Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Hepatitis C virus rarely transmitted through sex between monogamous heterosexuals

Individuals infected by the hepatitis C virus (HCV) have nothing to fear from sex in a monogamous, heterosexual relationship. Transmission of HCV from an infected partner during sex is rare according to new research published in the March issue of Hepatology, a journal published by Wiley on behalf of the American Association for the Study of Liver Diseases (AASLD).

19 Mar 2013

Researchers find white blood cells produce and eliminate RBCs

Researchers at Albert Einstein College of Medicine of Yeshiva University and the Icahn School of Medicine at Mount Sinai have found that macrophages - white blood cells that play a key role in the immune response - also help to both produce and eliminate the body's red blood cells (RBCs).

18 Mar 2013

EASL urges UK to press ahead with proposed implementation of minimum unit pricing of alcohol

According to WHO, liver cirrhosis accounts for 1.8% (i.e. 170,000) of all deaths in Europe. In recent years liver cirrhosis has become a serious health threat in some Western European countries such as Ireland and the United Kingdom, where over the last 10 years the associated mortality has increased.

15 Mar 2013

Einstein researchers to develop drug-impregnated intravaginal ring for HIV prevention in women

Researchers at Albert Einstein College of Medicine of Yeshiva University have been awarded a $12 million grant from the National Institutes of Health (NIH) to develop a drug-impregnated intravaginal ring to prevent HIV infection in women.

11 Mar 2013

Drugs that combat ageing may be available within five years

Drugs that combat ageing may be available within five years, following landmark work led by an Australian researcher.

11 Mar 2013

Laboratorios Grifols, Cadence announce new supply agreement for OFIRMEV

Cadence Pharmaceuticals, Inc., a biopharmaceutical company focused on acquiring, in-licensing, developing and commercializing proprietary products principally for use in the hospital setting, today announced a new supply agreement with Laboratorios Grifols, S.A. for the development, manufacture and supply of commercial quantities of OFIRMEV (acetaminophen) injection in flexible plastic bags.

6 Mar 2013

Deleting Plin2 gene prevents obesity in mice

Researchers have discovered that deleting a specific gene in mice prevents them from becoming obese even on a high fat diet, a finding they believe may be replicated in humans.

6 Mar 2013

HIV might promote aging and disease progression in people with HCV, study results suggest

Infectious disease experts at Johns Hopkins have found that among people infected with the hepatitis C virus, co-infection with HIV, speeds damage and scarring of liver tissue by almost a decade.

5 Mar 2013

Oxidative stress turns protein that protects healthy cells into executioner: Study

Oxidative stress turns a protein that normally protects healthy cells into their executioner, according to a study released today in the Proceedings of the National Academy of Sciences journal.

5 Mar 2013

HCV and HIV co-infected patients achieve early treatment success with faldaprevir, PegIFN/RBV

Interim study results from STARTversoTM 4 presented today at CROI+ show that 80 percent of hepatitis C (HCV) patients also infected with HIV achieved early treatment success with faldaprevir (BI 201335) combined with pegylated interferon and ribavirin (PegIFN/RBV).

5 Mar 2013

Urea cycle disorder patient successfully treated by Promethera(R) HepaStem in Phase I/II trial in France

Promethera Biosciences, a Belgian biotechnology company developing Promethera(R) HepaStem, a cell-based therapy for the treatment of liver-based metabolic diseases including Crigler-Najjar Syndrome and Urea Cycle Disorders, announced that it has successfully treated a patient with liver progenitor cells enrolled in its Phase I/II trial.

1 Mar 2013

Einstein researchers to investigate consequences of soccer heading on the brain

Sports-related concussion is an increasingly recognized public health problem. At least 1.6 million sports- and recreation-related traumatic brain injuries occur in the United States annually. While the primary focus has been on football, soccer has come under greater scrutiny.

