Liver Transplantation News and Research

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Colorado researchers find lower vaccination rates among pediatric transplant patients

University of Colorado researchers have found lower vaccination rates among children who receive liver transplants, increasing the risk of sickness for those children, who already face significant health issues.

13 Nov 2019

Researchers use phage therapy to successfully treat alcoholic liver disease

Researchers have successfully used bacteriophage (phage) therapy to eliminate alcohol-related liver disease in an animal model.

13 Nov 2019

UC researcher finds new treatment option for liver transplant patients

A drug commonly used to treat both asthma and inflammatory bowel disease, budesonide, may also be useful as an anti-organ rejection medication for liver transplant patients leading to fewer serious side effects than the most commonly used therapy, according to a University of Cincinnati researcher.

9 Nov 2019

Natural language processing helps evaluate electronic messages from ESLD patients

Natural language processing, the technology that lets computers read, decipher, understand and make sense of human language, is the driving force behind internet search engines, email filters, digital assistants such as Amazon's Alexa and Apple's Siri, and language-to-language translation apps.

From Johns Hopkins Medicine 7 Nov 2019

Deaths from liver cancer increased 3-fold over 20 years in England

Liver cancer is rapidly moving up the cancer killer ranks in England, according to a new study that is to be presented at the 201th NCRI Cancer Conference on November 2, 2019. Both the number of new cases and the mortality rate from hepatocellular carcinoma (HCC), have tripled, over the period from 1997 to 2016. HCC is the most common form of liver cancer. Moreover, a quarter of these cases occur among the least privileged fifth of society.

3 Nov 2019

Cleveland Clinic successfully performs first laparoscopic living donor liver transplantation

Cleveland Clinic has successfully performed the Midwest's first purely laparoscopic living donor surgery for liver transplantation in an adult recipient.

30 Oct 2019

'Lab on a chip' technology may help find new treatments for NAFLD

Non-alcoholic fatty liver disease--the accumulation of liver fat in people who drink little or no alcohol--is increasingly common around the world, and in the United States, it affects between 30 and 40 percent of adults.

29 Aug 2019

HistoIndex, ILBS launch Center of Excellence to enhance NASH diagnostics and clinical trials

In a cross border collaboration, HistoIndex and the Institute of Liver & Biliary Sciences (ILBS) in New Delhi, India have jointly launched a Centre of Excellence to aid diagnostics and clinical trials focusing on NASH.

8 Aug 2019

Study shows how cannabis could be effective for both pain relief and insomnia

A new study has shown how cannabis could be an effective treatment option for both pain relief and insomnia, for those looking to avoid prescription and over the counter pain and sleep medications -including opioids.

2 Jul 2019

New study on viability of donated livers and its correlation with donor demographics

In a paper to be published in a forthcoming issue of TECHNOLOGY, a group of researchers from Harvard Medical School have done a study on the viability of donated livers and its correlation with donor demographics.

14 May 2019

Study finds identical alcohol relapse rates among liver transplant recipients regardless of sobriety period

For decades, patients with liver disease related to alcohol use have been told they must be sober for six months before they can get a liver transplant.

26 Apr 2019

Integrating AI to analyze imaging data allows early recognition of heart disease

Integrating artificial intelligence to analyze imaging data allows early recognition of heart disease, saving patients' time, money and, most importantly, lives.

17 Apr 2019

Study uncovers genetic variant associated with liver fibrosis in chronic hepatitis C patients

A new study from The Westmead Institute for Medical Research has identified a genetic variant associated with liver fibrosis (scarring) in chronic hepatitis C patients. This finding is a step toward reducing the number of patients requiring liver transplants.

3 Apr 2019

New strategy for potential treatment of HBV associated liver cancer

Researchers from Duke-NUS Medical School, Singapore General Hospital and Lion TCR have demonstrated that they were able to engineer HBV-specific T cells, a type of immune cells found in the body, to treat Hepatocellular carcinoma, a commonly occurring liver cancer.

28 Mar 2019

Researchers identify first genetic defect linked to biliary atresia

A nationwide consortium of researchers has identified the first genetic defect linked to biliary atresia, a mysterious liver disease that is the leading cause for liver transplantation in children.

5 Mar 2019

Researchers are developing and testing novel gene therapy to cure Crigler-Najjar syndrome

Crigler-Najjar syndrome affects about one in a million people at birth. Because of a defective gene, these individuals lack an essential enzyme in their liver to eliminate bilirubin, a toxic bile pigment that accumulates in all body tissues causing jaundice and potentially leading to irreversible and lethal neurological damage.

28 Feb 2019

Genetic defect linked to pediatric liver disease identified

Researchers from the University of Colorado Anschutz Medical Campus, in collaboration with several other institutions, have discovered a genetic defect linked to Biliary atresia, the most common pediatric cause of end-stage liver disease, and the leading indication for liver transplantation in children.

21 Feb 2019

Large-scale clinical trial begins to study liver transplantation between people with HIV

The first large-scale clinical trial to study liver transplantation between people with HIV has begun at clinical centers across the United States. The HOPE in Action Multicenter Liver Study will determine the safety of this practice by evaluating liver recipients for potential transplant-related and HIV-related complications following surgery.

15 Feb 2019

New acute porphyria treatment shows promising results in clinical study

Acute porphyria is a group of uncommon diseases that can cause severe, potentially life-threatening attacks of abdominal pain, nausea, vomiting and paralysis. Liver transplantation is currently the only effective treatment available for the most seriously afflicted patients.

7 Feb 2019

Largest description of ST3GAL5 deficiency combined using data from 104 individuals

Researchers have combined the largest description of ST3GAL5 deficiency using detailed natural history data from 104 individuals of Amish ancestry born between 1986 and 2017 with a definite or probable diagnosis of ST3GAL5 deficiency.

6 Feb 2019