causing potential of fetal exposure to carcinogens can vary substantially

The cancer-causing potential of fetal exposure to carcinogens can vary substantially, a recent study suggests, causing different types of problems much later in life depending on the stage of pregnancy when the fetus is exposed.

16 Dec 2011

Viewpoints: Wyden and Ryan on their Medicare plan; Frist on the need for international health aid

Few issues draw more heated partisan rhetoric than the future of Medicare. Seniors are a reliable and powerful voting bloc, and both Republicans and Democrats are guilty of exploiting Medicare to frighten and entice voters. But turning discussions of Medicare's future into the third rail of American politics does nothing to guarantee that Medicare will continue to be a lifeline for America's seniors.

16 Dec 2011

Serotonin, wnt are in charge of asymmetrical right-left development in embryos

Spleen to the left, appendix to the right: In order for the body to sort itself out properly, two substances have to trigger a complex chain reaction, according to the latest findings at the University of Hohenheim.

16 Dec 2011

Mayo Clinic to build new cancer treatment facility

Mayo Clinic broke ground today for a cutting edge cancer therapy facility at its Phoenix campus. Construction begins this month on a $182 million facility to house Mayo Clinic's Proton Beam Therapy program - marking the beginning of a new era in cancer treatment.

15 Dec 2011

Stereotactic ablative radiotherapy may eradicate cancer

An innovative treatment technology could give cancer patients new hope for survival. In an international study based at Lawson Health Research Institute and London Health Sciences Centre's London Regional Cancer Program (LRCP), scientists are testing a therapy with the potential to eradicate cancers previously thought to be incurable.

15 Dec 2011

First Total Artificial Heart implant performed at NewYork-Presbyterian/Columbia

Surgeons at NewYork-Presbyterian Hospital/Columbia University Medical Center performed the first Total Artificial Heart implant in the New York City area to replace a patient's dying heart.

15 Dec 2011

Isis announces addition of three new drug development candidates

Isis Pharmaceuticals, Inc. announced today that it has added three new drugs to its development pipeline, ISIS-APOARx, ISIS-DGAT2Rx and ISIS-FVIIRx.

15 Dec 2011

Liver transplantations for NASH-Cirrhosis increase dramatically

Nonalcoholic steatohepatitis (NASH) occurs when fat builds up in the liver. This accumulation of fat damages the liver and leads to cirrhosis. NASH is rapidly increasing in the U.S. mainly related to the epidemics of obesity and diabetes.

15 Dec 2011

Maraviroc reduces incidence of GvHD in blood cancer patients after ASCT

An HIV drug that redirects immune cell traffic appears to significantly reduce the dangerous complication graft-versus-host disease (GvHD) in blood cancer patients following allogeneic stem cell transplantation (ASCT), according to new research from the Perelman School of Medicine at the University of Pennsylvania that will be presented today at the 53rd American Society of Hematology Annual Meeting.

14 Dec 2011

Macrophages play a role in brown fat metabolism

Throughout the interior spaces of humans and other warm-blooded creatures is a special type of tissue known as brown fat, which may hold the secret to diets and weight-loss programs of the future.

14 Dec 2011

Microwave ablation therapy may be safe, effective for pulmonary metastases

Covidien, a leading global provider of healthcare products, today announced that Radiology, the monthly journal of the Radiological Society of North America, has published a new research study led by Prof. Thomas J. Vogl, MD, entitled, "Microwave Ablation Therapy: Clinical Utility in Treatment of Pulmonary Metastases."

14 Dec 2011

Scientists identify A2bAR as possible new therapeutic target against atherosclerosis

Researchers from Boston University School of Medicine (BUSM) have identified for the first time the A2b adenosine receptor (A2bAR) as a possible new therapeutic target against atherosclerosis resulting from a diet high in fat and cholesterol.

13 Dec 2011

New high-alcohol-seeking mice mimics human consumption patterns

A line of laboratory mice developed by a researcher from the School of Science at Indiana University-Purdue University Indianapolis drinks more alcohol than other animal models and consumes it in a fashion similar to humans: choosing alcohol over other options and binge drinking.

13 Dec 2011

ISIS-FXIRx reduces Factor XI activity without bleeding in healthy volunteers

Isis Pharmaceuticals, Inc. announced today positive results from a Phase 1 study with ISIS-FXIRx. The results demonstrated that treatment with ISIS-FXIRx produced dose-dependent statistically significant reductions of up to 78 percent in Factor XI activity.

13 Dec 2011