28 Feb 2013

Wnt-induced Lgr5 expression marks stem cell production in the liver

For decades scientists around the world have attempted to regenerate primary liver cells known as hepatocytes because of their numerous biomedical applications, including hepatitis research, drug metabolism and toxicity studies, as well as transplantation for cirrhosis and other chronic liver conditions. But no lab in the world has been successful in identifying and growing liver stem cells in culture -- using any available technique - until now.

26 Feb 2013

N-acetylcysteine improves graft survival following liver transplantation

Researchers from Italy have found that the antioxidant, N-acetylcysteine (NAC), when injected prior to harvesting of the liver, significantly improves graft survival following transplantation.

26 Feb 2013

Antioxidant boosts liver transplant outcomes

Infusion of N-acetylcysteine in liver donors can significantly improve the outcome of transplantation, research shows.

25 Feb 2013

Janssen submits simeprevir regulatory application in Japan to treat HCV

Medivir AB today announced that its partner Janssen now has submitted a regulatory application to the Japanese Ministry of Health & Welfare authorities seeking approval for simeprevir, administered with pegylated interferon (Peg-IFN) and ribavirin (RBV) for the treatment of genotype 1 chronic hepatitis C patients who are treatment naïve, prior non responders or relapsed following treatment with Peg-IFN with or without RBV.

22 Feb 2013

EASL unveils new publication - The burden of liver disease in Europe

Major progress has been made in the past 30 years in the knowledge and management of liver disease, yet approximately 29 million Europeans still suffer from a chronic liver condition. The European Association for the Study of the Liver (EASL) today unveiled its new publication The burden of liver disease in Europe: a review of available epidemiological data.

22 Feb 2013

Donated liver survival rate improved by antioxidant

Researchers from Italy have found that the antioxidant, N-acetylcysteine (NAC), when injected prior to harvesting of the liver, significantly improves graft survival following transplantation. Results published in the February issue of Liver Transplantation, a journal of the American Association for the Study of Liver Diseases (AASLD), suggest that the NAC effect on early graft function and survival is higher when suboptimal organs are used.

21 Feb 2013

Physicians do not talk to patients about psychosocial impact and long-term risks of ICDs

New research at Saint Louis University shows physicians do not talk to patients about the psychosocial impact and long-term risks of implanting cardioverter defibrillators (ICDs) to treat irregular heart rhythms, leaving them misinformed about how the device may affect quality of life.

20 Feb 2013

Defensive medicine under attack

Around one-eighth of all requests for tests and procedures by gastroenterologists are attributable to the practice of defensive medicine, Italian research shows.

14 Feb 2013

Liver Disease News and Research

Further Reading

Hepatitis C virus rarely transmitted through sex between monogamous heterosexuals

Researchers find white blood cells produce and eliminate RBCs

EASL urges UK to press ahead with proposed implementation of minimum unit pricing of alcohol

Einstein researchers to develop drug-impregnated intravaginal ring for HIV prevention in women

Drugs that combat ageing may be available within five years

Laboratorios Grifols, Cadence announce new supply agreement for OFIRMEV

Deleting Plin2 gene prevents obesity in mice

HIV might promote aging and disease progression in people with HCV, study results suggest

Oxidative stress turns protein that protects healthy cells into executioner: Study

HCV and HIV co-infected patients achieve early treatment success with faldaprevir, PegIFN/RBV

Urea cycle disorder patient successfully treated by Promethera(R) HepaStem in Phase I/II trial in France

Einstein researchers to investigate consequences of soccer heading on the brain

Wnt-induced Lgr5 expression marks stem cell production in the liver

N-acetylcysteine improves graft survival following liver transplantation

Antioxidant boosts liver transplant outcomes

Janssen submits simeprevir regulatory application in Japan to treat HCV

EASL unveils new publication - The burden of liver disease in Europe

Donated liver survival rate improved by antioxidant

Physicians do not talk to patients about psychosocial impact and long-term risks of ICDs

Defensive medicine under attack

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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