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Octapharma completes clinical development of Uniplas human pooled plasma

Octapharma AG, one of the largest private manufacturers of plasma products in the world, announced today that the clinical development for Uniplas® has been successfully completed. The product has been filed for registration in Europe and will be submitted later in the USA.

26 Aug 2010

PLX4032 therapy results in tumor shrinkage in metastatic melanoma patients

A multicenter study has concluded that treatment with a new targeted therapy called PLX4032 (also called RG7204) resulted in significant tumor shrinkage in 80 percent of patients with advanced melanoma.

26 Aug 2010

Developing specific liver cell lines from stem cells holds promise for new liver disease treatment: Researchers

By creating diseased liver cells from a small sample of human skin, scientists have for the first time shown that stem cells can be used to model a diverse range of inherited disorders. The University of Cambridge researchers' findings, which will hopefully lead to new treatments for those suffering from liver diseases, were published today in The Journal of Clinical Investigation.

26 Aug 2010

FDA grants LFB's recombinant anti-CD20 monoclonal antibody orphan drug status for CLL

The recombinant anti-CD20 monoclonal antibody produced by LFB Biotechnologies received orphan drug status for the treatment of Chronic Lymphocytic Leukemia (CLL). This approval from the FDA Office of Orphan Products Development was granted on August 6th, 2010.

26 Aug 2010

Naringenin from grape fruits initiates increased fatty acid oxidation, inhibits vLDL production

Naringenin, an antioxidant derived from the bitter flavor of grapefruits and other citrus fruits, may cause the liver to break down fat while increasing insulin sensitivity, a process that naturally occurs during long periods of fasting.

26 Aug 2010

Researchers prove iPS cells can help to treat liver diseases

Great excitement greeted the discovery a few years ago that certain cells from mice and humans could be reprogrammed to become inducible pluripotent stem cells (iPS cells), as they hold promise for cell replacement therapy and modeling human disease.

26 Aug 2010

MRI and MR spectroscopy determine internal fat distribution: Study

Why is it that some people lose weight and body fat when they exercise and eat less and others don't. German researchers say MRI and magnetic resonance (MR) spectroscopy can provide the answer and help predict who will benefit from lifestyle changes.

25 Aug 2010

FDA grants Fast Track Designation to Celsion's ThermoDox for liver cancer treamtment

Celsion Corporation, a leading oncology drug development company, today announced that the U.S. Food and Drug Administration has designated the HEAT Study of its investigational drug, ThermoDox, in combination with radiofrequency ablation, as a Fast Track Development Program.

25 Aug 2010

Scientists develop nano-sized vehicle to deliver chemotherapy drugs directly into cancer cells

Chemotherapy, while an effective cancer treatment, also brings debilitating side effects such as nausea, liver toxicity and a battered immune system.Now, a new way to deliver this life-saving therapy to cancer patients getting straight to the source of the disease.

24 Aug 2010

SEB opens new state-of-the-art laboratory operation, R&D facility

Cryo-Cell International, Inc., one of the largest and most established leaders in stem cell innovation today announced that S-Evans Biosciences, the Company's exclusive Célle menstrual stem cell technology license partner in China has opened a new state-of-the-art laboratory operation and research & development facility located in a Hi-Tech park designated to become an epicenter for stem cell and genomics R&D; cellular therapies and stem cell cryopreservation services.

23 Aug 2010

Hepatitis E vaccine successful in clinical trial: Study

In a Clinical trial in China, a vaccine has been found to protect against Hepatitis E. Hepatitis E virus, usually spread via contaminated food and faeces usually runs its course before the patient recovers. However it can cause severe illness in elderly people and has a mortality rate of 1 to 3 percent. It can also kill 5 to 25 percent of affected pregnant women and those who survive can suffer high rates of miscarriage. Around a third of the world's population have been infected by the virus say researchers.

22 Aug 2010

FDA extends review on Acetadote for non-acetaminophen acute liver failure

Cumberland Pharmaceuticals Inc. today announced the U.S. Food and Drug Administration (FDA) has extended its review of the supplemental new drug application (sNDA) for the use of Acetadote® (acetylcysteine) Injection in patients with non-acetaminophen acute liver failure.

