Low Density Lipoprotein (LDL) News and Research

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New test measures blood concentrations of plasma ceramides to predict risk for heart attacks, strokes

A new type of blood test may help physicians identify which patients with and without evidence of coronary blockages are at risk for heart attacks and strokes.

10 Mar 2017

SLU study findings suggest new method to suppress LDL cholesterol

In a paper published in Biochemical Pharmacology, Saint Louis University researchers examined the way a nuclear receptor called REV-ERB is involved in regulating cholesterol metabolism.

6 Mar 2017

UAB researchers developing new peptide that may help combat familial hypercholesterolemia

Researchers at the University of Alabama at Birmingham are developing and testing a new peptide that they hope will lead to better treatment options for familial hypercholesterolemia.

22 Feb 2017

American Heart Month: Time to know foods that protect cardiac health

February is American Heart Month, and it is an important time to be informed on the most beneficial foods and nutrients to maintain a heart-healthy diet.

8 Feb 2017

Reducing cholesterol to level of newborn baby lowers cardiovascular disease risk, research finds

Reducing our cholesterol levels to those of a new-born baby significantly lowers the risk of cardiovascular disease, according to new research.

16 Dec 2016

Study shows ancient grain varieties may help reduce risk factors for CVD

Eating bread made with ancient grains as part of a healthy diet could help lower cholesterol and blood glucose levels—leading risk factors for heart attack and stroke—according to new research published in the International Journal of Food Sciences and Nutrition.

28 Sep 2016

Scientists identify molecule in liver cells that regulates release of fats into the bloodstream

ETH researchers have discovered a molecule in liver cells that controls the release of fat into the bloodstream. This "lock keeper" is present in large quantities in overweight people and leads indirectly to vascular narrowing.

28 Sep 2016

Seeds of tropical shrub guarana contain ten times more amount of catechins than green tea

The millions of people who consume green tea all over the world benefit from the catechins it contains.

22 Aug 2016

Accelerated cardiovascular risk in patients with FH phenotype

Patients with levels of low-density lipoprotein cholesterol normally seen in familial hypercholesterolaemia have the cardiovascular risk of someone decades older than they are, shows a population-based study.

4 Jul 2016

Older adults with high LDL-C live longer than peers with low levels of same cholesterol, say experts

A University of South Florida professor and an international team of experts have found that older people with high levels of a certain type of cholesterol, known as low-density lipoprotein (LDL-C), live as long, and often longer, than their peers with low levels of this same cholesterol.

27 Jun 2016

Real-world analysis questions very low LDL targets

Patients treated for hypercholesterolaemia in clinical practice may not derive additional benefit from very intensive statin treatment, say researchers.

22 Jun 2016

Raised lipoprotein(a) could account for a quarter of FH cases

High levels of lipoprotein(a) could account for a substantial proportion of cases of familial hypercholesterolaemia, a large study shows.

20 May 2016

First generic version of Crestor gets FDA approval

The U.S. Food and Drug Administration today approved the first generic version of Crestor (rosuvastatin calcium) tablets.

30 Apr 2016

Cholesterol drug evacetrapib fails to reduce risk of cardiovascular events

Despite lowering low-density lipoprotein (LDL), known as "bad" cholesterol, while markedly increasing levels of high-density lipoprotein (HDL), or "good" cholesterol, a large clinical trial to investigate the cholesterol drug evacetrapib was discontinued early after a preliminary analysis showed it did not reduce rates of major adverse cardiovascular events, according to research presented at the American College of Cardiology's 65th Annual Scientific Session.

4 Apr 2016

Lots of 'good' cholesterol may be bad

Recent research has identified a genetic mutation that prevents high-density-lipoprotein (HDL) cholesterol from being taken up by cells.

11 Mar 2016

PCSK9-inhibitor drugs: A game-changer for individuals with extremely high cholesterol levels

A 59-year-old heart patient with dangerously high levels of cholesterol that could not be adequately reduced by statin drugs now has near-normal cholesterol levels, thanks to a new class of drugs that grew out of work done by UT Southwestern Medical Center researchers.

27 Feb 2016

Weight loss programs that provide healthy fats have similar impacts on pound-shedding

A University of California, San Diego School of Medicine study finds that weight loss programs that provide healthy fats, such as olive oil in the Mediterranean diet, or a low-fat, high-carbohydrate diet have similar impacts on pound-shedding.

29 Jan 2016

Repatha (evolocumab) injection gets FDA approval for high cholesterol

The U.S. Food and Drug Administration today approved Repatha (evolocumab) injection for some patients who are unable to get their low-density lipoprotein (LDL) cholesterol under control with current treatment options.

9 Oct 2015

Novel approach to reduce 'bad' lipids in blood circulation

Xian-Cheng Jiang, PhD, professor of cell biology at SUNY Downstate Medical Center, has led a study identifying a new approach for lowering "bad" lipids in blood circulation, a critical means to combat devastating cardiovascular diseases such as atherosclerosis. The research was published in the online edition of Gastroenterology.

3 Sep 2015

FDA approves Praluent (alirocumab) Injection for treatment of patients with high LDL cholesterol

Regeneron Pharmaceuticals, Inc. and Sanofi today announced that the U.S. Food and Drug Administration approved Praluent (alirocumab) Injection, the first FDA-approved treatment in a new class of drugs known as PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors.

25 Jul 2015