Liver Transplantation News and Research

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Study uncovers previously unknown compensatory mechanism in liver disease

A team of researchers has uncovered a previously unknown compensatory mechanism found in liver disease.

28 Sep 2023

Fatty liver disease susceptibility: study identifies interaction between estrogen receptor and genetic variant in women

Researchers pursued evidence of whether the interaction between the patatin-like phospholipase domain-containing 3 p.I148M variant and the female sex at the genetic and molecular level explains why premenopausal women remain protected against fatty liver disease, while a rapidly progressive disease ensues in some peri- and postmenopausal women.

28 Sep 2023

Living donor liver transplantation improves waitlist outcomes in high-risk cirrhosis patients

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 17, entitled, "Availability of living donor optimizes timing of liver transplant in high-risk waitlisted cirrhosis patients."

26 Sep 2023

Keck School of Medicine researchers receive $12 million grant to study early liver transplantation

Alcohol-associated liver disease accounts for 50% of liver-related deaths, and its rates are rising worldwide.

24 Aug 2023

$9.57 million grant will support a clinical trial to study new treatment option for NAFLD

According to the National Institutes of Health, approximately 24% of adults in the United States have nonalcoholic fatty liver disease (NAFLD), an umbrella term for a range of liver conditions affecting people who drink little to no alcohol that can lead to cirrhosis, liver cancer and liver failure.

23 Aug 2023

New matching system enables world's first four-way liver exchange

In a breakthrough in liver transplantation that may lead to the ability to connect more living donors and patients, a new matching system designed by a team led by Boston College economists enabled the world's first four-way liver exchange and a cascade of additional matches, researchers reported recently in the American Journal of Transplantation.

22 Aug 2023

UCLA study finds new way to protect livers during transplantation

UCLA-led research describes the role that a protein called CEACAM1 plays in protecting the liver from injury during the transplantation process, potentially improving transplant outcomes.

2 Aug 2023

Study shows that anti-PTM antibodies are often present in autoimmune mediated liver disease

A recent study published in Frontiers in Medicine described anti-post-translational modification (PTM) antibodies in patients with autoimmune-mediated and cholestatic liver diseases (AILD).

31 Jul 2023

Proteins CEACAM1 and TIM-3 may help protect liver transplants

A new study identifies how certain proteins in the immune system interact leading to organ rejection. The study, which involved experiments on mice and human patients, uncovered an important communication pathway between two molecules called CEACAM1 (CC1) and TIM-3, finding that the pathway plays a crucial role in controlling the body's immune response during liver transplantation.

19 Jul 2023

Normothermic machine preservation shows promise in liver transplantation

A groundbreaking clinical trial comparing conventional low temperature storage of transplant donor livers with storage at physiological body temperature has revealed promising results for the evolution of liver transplantation.

17 Jul 2023

Washington University surgeons pioneer robotic liver transplantation

A surgical team from Washington University School of Medicine in St. Louis recently performed the first robotic liver transplant in the U.S. in May at Barnes-Jewish Hospital.

12 Jul 2023

Researchers identify a potential new drug for NASH-related fibrosis

Researchers at the University of California San Diego School of Medicine have led a study to examine a potential new treatment option for patients with nonalcoholic steatohepatitis (NASH)-related fibrosis.

26 Jun 2023

Targeting Phage Therapy 2023 showcased the progress and possibilities of phage therapy in future

The 6th World Congress on Targeting Phage Therapy 2023 that was held on June 1-2 in Paris, and gathered more than 150 attendees from 30+ different countries. Targeting Phage Therapy 2023 included more than 71 presentations between major talks, short orals, and posters.

20 Jun 2023

Study: Metabolic-associated fatty liver disease is increasing among U.S. adults

The percent of metabolic associated fatty liver disease (MAFLD), the leading global cause of liver disease, is increasing in U.S. adults, according to a study presented Friday at ENDO 2023, the Endocrine Society's annual meeting in Chicago, Ill.

17 Jun 2023

DIALIVE device may be a disease-modifying therapy for patients with acute-on-chronic liver failure

Acute-on-chronic liver failure (ACLF) occurs in 30% of hospitalized cirrhosis patients, leading to over one million deaths worldwide each year.

31 May 2023

Study sheds light on global disparities in mortality rates from liver disease

New research is shedding light on global disparities in mortality rates from late-stage liver disease, also called cirrhosis.

25 May 2023

Addition of palliative care services to cancer patients having surgery does not provide benefits

One of the most important advances in palliative care in oncology over the past 15 years has been the recognition that palliative care specialists can improve cancer patients' outcomes well before their end of life.

10 May 2023

Study shows link between liver transplant survivor's recovery and sociodemographic factors

The resilience and coping abilities of patients who've had liver transplants vary and change over time and are often linked to sociodemographic factors including income, race, and education, a study led by UT Southwestern Medical Center researchers shows.

27 Apr 2023

Novel amino acid compound treats nonalcoholic fatty liver disease in non-human primates

A recently developed amino acid compound successfully treats nonalcoholic fatty liver disease in non-human primates -; bringing scientists one step closer to the first human treatment for the condition that is rapidly increasing around the world, a study suggests.

10 Apr 2023

ChatGPT can help empower patients and improve health literacy for different populations

A new study by Cedars-Sinai investigators describes how ChatGPT, an artificial intelligence (AI) chatbot, may help improve health outcomes for patients with cirrhosis and liver cancer by providing easy-to-understand information about basic knowledge, lifestyle and treatments for these conditions.

7 Apr 2023