21 Aug 2010

Cyprotex launches new in vitro toxicology service

Cyprotex PLC, the preclinical ADME Tox services company, today announces the launch of its new in vitro toxicology service, branded as Cyprotox(R). Supporting the new service is an additional 90 square metres of laboratory space at Cyprotex's Macclesfield, UK facility housing the latest technology in multi-parametric automated fluorescent imaging and cellular analysis. This gives Cyprotex's Macclesfield site the same in vitro toxicology capabilities as those of Apredica (Watertown, MA, USA), which Cyprotex acquired on 6 August 2010.

From Thermo Fisher Scientific Inc. 20 Aug 2010

Study links obesity rates with walking and cycling rates

A study authored by Professor David Bassett Jr. from the Department of Kinesiology, Recreation and Sport Studies at the University of Tennessee, Knoxville, and three other researchers was published in the American Journal of Public Health, concluding that communities with more walkers and cyclists are healthier than those where people must rely on cars to get around.

20 Aug 2010

Study finds Hispanics, Asians less likely to receive liver transplants

Researchers at the University of Michigan and Arbor Research Collaborative for Health, both in Ann Arbor, have identified geographic variation as a key factor accounting for disparities in access to liver transplantation among racial and ethnic groups.

20 Aug 2010

Trial shows positive results for radioembolisation technique for colorectal cancer liver metastases treatment

Using the innovative technique of radioembolisation to treat patients with inoperable colorectal cancer liver metastases who have failed all standard-of-care chemotherapy options can more than double the time until their disease progresses, according to the final results of a Phase III randomised controlled trial published in the prestigious Journal of Clinical Oncology.

20 Aug 2010

SIR-Spheres safe, effective for patients with colorectal cancer liver metastases who have failed chemotherapy

Radioactive yttrium-90 labelled resin microspheres (SIR-Spheres; Sirtex Medical, Sydney, Australia) appear to be a safe and effective treatment for patients with colorectal cancer liver metastases who have failed available chemotherapy options, according to the final results of a prospective clinical multi-centre phase II trial conducted by the Italian Society of Locoregional Therapies in Oncology (SITILO) and published in the British Journal of Cancer.

20 Aug 2010

FDA Advisory Committee votes in favor of expanding pain indications for Eli Lilly's Cymbalta

The U.S. Food and Drug Administration (FDA) Anesthetic and Life Support Drugs Advisory Committee voted 8-6 in favor of expanding the pain indications for Eli Lilly and Company's (NYSE: LLY) Cymbalta® (duloxetine HCl) to a broader pain population that will be further defined by the FDA, if approved.

20 Aug 2010

Effects of illegal drugs on health

Illegal drugs are responsible for up to 1,600 deaths a year in the UK, and destroy thousands of relationships, families and careers. Find out about the most commonly used illegal drugs in England and Wales and the effects they can have on your health.

19 Aug 2010

Second round of abstract submission for International Symposium on MR-guided Focused Ultrasound

Due to overwhelming response from researchers, a second round of abstract submissions for the upcoming 2nd International Symposium on MR-guided Focused Ultrasound will open on Monday, August 23, 2010, nine days earlier than previously announced. The submission deadline will be moved forward to Monday, September 6, 2010.

19 Aug 2010

Liver News and Research

Octapharma completes clinical development of Uniplas human pooled plasma

PLX4032 therapy results in tumor shrinkage in metastatic melanoma patients

Developing specific liver cell lines from stem cells holds promise for new liver disease treatment: Researchers

FDA grants LFB's recombinant anti-CD20 monoclonal antibody orphan drug status for CLL

Naringenin from grape fruits initiates increased fatty acid oxidation, inhibits vLDL production

Researchers prove iPS cells can help to treat liver diseases

MRI and MR spectroscopy determine internal fat distribution: Study

FDA grants Fast Track Designation to Celsion's ThermoDox for liver cancer treamtment

Scientists develop nano-sized vehicle to deliver chemotherapy drugs directly into cancer cells

SEB opens new state-of-the-art laboratory operation, R&D facility

Hepatitis E vaccine successful in clinical trial: Study

FDA extends review on Acetadote for non-acetaminophen acute liver failure

Cyprotex launches new in vitro toxicology service

Study links obesity rates with walking and cycling rates

Study finds Hispanics, Asians less likely to receive liver transplants

Trial shows positive results for radioembolisation technique for colorectal cancer liver metastases treatment

SIR-Spheres safe, effective for patients with colorectal cancer liver metastases who have failed chemotherapy

FDA Advisory Committee votes in favor of expanding pain indications for Eli Lilly's Cymbalta

Effects of illegal drugs on health

Second round of abstract submission for International Symposium on MR-guided Focused Ultrasound

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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