Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

Role of ethnicity in nonalcoholic fatty liver disease

The first study to examine nonalcoholic fatty liver disease (NAFLD) among different ethnic and racial groups in the United States finds that Hispanics may be at a higher risk of developing the condition. The study is published in Hepatology, the official journal of the American Association for the Study of Liver Diseases (AASLD). Published by John Wiley & Sons, Inc., Hepatology is available online via Wiley InterScience.

19 Jan 2005

Sildenafil restores cognitive function in rats after liver failure

A study involving rats reveals the mechanism responsible for learning impairment due to liver failure and shows that sildenafil restores cognitive function.

19 Jan 2005

Major partnership with National Institute of Allergy and Infectious Diseases for Narhex Life Sciences

Australian drug specialist Narhex Life Sciences, has announced a partnership with one of the world’s foremost US medical research centres to evaluate its protease inhibitor Nar DG 35 Prodrug for its activity against Hepatitis C and SARS viruses.

12 Jan 2005

Push for mandatory health warnings on all alcohol products

Australian Medical Association President, Dr Bill Glasson, said today the AMA is calling on the Australian Federal Government to legislate for health warnings on all alcohol products.

21 Dec 2004

Researchers discover clues to cirrhosis

Researchers at the University of Essex have found new biochemical indicators of cirrhosis in blood plasma which could help detect the disease in its early stages.

20 Dec 2004

A new study has found fatty liver disease in nearly one third of American adults in a large urban population sample

The prevalence of the disease varied significantly among ethnic groups. Hispanics had a higher prevalence than whites, while blacks had a lower prevalence than whites.

8 Dec 2004

Peripheral neuropathy in a patient with alcoholic cirrhosis is reversible

Organ damage that goes beyond the liver due to alcoholism is often seen as a barrier to liver transplantation, despite a lack of data on how a transplant affects these complications.

1 Dec 2004

T cells activated in the gut during inflammatory bowel disease can be re-routed to the liver and cause chronic liver disease

The authors explain this detour by showing that an attractant protein that normally directs T cells into the gut is aberrantly produced in the liver during PSC. T cells expressing the receptor for the protein are thus re-routed to the liver

29 Nov 2004

White Paper aims to reduce the number of people who smoke

Health Secretary John Reid today published Choosing Health – the Government’s White Paper on improving public health in England.

16 Nov 2004

Caspase levels associated with liver injury

Caspase activity in the sera of patients with chronic hepatitis C infection (HCV) may be a more sensitive measure of liver injury than conventional surrogate markers like aminotransferases, according to a new study published in the November 2004 issue of Hepatology.

8 Nov 2004

British Medical Association calls on Health Secretary to deliver tough action to protect the nation's health

The British Medical Association today (4 November 2004) calls on Health Secretary John Reid to deliver tough action to protect the nation's health, as he finalises the White Paper on Public Health for England.

4 Nov 2004

Program triples hepatitis B vaccination rates in targeted regions of rural China

The Bristol-Myers Squibb Foundation and the China Foundation for Hepatitis Prevention and Control (CFHPC) announced the results of a collaborative grassroots education and vaccination program designed to fight the spread of one of China's most pressing health problems -- hepatitis B.

1 Nov 2004

New approaches for the treatment of chronic hepatitis C

Data from two ongoing studies testing new approaches for the treatment of chronic hepatitis C was presented at the annual meeting of the American Association for the Study of Liver Diseases (AASLD) this afternoon.

1 Nov 2004

Pegasys with ribavirin combo may best for reducing hepatitis C viral levels

Interim study results indicate a certain drug combination treatment may suppress the hepatitis C virus more quickly than another.

1 Nov 2004

Teva Pharmaceuticals granted final approval for Ribavirin capsules

Teva Pharmaceutical Industries has announced that the U.S. Food and Drug Administration has granted final approval for the Company’s ANDA for Ribavirin Capsules, 200 mg. Shipment of this product is expected to begin immediately.

5 Oct 2004

Research to halt the progress of chronic liver disease

A University of Queensland researcher is working to halt the progress of chronic liver disease, which affects a quarter of million Australians.

22 Sep 2004

Severe hepatitis C recurrence is more common in transplants from living donors

Hepatitis C recurs with severity more often in individuals who receive liver transplants from living donors compared with those who get transplants from cadavers, according to a new study published in the September 2004 issue of Hepatology.

9 Sep 2004

FDA reinforces use of Sustiva in first-line HIV combination therapy

Bristol-Myers Squibb has announced that Sustiva® (efavirenz) has received approval from the U.S. Food and Drug Administration to include new long-term virologic and clinical data from BMS Study 006 in its prescribing information.

26 Aug 2004

Researchers have identified multiple changes in the gene-expression patterns of cells involved with tumor progression in liver cancer patients

Virginia Commonwealth University researchers have identified multiple changes in the gene-expression patterns of cells involved with tumor progression in liver cancer patients and in those with cirrhosis, which may help scientists predict a person’s risk of developing primary liver cancer.

25 Aug 2004

Diabetes and heart disease may stem from fat you can't see

Becoming fat brings conspicuous changes to the shape of the human body, but pioneering research in the Department of Medicine at Flinders University, Australia is working on the theory that the obvious "spare tyre" may not be the major culprit in fat-related diseases.

24 Aug 2004