Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Obese youths with particular genetic variants may be more prone to fatty liver disease

Obese youths with particular genetic variants may be more prone to fatty liver disease, a leading cause of chronic liver disease in children and adolescents in industrialized countries, according to new findings by Yale School of Medicine researchers.

27 Mar 2012

High-fat, low-carb foods linked with increased risk of heart attack in obese people

High-fat, low-carb foods are a popular choice for dieters, but new laboratory research by University of Alabama at Birmingham cardiologists indicates these may be detrimental to the health of people who have ischemic cardiovascular disease or a predisposition to heart attacks.

26 Mar 2012

Alcohol linked to 25% increase in liver disease deaths

The first report from the fledgling National End of Life Care Intelligence Network warns that the victims of liver disease are getting younger, with deaths increasing among people in their forties. Deaths rose from 9,231 in 2001 to 11,575 in 2009; some 60% of these were men, and 90% of them were under 70. Deaths are more common in England's northern regions marked by high unemployment and low educational achievement.

25 Mar 2012

Obese children with PNPLA3 and GCKR genetic variants more susceptible to fatty liver disease

New research found the genetic variant Patatin-like phospholipase domain containing protein-3 (PNPLA3) acting in conjunction with the glucokinase regulatory protein (GCKR) is associated with increased susceptibility to fatty liver disease in obese children.

23 Mar 2012

HCC patients have reduced risk of waitlist mortality

New research shows increasing disparity in mortality among candidates with and without hepatocellular carcinoma (HCC) who are on the waiting list for liver transplantation. The study available in the April issue of Liver Transplantation, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases, found that liver cancer patients are less likely to die on the wait list than non-HCC candidates, prompting transplantation specialists to suggest a reevaluation of current allotment criteria for those with HCC.

23 Mar 2012

Hyperion acquires worldwide rights to Ucyclyd's Ravicti

Hyperion Therapeutics, Inc. today announced that it has acquired worldwide rights to the investigational drug Ravicti from Ucyclyd Pharma, Inc., a wholly owned subsidiary of Medicis Pharmaceutical Corporation.

23 Mar 2012

Chemists produce first high resolution structure of HCV viral RNA-inhibitor complex

Chemists at the University of California, San Diego have produced the first high resolution structure of a molecule that when attached to the genetic material of the hepatitis C virus prevents it from reproducing.

20 Mar 2012

Einstein members celebrate 2012 Match Day

Members of Albert Einstein College of Medicine of Yeshiva University's graduating class celebrated another strong year for residency placements in competitive specialties and prestigious programs at this year's Match Day. Representing the culmination of their medical school education, Match Day marked the transition of Einstein's class of 2012 into the post-graduate phase of their training - when they will practice medicine in a clinical setting under the supervision of fully licensed physicians.

17 Mar 2012

EORTC, EASL publish first joint CPGs on management of hepatocellular carcinoma

The European Association for the Study of the Liver (EASL) and the European Organisation for Research and Treatment of Cancer (EORTC) today publish their first joint Clinical Practice Guidelines (CPGs) on the management of hepatocellular carcinoma.

16 Mar 2012

Health Canada approves Mylan-Rosuvastatin Calcium Tablets

Mylan Pharmaceuticals ULC, the Canadian subsidiary of Mylan Inc., today received approval from Health Canada for Mylan-Rosuvastatin Calcium Tablets, 5mg, 10mg, 20mg and 40mg. Mylan-Rosuvastatin is the generic version of Astra Zeneca's Crestor Tablets, which are used for the management of primary hypercholesterolaemia, mixed dyslipidaemia, and familial hypercholesterolaemia.

16 Mar 2012

Linking HCV infected people with care is key to reducing related mortality and morbidity

Broader screening to identify people infected with hepatitis C virus (HCV) would likely be cost effective, according to a new report published in Clinical Infectious Diseases.

15 Mar 2012

Einstein earns an 'A' for conflict-of-interest policies from AMSA

Albert Einstein College of Medicine of Yeshiva University has earned an "A," the top mark, for its conflict-of-interest policies from the American Medical Student Association (AMSA), the oldest and largest independent association of physicians-in-training in the United States.

13 Mar 2012

Medivir initiates two new HPC3001 and HPC3011 phase III trials in HCV

MedivirAB a research based specialty pharmaceutical company focused on infectious diseases announces that its oral, once daily investigational protease inhibitor TMC435, developed by Janssen Pharmaceuticals for the treatment of Hepatitis C virus (HCV), has commenced patient dosing and started screening in two new phase III clinical trials, HPC3001 and HPC3011, respectively.

13 Mar 2012

U-M to research into treatment for hepatitis C

The Greenview Foundation has announced a gift of $57,000 to the University of Michigan Health System to support research on a treatment for hepatitis C.

12 Mar 2012

Middle aged ignoring health messages on alcohol consumption

A new survey finds that adults aged 45 and over are more than three times as likely to drink alcohol almost every day as those under 45. This could mean that the middle aged population is ignoring the serious health risks associated with excessive drinking. The age disparity is most pronounced among women. Those aged 65 and over are 12 times more likely than those aged between 16 and 24 to drink on a near-daily basis according to data from the Office for National Statistics (ONS).

11 Mar 2012

ScienceInsider reports on Lancet letters regarding CDC Center for Global Health

In a letter published Wednesday in the Lancet, officials from the CDC refute "point by point" three letters previously published in the journal that were critical of the agency's Center for Global Health, ScienceInsider reports.

11 Mar 2012

Young children with SDB more likely to develop neurobehavioral problems

A study of more than 11,000 children followed for over six years has found that young children with sleep-disordered breathing are prone to developing behavioral difficulties such as hyperactivity and aggressiveness, as well as emotional symptoms and difficulty with peer relationships, according to researchers at Albert Einstein College of Medicine of Yeshiva University.

5 Mar 2012

Scientists discover how to enhance production of hepatocytes to repair damaged liver tissue

Scientists have shed light on how the liver repairs itself with research that could help develop drugs to treat liver disease.

4 Mar 2012

Induced hyperammonaemia increases daytime sleepiness in patients with cirrhosis

Italian and Swiss researchers confirm that induced hyperammonaemia significantly increases daytime sleepiness in patients with cirrhosis. The findings available in the March issue of Hepatology, a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases, show that higher blood levels of ammonia reduced the ability of cirrhotic patients to produce restorative sleep.

2 Mar 2012

FDA revises safety information on statin labels

The United States Food and Drug Administration (FDA) announced it is revising safety information on the labels of some statins (cholesterol lowering drugs).

1 Mar 2012