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Inhaled growth hormone safe for children deficient in this key protein

A multi-center clinical trial led by a Riley Hospital for Children endocrinologist has found that inhaled growth hormone (GH) is well tolerated by children with GH deficiency and that this easy-to-use method can, over a one-week period, safely deliver GH to the blood stream. In addition to having implications for those who need GH, this first pediatric study of administering it through the lungs may also help researchers interested in using this convenient method for effectively delivering other types of medications to children.

28 Jun 2009

Nanoparticle-mediated targeting of MAPK signaling predisposes tumor to chemotherapy

An interdisciplinary team of researchers at Brigham and Women's Hospital and the Harvard-Massachusetts Institute of Technology (MIT) Division of Health Sciences and Technology has demonstrated a better way to deliver cancer drugs directly to tumors.

28 Jun 2009

Migraines with aura in middle age associated with late-life brain lesions

Women who suffer from migraine headaches in middle age accompanied by neurological aura (visual disturbances, dizziness or numbness that can precede migraines) are more likely to have damage to brain tissue in the cerebellum later in life, according to a study by researchers at the National Institute on Aging (NIA) of the National Institutes of Health, the Uniformed Services University of the Health Sciences and the Icelandic Heart Association in Reykjavik.

23 Jun 2009

Discovery of potent metastasis inhibitor

Researchers at Children's Hospital Boston have isolated a potent inhibitor of tumor metastasis made by tumor cells, one that could potentially be harnessed as a cancer treatment.

23 Jun 2009

Direct link found between smoking and brain damage

New research which suggests a direct link between smoking and brain damage will be published in the July issue of the Journal of Neurochemistry. Researchers, led by Debapriya Ghosh and Dr Anirban Basu from the Indian National Brain Research Center (NBRC), have found that a compound in tobacco provokes white blood cells in the central nervous system to attack healthy cells, leading to severe neurological damage.

23 Jun 2009

Six 'major health agencies' form alliance to address chronic diseases in developing countries

A group of "major health agencies" from Australia, Canada, China, the U.K. and the U.S., which "together control 80 percent of the world's public health-research funding," have joined together to form the Global Alliance for Chronic Diseases (GACD) to combat chronic diseases in developing countries, Time reports (Walsh, Time, 6/16).

17 Jun 2009

Income, education, important factors in heart disease risk

Doctors who ignore the socioeconomic status of patients when evaluating their risk for heart disease are missing a crucial element that might result in inadequate treatment, according to a University of Rochester Medical Center study published in the June 2009 American Heart Journal.

16 Jun 2009

Dilon Technologies delivers enhanced imaging capabilities

Dilon Technologies, Inc., the leader in molecular breast imaging, today announced the release of the newest Dilon 6800 Software update including enhancements for both breast and general nuclear medicine applications image processing. The new software functionalities complement the Slant15 Collimator for breast imaging and the Low Energy High-Resolution (LEHR) Collimator for general nuclear medicine applications, both released earlier this year as purchase options for the Dilon 6800 gamma camera.

16 Jun 2009

Cannabis smoke damages DNA – cancer risks

A new study published by University of Leicester researchers has found "convincing evidence" that cannabis smoke damages DNA in ways that could potentially increase the risk of cancer development in humans.

16 Jun 2009

Immune system’s role in breast cancer

Researchers working with Dr Marcus Schmidt in the Department of Obstetrics and Gynecology at the University Medical Center Mainz have unlocked the key to the immune system's significance in cases of breast cancer, thus identifying its long-neglected role in the prognosis of the disease.

16 Jun 2009

RNA snippet reduces the spread of aggressive breast cancer

A low cellular level of a tiny fragment of RNA appears to increase the spread of breast cancer in mouse models of the disease, according to researchers at Whitehead Institute for Biomedical Research.

15 Jun 2009

Discovery shows potential for new severe asthma treatment

Scientists from King's College London and Imperial College London believe they have discovered a key element in the development of chronic asthma. Their research has been published in a new paper in the journal Proceedings of the National Academy of Sciences to explain why the structure and function of asthmatic airways are changed or ''remodelled'' and how this contributes to chronic asthma.

15 Jun 2009

Research finds Tamiflu and Relenza relatively safe for use in pregnancy

With the H1N1 flu outbreak now elevated to pandemic level, a new article in CMAJ (Canadian Medical Association Journal) reports that oseltamivir (Tamiflu) and zanamivir (Relenza) are relatively safe drugs for use in pregnant and breast-feeding women.

15 Jun 2009

Men hit by 'inexplicable' greater cancer death risk

Men are almost 40 per cent more likely than women to die from cancer, reveals a report published today (Monday) by the National Cancer Intelligence Network (NCIN) and Cancer Research UK together with the Men's Health Forum to mark Men's Health Week.

14 Jun 2009

Senate passes landmark bill: FDA to regulate tobacco

The New York Times reports that "more than four decades after the surgeon general declared smoking a health hazard, the Senate on Thursday cleared the final hurdle to empowering federal officials to regulate cigarettes and other forms of tobacco for the first time.

13 Jun 2009

Waste disposal protein key to cancer tumor suppression in autophagy

"Taking out the trash" takes on a whole new meaning, as investigators at The Cancer Institute of New Jersey (CINJ) and Rutgers, The State University of New Jersey, have discovered that a waste disposal protein is the key to cancer tumor suppression in a process known as autophagy. CINJ is a Center of Excellence of UMDNJ-Robert Wood Johnson Medical School.

13 Jun 2009

90 per cent of the world's population won't have access to antivirals in pandemic - generic drugs may help though

Almost 90 per cent of the world's population will not have timely access to affordable supplies of vaccines and antiviral agents in the current influenza pandemic, but it is possible that inexpensive generic drugs that are readily available, even in developing countries, could save millions of lives.

13 Jun 2009

Senate approves legislation to give the FDA power to regulate tobacco

The Senate overwhelmingly approved legislation today that gives the Food and Drug Administration regulatory power to limit nicotine in cigarettes, "drastically curtail" advertising and "ban candied tobacco products" aimed at the young, The Associated Press reports.

11 Jun 2009

Study reveals publics’ ignorance of anatomy

A study of patients and members of the public has shown that most lack even basic knowledge of human anatomy. The research, featured in the open access journal BMC Family Practice, found that people were generally incapable of identifying the location of major organs, even if they were currently receiving relevant treatment.

11 Jun 2009

New drug for muscle degenerating diseases shows great promise

A new drug being studied for the treatment of muscle degenerating diseases has shown promising results. According to a study published today in the British Journal of Pharmacology, Debio 025 is as effective as current drugs but, crucially, does not cause unwanted immunosuppressive effects.

10 Jun 2009