Low Density Lipoprotein (LDL) News and Research

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Too much red meat in diet can shorten lifespan: Study

According to Harvard researchers, publishing this week in the Archives of Internal Medicine, the risk of dying at an early age - from heart disease, cancer, or any other cause, rises in step with red-meat consumption. Eating too much red meat, which is high in saturated fat and cholesterol, has long been seen as unhealthy, especially for the heart. The new study, however, is the first to estimate the effect of red meat in diet on a person's lifespan.

13 Mar 2012

FDA revises safety information on statin labels

The United States Food and Drug Administration (FDA) announced it is revising safety information on the labels of some statins (cholesterol lowering drugs).

1 Mar 2012

Nicotine can contribute to atherosclerosis

Cigarette smoke has long been considered the main risk factor for heart disease. But new research from Brown University in Providence, R.I., shows that nicotine itself, a component of cigarette smoke, can contribute to the disease process by changing cell structure in a way that promotes migration and invasion of the smooth muscle cells that line blood vessels.

24 Feb 2012

Researchers discover new evidence on how cholesterol transfers from HDLs to LDLs

Researchers with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) have found new evidence to explain how cholesteryl ester transfer protein (CETP) mediates the transfer of cholesterol from "good" high density lipoproteins (HDLs) to "bad" low density lipoproteins.

21 Feb 2012

The 'nutritional magic' behind soy's heart health benefits

Nutrition science has regarded soy as a superfood with many health benefits for decades. In fact, "25 grams of soy protein per day, as part of a diet low in saturated fat and cholesterol, may reduce the risk of heart disease," according to the FDA.

18 Feb 2012

Regeneron reports total revenues of $123.0M for fourth quarter 2011

Regeneron Pharmaceuticals, Inc. announced financial and operating results for the fourth quarter and full year 2011 and provided an update on development programs.

13 Feb 2012

Coronary patients with low levels of anti-PC at greater risk of complications

Coronary patients with low levels of an immune system antibody called anti-PC, which neutralises parts of the "bad" cholesterol, run a greater risk of suffering complications following an acute cardiac episode and thus of premature death.

6 Feb 2012

Postmenopausal women at higher risk of stroke than they think

A new study by researchers at NYU Langone Medical Center and colleagues found that traditional risk factors for stroke - such as high cholesterol - are not as accurate at predicting risk in postmenopausal women as previously thought. Instead, researchers say doctors should refocus their attention on triglyceride levels to determine which women are at highest risk of suffering a devastating and potentially fatal cardiovascular event.

3 Feb 2012

Strong link between triglyceride levels and ischemic stroke in older women

In a surprising finding with significant implications for older women, researchers at Albert Einstein College of Medicine of Yeshiva University and NYU School of Medicine have found that high levels of triglycerides (blood fats) are the strongest risk factor for the most common type of stroke in older women – more of a risk factor than elevated levels of total cholesterol or of low-density lipoprotein (LDL) cholesterol.

3 Feb 2012

Study: Electronic health records can improve care, outcomes in patients with type 2 diabetes

Use of electronic health records shows promise for improving care and outcomes in patients with type 2 diabetes, but still has considerable room for improvement, according to a new study in the journal Health Services Research.

30 Jan 2012

Viewpoints: The 'need' to repeal CLASS; Squaring Romney's poverty and tax promises

As a physician, I treated hundreds of patients who needed long-term care, including ones with Alzheimer's. More than 13.5 million seniors could have this disease by 2040. Middle-class families remain dangerously unprepared for these costs. Some people will likely spend more than $100,000 on care. The fictional CLASS daily benefit of $50 per day won't cover this. I urge my House and Senate colleagues to support this CLASS repeal.

19 Jan 2012

Spherix completes SPX-106 28-day rat toxicology study

Spherix Incorporated – an innovator in biotechnology for therapy in diabetes, metabolic syndrome and atherosclerosis, and provider of technical and regulatory consulting services to food, supplement, biotechnology and pharmaceutical companies, today reported the successful completion of its 28-day rat toxicology study of its drug candidate, SPX-106.

11 Jan 2012

Natural options against weight gain, sugar cravings, and insulin resistance

The holidays have come and gone, but many of us may still be battling intense sweet cravings leftover from the season's festivities. Excessive sugar cravings can be a sign that your blood glucose levels are out of balance which, if left unchecked, can lead to insulin resistance and Metabolic Syndrome, also known as "Pre-Diabetes."

11 Jan 2012

Physiological impact of hurt feelings

Working up your courage to ask someone to be your Valentine? Science is uncovering the reason why we fear social rejection: Not only does it dash our hopes, it actually puts the brakes on our heart. Specifically, learning that someone doesn't like you triggers a drop in heart rate.

11 Jan 2012

First study to elucidate how statins reduce activation of abnormal blood clotting

People with high cholesterol are at risk of heart attack and stroke because atherosclerotic plaques within their arteries can rupture triggering the formation of a blood clot called an occlusive thrombus that cuts off the blood supply to their heart or brain.

5 Jan 2012

Positive preliminary results from Alnylam's Phase I ALN-PCS trial on severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today the achievement of positive preliminary results from its ongoing clinical trial of ALN-PCS, an RNAi therapeutic targeting PCSK9 for the treatment of severe hypercholesterolemia.

5 Jan 2012

Veloxis, Athena partner to establish competitive presence for AtorFen in emerging markets

Veloxis Pharmaceuticals and Athena Drug Delivery Solutions Pvt. Ltd. today announced an alliance whereby Athena will obtain exclusive rights in certain emerging market territories to manufacture and, with third parties, develop, register and commercialize Veloxis' AtorFen (Fenofibrate Atorvastatin fixed dose combination).

23 Dec 2011

Faulty lipid metabolism may cause MS, says forensic anthropologist

An article to be published in the December 2011 issue of The Quarterly Review of Biology argues that multiple sclerosis, long viewed as primarily an autoimmune disease, is not actually a disease of the immune system.

23 Dec 2011

Lean beef can contribute to heart-healthy diet

Lean beef can contribute to a heart-healthy diet in the same way lean white meats can, according to nutritional scientists.

22 Dec 2011

The Academy of Nutrition and Dietetics to expand coverage of MNT

The Academy of Nutrition and Dietetics has prepared a request to submit to the Centers for Medicare and Medicaid Services (CMS) to expand coverage of medical nutrition therapy (MNT) for specific diseases, including hypertension, obesity, and cancer, as part of the CMS National Coverage Determination (NCD) Process.

19 Dec 2011