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Ovarian cancers detected early may be less aggressive, questioning effectiveness of screening

The biology of ovarian cancers discovered at an early stage may render them slower growing and less likely to spread than more aggressive cancers, which typically are discovered in an advanced stage, according to a study led by investigators in the Duke Comprehensive Cancer Center.

24 Mar 2009

Gilead commences phase II trial of Cicletanine for pulmonary arterial hypertension

Gilead Sciences, Inc. has announced that it has begun enrolling patients in a Phase II clinical trial of cicletanine hydrochloride (cicletanine), an oral agent in development for the treatment of pulmonary arterial hypertension (PAH).

24 Mar 2009

FDA approves new indication for Wyeth's Tygacil (tigecycline)

Wyeth Pharmaceuticals, a division of Wyeth has announced that the U.S. Food and Drug Administration (FDA) approved Tygacil (tigecycline), for the treatment of adult patients with community-acquired bacterial pneumonia (CABP) caused by susceptible strains of indicated pathogens.

24 Mar 2009

New insights may help HIV and cancer patients

Important progress in understanding the function of tetherin, known to have both anti-cancer and anti-viral properties, has been made by researchers at the University of Bristol.

24 Mar 2009

New strategy for fighting persistent bacterial infections

Researchers at National Jewish Health have discovered a promising strategy for destroying the molecular scaffolding that can make Pseudomonas bacterial infections extremely difficult to treat in cystic fibrosis patients, wearers of contact lenses, and burn victims.

23 Mar 2009

Social isolation makes strokes more deadly in mice

New research in mice suggests that social isolation may promote more damaging inflammation in the brain during a stroke.

23 Mar 2009

More cancer patients cured according to new data on cancer survival in Europe

New data and analyses from a long-running study of cancer survival in Europe have shown that the number of people actually cured of cancer - rather than just surviving for at least five years after diagnosis - is rising steadily.

23 Mar 2009

Licorice may offer a new approach to preventing colorectal cancer

A chemical component of licorice may offer a new approach to preventing colorectal cancer without the adverse side effects of other preventive therapies, Vanderbilt University Medical Center researchers report.

23 Mar 2009

Environmental cardiology - the relationship between air pollution and heart disease

We are used to thinking of heart disease as a product of genetic factors or lifestyle choices, such as what we eat and how much we exercise.

23 Mar 2009

Family history linked to increased risk of venous thrombosis

Children and siblings of those with venous thrombosis, or blood clots in the veins, appear to have more than double the risk of developing the condition than those without a family history, according to a report in the March 23 issue of Archives of Internal Medicine.

23 Mar 2009

Common gene variations found to influence risk factor for sudden cardiac death

A new study has identified several common genetic variants related to a risk factor for sudden cardiac death.

23 Mar 2009

Injected luminol glows blue revealing immune cells' misdeeds

Detectives on television shows often spray crime scenes with a compound called luminol to make blood glow.

22 Mar 2009

Biopsy of recurrent breast cancer can alter treatment

For women with recurrent breast cancer, the treatment the doctor chooses is usually based on the properties of their original breast cancer.

20 Mar 2009

Research could lead to potential new drugs for treating asthma

The American Asthma Foundation announced that a significant research discovery they funded has been licensed by a leading biotech company.

20 Mar 2009

Prostate cancer expert say keep screening in face of contradicting data

New data evaluating the impact of screening on mortality provides mixed messages on the value of prostate cancer screening.

20 Mar 2009

Superbug complicates treatment of infections in cystic fibrosis

The unexpected behaviour of a family of "superbugs" called the Burkholderia cepacia complex (Bcc) could have implications for the treatment of cystic fibrosis (CF) patients.

17 Mar 2009

Study tracks increasing use of CT on pregnant women

Researchers have found that over a 10-year period radiologic exams on pregnant women have more than doubled, according to a study published in the online edition of Radiology.

17 Mar 2009

MicroRNA undermines tumor suppression

Scientists at the Whitehead Institute for Biomedical Research and the National University of Singapore have discovered the first microRNA (miRNA) capable of directly tamping down the activity of the well known tumor-suppressor gene, p53, While p53 functions to prevent tumor formation, the p53 gene is thought to malfunction in more than 50% of cancerous tumors.

17 Mar 2009

Lung cancer: Molecular scissors determine therapy effectiveness

In the past few years, a number of anti-cancer drugs have been developed which are directed selectively against specific key molecules of tumor cells.

17 Mar 2009

Telemedicine expansion gives parents more options

Parents who need after-hours healthcare for their children don't need to turn to the Emergency Department (ED) for common childhood illnesses, such as ear infections and sore throats.

17 Mar 2009