Liver Disease News and Research

RSS

The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

Non-alcoholic fatty liver disease (NAFLD) has emerged as a leading cause of chronic liver disease worldwide, affecting approximately 38% of the global population from 2016 to 2019.

25 Jul 2024

New study helps better understand the pathology of fatty liver disease MASH

A new study brings researchers closer to better understanding the pathology of the fatty liver disease MASH, which stands for metabolic dysfunction-associated steatohepatitis.

24 Jul 2024

Beyond the anti-obesity benefits of glucagon-like peptide-1 drugs

The advantages of glucagon-like peptide-1 (GLP-1) medicines beyond glycemic and weight control.

23 Jul 2024

Exploring the expanding horizons of GLP-1 therapies beyond diabetes and obesity

In a Perspective, Daniel Drucker highlights the growing body of evidence that hints at the potential of glucagon-like peptide-1 (GLP-1)-based medications in treating conditions other than diabetes and obesity, including cardiovascular disease and neurodegenerative disorders.

18 Jul 2024

Spinal Muscular Atrophy patients are at higher risk of developing fatty liver disease

An international study has discovered that people living with the neurodegenerative condition Spinal Muscular Atrophy (SMA) are at higher risk of developing fatty liver disease, suggesting that SMA patients may face additional health problems over time.

17 Jul 2024

CePA: Novel nanomedicine for alleviating MASH via mTOR repression

Metabolic dysfunction-associated steatohepatitis (MASH) is one of the most common chronic liver diseases, primarily caused by metabolic disorders and systemic inflammatory responses.

16 Jul 2024

Ultrasound techniques for the surveillance, diagnosis, and treatment of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a primary malignancy of the liver and one of the leading causes of cancer-related deaths worldwide. Early detection and accurate diagnosis are crucial for effective management and improved survival rates.

16 Jul 2024

What is the association of Mediterranean diet–based interventions with cardiometabolic biomarkers in children and adolescents?

Researchers reviewed and meta-analyzed the randomized clinical trials (RCTs) assessing the effects of Mediterranean diet -based interventions on cardiometabolic biomarkers in children and adolescents.

16 Jul 2024

UChicago expands microbiome research capabilities with new manufacturing facility

The Duchossois Family Institute (DFI) at the University of Chicago can manufacture clinical-grade encapsulated bacteria – catalyzing opportunities to better understand the microbiome and its myriad of roles in human health.

16 Jul 2024

SH2B1 gene defends against obesity via the paraventricular hypothalamus

Obesity is a complicated condition, caused by a combination of genetics, the food environment, behavior, and other factors.

15 Jul 2024

Do probiotics really benefit healthy people?

Recent research in Advances In Nutrition reviews the benefits of probiotics for healthy individuals, highlighting evidence gaps and the need for further study to support preventive recommendations.

14 Jul 2024

The effect of supplementation with cornelian cherry on different cardiometabolic outcomes

A recent meta-analysis in Nutrients examined recent studies on the cornelian cherry, Cornus mas L., for evidence of its cardiometabolic benefit.

11 Jul 2024

Existing drug shows promise for treating common liver disease

The University of Barcelona has led a study that suggests using the drug known as pemafibrate to treat liver disease associated with metabolic disorders, the most common liver pathology in the world, which affects one in four people. The drug has long been marketed in Japan for another use: improving blood lipid levels in patients with hyperlipidaemia, a common condition in diabetics. Now, however, it could help address this serious liver disease, which still has no specific treatment.

11 Jul 2024

Aging aggravates liver fibrosis in Down Syndrome, new study finds

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 12, entitled, "Aging exacerbates oxidative stress and liver fibrosis in an animal model of Down Syndrome."

10 Jul 2024

Repurposing pemafibrate to treat liver disease associated with metabolic disorders

10 Jul 2024

Insilico Medicine and Fosun Pharma deliver second preclinical candidate for solid tumor treatment

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven drug discovery company, has successfully delivered the second preclinical candidate compound (PCC) in its collaboration with Fosun Pharma in June 2024, a potential innovative therapeutic using synthetic lethal strategy for the treatment of solid tumors.

5 Jul 2024

Decoding the significance of subnormal liver enzyme activity

Liver diseases are commonly diagnosed using serum enzyme assays, particularly for aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma-glutamyl transpeptidase (GGT), and 5'-nucleotidase (5'-NT).

3 Jul 2024

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

Hepatocellular carcinoma (HCC), a leading cause of cancer-related mortality globally, exhibits a dismal five-year survival rate of only 18%.

2 Jul 2024

No organ is an island: Genetic study shows unique but interconnected aging markers

Researchers analyzed genetic underpinnings of biological age gaps in nine organ systems using a large dataset from the U.K. Biobank, revealing organ-specific yet interconnected genetic architectures. Their findings may aid in understanding complex diseases and developing holistic treatments.

2 Jul 2024

KRISS develops world's first reference material for accurate body fat measurement in medical imaging

The Korea Research Institute of Standards and Science (KRISS) has developed the world's first reference material to improve the accuracy of body fat measurements conducted through MRI and CT scans.

1 Jul 2024

Liver Disease News and Research

Further Reading

Understanding the epigenetic regulation of hepatic stellate cells in NAFLD

New study helps better understand the pathology of fatty liver disease MASH

Beyond the anti-obesity benefits of glucagon-like peptide-1 drugs

Exploring the expanding horizons of GLP-1 therapies beyond diabetes and obesity

Spinal Muscular Atrophy patients are at higher risk of developing fatty liver disease

CePA: Novel nanomedicine for alleviating MASH via mTOR repression

Ultrasound techniques for the surveillance, diagnosis, and treatment of hepatocellular carcinoma

What is the association of Mediterranean diet–based interventions with cardiometabolic biomarkers in children and adolescents?

UChicago expands microbiome research capabilities with new manufacturing facility

SH2B1 gene defends against obesity via the paraventricular hypothalamus

Do probiotics really benefit healthy people?

The effect of supplementation with cornelian cherry on different cardiometabolic outcomes

Existing drug shows promise for treating common liver disease

Aging aggravates liver fibrosis in Down Syndrome, new study finds

Repurposing pemafibrate to treat liver disease associated with metabolic disorders

Insilico Medicine and Fosun Pharma deliver second preclinical candidate for solid tumor treatment

Decoding the significance of subnormal liver enzyme activity

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

No organ is an island: Genetic study shows unique but interconnected aging markers

KRISS develops world's first reference material for accurate body fat measurement in medical imaging

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

Latest News