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Food insecurity fuels fatty liver disease in Latinx kids

For Latinx kids, unreliable access to food at age 4 raises the odds of having fatty liver disease later in childhood by nearly four times, a new UC San Francisco-led study found.

9 Mar 2024

New PET radiotracer distinguishes diseased tissues based on fructose metabolism

A new PET radiotracer can differentiate diseased tissues from healthy tissues based on fructose metabolism, according to new research published in the March issue of The Journal of Nuclear Medicine.

8 Mar 2024

Breakthrough in CRISPR delivery promises safer gene editing

Recent research in PNAS highlights advancements in non-viral, cell-specific delivery methods for CRISPR-Cas systems, emphasizing their potential to enhance research and gene therapy applications by minimizing risks associated with off-target effects and improving targeted delivery.

7 Mar 2024

Common age-associated changes in the blood found to be a risk factor for acute kidney injury

A U.S.-Canadian research collaboration led by Vanderbilt University Medical Center has identified common, age-associated changes in the blood as a risk factor for acute kidney injury (AKI), which occurs in more than 1 in 5 hospitalized adults worldwide.

7 Mar 2024

Genetic study reveals insights into ancestry-associated differences in type 2 diabetes

The development and progression of type 2 diabetes are affected by numerous biological processes, such as the body's response to insulin, the health of insulin-producing pancreatic beta cells, and the functioning of metabolic pathways.

6 Mar 2024

NIH study reveals elevated cholesterol levels among American Indian youth

More than 70% of American Indian young adults aged 20-39 and 50% of American Indian teens have cholesterol levels or elevated fat in the blood that put them at risk for cardiovascular disease, suggests a study supported by the National Institutes of Health.

6 Mar 2024

Human molecular adaptations to fasting: Insights from proteomic analysis

Researchers investigate systemic proteome adaptations to one week of fasting in humans.

6 Mar 2024

Study shows semaglutide as a safe and effective therapy for MASLD in people with HIV

A weekly injection of semaglutide was safe and reduced the amount of fat in the liver by 31% in people with HIV and metabolic dysfunction-associated steatotic liver disease (MASLD), according to a presentation today at the 2024 Conference on Retroviruses and Opportunistic Infections (CROI) in Denver.

5 Mar 2024

Growing mini-organs from amniotic fluid to treat conditions before birth

A pioneering approach, developed by researchers at UCL and Great Ormond Street Hospital (GOSH), means human development can be observed in late pregnancy for the first time, raising the possibility of monitoring and treating congenital conditions before birth.

5 Mar 2024

Robotic-assisted surgery for gallbladder cancer found to be as effective as traditional methods

Each year, approximately 2,000 people die annually of gallbladder cancer (GBC) in the U.S., with only one in five cases diagnosed at an early stage. With GBC rated as the first biliary tract cancer and the 17th most deadly cancer worldwide, pressing attention for proper management of disease must be addressed.

5 Mar 2024

Nomogram could be a game-changer for predicting alcohol-related liver cancer risk

Liver cancer, unfortunately, is the sixth most common cancer and the third most frequent cause of cancer-related death globally.

5 Mar 2024

Researchers take important step toward genetic therapy for hereditary conditions

Researchers who work with tiny drug carriers known as lipid nanoparticles have developed a new type of material capable of reaching the lungs and the eyes, an important step toward genetic therapy for hereditary conditions like cystic fibrosis and inherited vision loss.

5 Mar 2024

Sleep apnea in heart failure: Women face higher hospitalization risks

Study reveals sex-associated differences in cardiovascular outcomes for heart failure patients with sleep apnea, highlighting higher risks for women with obstructive sleep apnea.

4 Mar 2024

AI-powered transfer learning approach predicts gene perturbations that transform cell behavior

Technological advances in gene sequencing and computing have led to an explosion in the availability of bioinformatic data and processing power, respectively, creating a ripe nexus for artificial intelligence (AI) to design strategies for controlling cell behavior.

4 Mar 2024

UCSF scientists discover less invasive prenatal treatment for Angelman syndrome

In a discovery that opens the door to a less invasive way of treating some serious disorders before birth, UC San Francisco scientists have found that delivering medicine through amniotic fluid is as effective as delivering it to the fetal brain via cerebrospinal fluid.

4 Mar 2024

Penn engineers develop targeted lung delivery system using lipid nanoparticles

Penn Engineers have developed a new means of targeting the lungs with lipid nanoparticles (LNPs), the miniscule capsules used by the Moderna and Pfizer-BioNTech COVID-19 vaccines to deliver mRNA, opening the door to novel treatments for pulmonary diseases like cystic fibrosis.

1 Mar 2024

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Researchers developed an engineered transcriptional repressor that durably silences the Pcsk9 gene in mice, reducing cholesterol levels for up to a year with a single treatment, showcasing a potential breakthrough in genetic disorder treatments without the risks of DNA mutation.

29 Feb 2024

SickKids study offers new path for pediatric rare disease clinical trials

Using a novel methodology, researchers at The Hospital for Sick Children (SickKids) are the first in pediatric research to use data from an international real-world cohort to overcome the barriers associated with conducting randomized clinical trials in children with rare diseases.

29 Feb 2024

Study: Potential biomarker in the blood predicts sudden cardiac deaths

The discovery of a biomarker readily measured in blood could be a significant step towards preventing sudden deaths.

28 Feb 2024

Using machine learning to identify key predictors of mortality in dementia patients

Researchers at the Icahn School of Medicine at Mount Sinai and others have harnessed the power of machine learning to identify key predictors of mortality in dementia patients.

28 Feb 2024

Liver News and Research

Food insecurity fuels fatty liver disease in Latinx kids

New PET radiotracer distinguishes diseased tissues based on fructose metabolism

Breakthrough in CRISPR delivery promises safer gene editing

Common age-associated changes in the blood found to be a risk factor for acute kidney injury

Genetic study reveals insights into ancestry-associated differences in type 2 diabetes

NIH study reveals elevated cholesterol levels among American Indian youth

Human molecular adaptations to fasting: Insights from proteomic analysis

Study shows semaglutide as a safe and effective therapy for MASLD in people with HIV

Growing mini-organs from amniotic fluid to treat conditions before birth

Robotic-assisted surgery for gallbladder cancer found to be as effective as traditional methods

Nomogram could be a game-changer for predicting alcohol-related liver cancer risk

Researchers take important step toward genetic therapy for hereditary conditions

Sleep apnea in heart failure: Women face higher hospitalization risks

AI-powered transfer learning approach predicts gene perturbations that transform cell behavior

UCSF scientists discover less invasive prenatal treatment for Angelman syndrome

Penn engineers develop targeted lung delivery system using lipid nanoparticles

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

SickKids study offers new path for pediatric rare disease clinical trials

Study: Potential biomarker in the blood predicts sudden cardiac deaths

Using machine learning to identify key predictors of mortality in dementia patients

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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