Lung Disease News and Research

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Novartis QAB149 receives FDA Pulmonary-Allergy Advisory Committee approval for COPD

An advisory committee recommended today that the Food and Drug Administration (FDA) approve QAB149 (indacaterol) 75 mcg in the US as a once-daily long-term maintenance bronchodilator treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.

9 Mar 2011

New discovery in childhood respiratory disease

Researchers have identified a critical part of the process by which one of the world's most common and dangerous early childhood infections, respiratory syncytial virus, causes disease.

8 Mar 2011

EC grants marketing authorization for InterMune's Esbriet to treat IPF

InterMune, Inc. today announced that the European Commission has granted marketing authorization for Esbriet. Esbriet is indicated in adults for the treatment of mild to moderate idiopathic pulmonary fibrosis, a progressive and fatal lung disease.

3 Mar 2011

FDA approves roflumilast to treat COPD

The U.S. Food and Drug Administration approved roflumilast, a pill taken daily to decrease the frequency of flare-ups or worsening of symptoms from severe chronic obstructive pulmonary disease.

1 Mar 2011

FDA approves Forest Labs' Daliresp to treat COPD

Forest Laboratories, Inc. announced today that Daliresp was approved by the U.S. Food and Drug Administration as a treatment to reduce the risk of chronic obstructive pulmonary disease exacerbations in patients with severe COPD associated with chronic bronchitis and a history of exacerbations.

1 Mar 2011

Acute viral infection does not appear to cause exacerbation of IPF

Acute viral infection does not appear to be a primary cause of acute exacerbation of idiopathic pulmonary fibrosis, a progressive, deadly disease resulting in thickening and scarring of the lungs, according to a study conducted by researchers from the U.S., Korea and Japan.

28 Feb 2011

Single donor gifts lungs for two lung transplants

The University of Michigan Transplant Center celebrated a milestone recently, performing its 500th lung transplant. But there's much more to this story than a number.

17 Feb 2011

Obesity and knee osteoarthritis will lead to loss of 86 million healthy years of life

An estimated 10 million Americans suffer from knee osteoarthritis (OA), making it one of the most common causes of disability in the US. Due to obesity and symptomatic knee OA, Americans over the age of 50 will together lose the equivalent of 86 million healthy years of life, concluded researchers at Brigham and Women's Hospital (BWH), who investigated the potential gains in quality and quantity of life that could be achieved averting losses due to obesity and knee OA.

16 Feb 2011

New Rush clinic brings trained clinicians to care for patients with pulmonary hypertension

Cardiologists and pulmonologists at Rush University Medical Center have teamed up to provide a new and better approach to treating patients with pulmonary hypertension, a disease affecting the heart and lungs. The new Rush Pulmonary Hypertension Clinic brings together a multidisciplinary team of clinicians with specialized training to care for patients with this very complex disease.

16 Feb 2011

Combined chemotherapy and radiation therapy effective against Hodgkin's lymphoma, in the short term

Modern treatment for early stage Hodgkin's lymphoma is highly effective, leaving most patients with no evidence of cancer. However, experts differ on the best approach: Is chemotherapy enough or does adding radiation therapy improve the outcome?

16 Feb 2011

Genetic proof for anti-cancer properties of antioxidants and autophagy inhibitors

Researchers from Jefferson's Kimmel Cancer Center have genetic evidence suggesting the antioxidant drugs currently used to treat lung disease, malaria and even the common cold can also help prevent and treat cancers because they fight against mitochondrial oxidative stress-a culprit in driving tumor growth.

16 Feb 2011

Study shows beneficial anti-fibrotic effects of Pentraxin-2 in idiopathic pulmonary fibrosis

Promedior, Inc., a clinical stage biotechnology company developing novel therapies to treat fibrotic and inflammatory diseases, announced today the publication of collaborative research in the International Journal of Biochemistry and Cell Biology entitled, "TGF-beta driven lung fibrosis is macrophage dependent and blocked by Serum amyloid P."

14 Feb 2011

Study: Leptin resistance may help prevent ARDS, ALI development in patients with type II diabetes

Resistance to leptin, a protein that plays a key role in regulating metabolism and appetite, may help prevent the development of acute respiratory distress syndrome and acute lung injury in individuals with type II diabetes, according to a study conducted by researchers in Chicago.

13 Feb 2011

Study reveals beneficial anti-fibrotic effects of Pentraxin-2 in TGFβ1-induced lung disease

11 Feb 2011

Nutritional deficiencies among indigenous populations: two studies

They find iodine deficiency for the first time among an Aboriginal population in the NT. This deficiency was previously thought to occur only in the nation’s south-eastern states. The study involved nearly 400 teenagers of aboriginal origin living in remote as well as urban areas of the Darwin Health Region, which covers 120,000 km-square of the top end of the NT.

7 Feb 2011

Most Canadians want to do more to support cancer research

When it comes to cancer research, Canadians want to do more. A national survey released today in advance of World Cancer Day shows that more than half of Canadians 35 to 69 years of age feel cancer should be a top priority for health research. However, the survey also shows that a similar number do not know how to get involved in a way that could be helpful to other people.

4 Feb 2011

Rolling back Clean Air Act has life and death stakes

The Trust for America's Health warns that Chairman Fred Upton's (R-MI) draft bill could undermine the Clean Air Act and thereby harm millions of Americans.

4 Feb 2011

First blood-based diagnostic test for LAM

Circadian Technologies has announced today that in conjunction with Cincinnati Children's Hospital Medical Center it has begun offering its LAM diagnostic, which is offered as a laboratory test compliant with CAP (College of American Pathologists) /CLIA regulations.

2 Feb 2011

Vitamin D deficiency linked to lung disease, poor lung function: Study

For the study lead researcher Dr. Graeme Zosky a research fellow at the Telethon Institute for Child Health Research in Subiaco, WA, compared two-week-old mice with vitamin D deficiency to normal mice. He noted that mice with a vitamin D deficiency had weaker lungs and that the difference was substantial.

1 Feb 2011

News briefs from February issue of journal Chest

New research shows that vitamin D deficiency is prevalent among patients with interstitial lung disease (ILD), with the largest prevalence seen in patients with concurrent connective tissue disease (CTD).

1 Feb 2011

Lung Disease News and Research

Novartis QAB149 receives FDA Pulmonary-Allergy Advisory Committee approval for COPD

New discovery in childhood respiratory disease

EC grants marketing authorization for InterMune's Esbriet to treat IPF

FDA approves roflumilast to treat COPD

FDA approves Forest Labs' Daliresp to treat COPD

Acute viral infection does not appear to cause exacerbation of IPF

Single donor gifts lungs for two lung transplants

Obesity and knee osteoarthritis will lead to loss of 86 million healthy years of life

New Rush clinic brings trained clinicians to care for patients with pulmonary hypertension

Combined chemotherapy and radiation therapy effective against Hodgkin's lymphoma, in the short term

Genetic proof for anti-cancer properties of antioxidants and autophagy inhibitors

Study shows beneficial anti-fibrotic effects of Pentraxin-2 in idiopathic pulmonary fibrosis

Study: Leptin resistance may help prevent ARDS, ALI development in patients with type II diabetes

Study reveals beneficial anti-fibrotic effects of Pentraxin-2 in TGFβ1-induced lung disease

Nutritional deficiencies among indigenous populations: two studies

Most Canadians want to do more to support cancer research

Rolling back Clean Air Act has life and death stakes

First blood-based diagnostic test for LAM

Vitamin D deficiency linked to lung disease, poor lung function: Study

News briefs from February issue of journal Chest

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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