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Yin Yang 1 regulates early B cell development

A new paper in the May 15th issue of Genes & Development reveals how a protein called Yin Yang 1 regulates early B cell development.

17 May 2007

Scientists discover molecular mechanism that keeps HSV-1 activation restricted to a single gene for months or even years

By adulthood, most people have suffered at least one bout of painful cold sores brought on by the Herpes simplex virus 1, also known as HSV-1.

4 May 2007

Discovery of important clue to the susceptibility of individuals to Crohn's disease

Crohn's disease is a chronic relapsing inflammatory disorder of the intestinal tract that affects an estimated 0.15% of people in the developed world. Common symptoms include abdominal pain and diarrhea, but the disorder is often associated with debilitating clinical complications.

21 Apr 2007

Researchers identify genetic risk for type 1 diabetes

A discovery at the Barbara Davis Center for Childhood Diabetes has identified a genetic risk for type 1 diabetes three to four times higher than previously thought possible.

4 Sep 2006

Structural alterations in breast stromal and epithelial DNA

Researchers have uncovered a pattern of DNA damage in connective tissues in the human breast that could shed light on the early stages of breast cancer.

3 Aug 2006

First complete kit for whole genome amplification and labeling

Kreatech Biotechnology BV has announced the launch of the "Genome-pULSe, arrayCGH Whole Genome Amplification and Labeling Kit" the latest addition to their product portfolio for arrayCGH analysis.

24 Jul 2006

Genetic cause of hearing loss in aging

Researchers at Indiana University School of Medicine have taken a step toward understanding the genetics that make people more susceptible to the loss of hearing as they age.

17 May 2006

Neurons can produce Alzheimer's-linked apolipoprotein E

A question long debated among Alzheimer's disease researchers has been definitively answered by scientists at the Gladstone Institute of Neurological Disease in San Francisco.

10 May 2006

"Junk" RNA regulates important cellular processes

It has been known for a long time that much of a cell’s RNA stems from DNA regions called intergenic spacers (IGS) that lie between two genes and do not code for proteins.

9 May 2006

Blood cancers may be caused by inactivation of a "tumor suppressor" gene

The discovery of a gene, called PRDM1, as a tumor suppressor sheds new light on the cause - and possible treatment - of diffuse large B-cell lymphomas (DLBCLs), a cancer of the blood's B-lymphocytes. DLBCLs comprise about 30 percent of non-Hodgkin's lymphomas.

25 Apr 2006

Researchers identify the role of a protein in hemoglobin gene silencing

Virginia Commonwealth University Massey Cancer Center researchers have identified the role of a protein in hemoglobin gene silencing that may one day be a potential target for the treatment of genetic blood disorders like sickle-cell anemia and beta-thalassemia on the molecular level.

11 Apr 2006

Weill Cornell researchers identify tumor-suppressor gene important to diffuse large B-cell lymphomas

Inactivation of a "tumor suppressor" gene could be a major cause of a class of blood cancers called diffuse large B-cell lymphomas, reports a team of researchers at the Weill Medical College of Cornell University.

30 Mar 2006

Key genes identified that enable tuberculosis infection to spread

Scientists in India, led by a Howard Hughes Medical Institute (HHMI) international research scholar, have identified five key genes that enable Mycobacterium tuberculosis to acquire the iron it needs to sustain growth and promote infection

5 Feb 2006

Detecting MRSA outbreaks

German researchers have proposed an automated DNA sequence-based early warning system to detect methicillin-resistant Staphylococcus aureus (MRSA) outbreaks in hospitals, which they say could replace traditional slower techniques.

10 Jan 2006

Chromosome link found between alcohol addiction and smoking

Scientists have found in a study of tobacco users that their drinking behavior is linked to some of the same chromosome regions associated with alcohol addiction.

22 Dec 2005

New study shows tiny RNAs intimately associated with cancer

In discoveries that may open a new chapter in understanding and diagnosing cancer, Howard Hughes Medical Institute (HHMI) investigators and their colleagues have established that tiny microRNAs provide a novel genetic route to the initiation of some forms of cancer.

9 Jun 2005

New technique will enhance understanding of little-understood vision phenomenon

Look at something red in the room, and you'll be more likely to notice something red out of the corner of your eye, elsewhere in the room. Researchers have known that this "implicit attentional selection" is outside conscious control and that we are unaware of its functioning.

1 Jun 2005

Fertility clinics across the United States already ensure that donated sperm is safe, regardless of the sexual orientation of the donor

The American Fertility Association (AFA) disagrees with the Food and Drug Administration's (FDA) sperm donation guidelines, which take effect on May 25, 2005.

12 May 2005

Most comprehensive genome-wide experimental analyses of sense-antisense transcripts to date

A team of scientists led by Dr. Kuniya Abe from the RIKEN BioResource Center in Japan has performed one of the most comprehensive genome-wide experimental analyses of sense-antisense transcripts to date. Their findings are published in the April issue of the journal Genome Research.

15 Mar 2005

New primate-specific gene family that spans about 10% of human chromosome 2

A team of scientists led by Peer Bork, Ph.D., Senior Bioinformatics Scientist at the European Molecular Biology Laboratory, report today in the journal Genome Research that they have identified a new primate-specific gene family that spans about 10% of human chromosome 2.

13 Feb 2005