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Clinical trial shows reduction in mortality for children with severe Langerhans cell histiocytosis

A new international study finds that introducing an increased intensity of chemotherapy in children with severe Langerhans cell histiocytosis (LCH) can reduce the mortality rate for this disorder by as much as 20 percent when the patient demonstrates a rapid response to such treatment.

3 Mar 2008

Smoking from a hookah - harmful and addictive

A new fad among college students and other young people - smoking from a hookah - is raising public health concerns.

1 Mar 2008

New guidelines for von Willebrand disease

The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health, has issued the first clinical guidelines in the United States for the diagnosis and management of von Willebrand Disease (VWD), the most common inherited bleeding disorder.

1 Mar 2008

Genetic factors in smoking also increase risk of chronic bronchitis

Smoking is a known risk factor for respiratory diseases like chronic bronchitis, but genes also play a significant role in its development, according to researchers in Sweden, who studied more than 40,000 Swedish twins to determine the extent to which behavior, environment and genes each play a role ion the development of chronic bronchitis.

1 Mar 2008

Congestion charge has increased life expectancy of Londoners

The Central London Congestion Charging Scheme (CCS) has led to a modest increase in the life expectancy of Londoners, according to a joint study by King's College, London and the London School of Hygiene & Tropical Medicine, which is published in today's Occupation and Environmental Medicine journal.

1 Mar 2008

Vitamin supplements for lung cancer

Vitamin supplements do not protect against lung cancer, according to a study of more than 77,000 vitamin users.

1 Mar 2008

Protein protects lung cancer cells from efforts to fix or kill them

A protein that helps lung cancer cells thrive appears to do so by blocking healthy cells' ability to fix themselves when radiation or chemicals such as nicotine damage their DNA, according to a University of Florida study to be published Friday (Feb. 29) in the journal Molecular Cell.

28 Feb 2008

Glioblastoma multiforme responds to new treatment

One of the toughest cancers to treat effectively is glioblastoma multiforme (GBM), the most common form of primary brain cancer.

28 Feb 2008

Hydroxyurea for sickle cell patients

An independent panel convened this week by the NIH concluded that the use of hydroxyurea for sickle cell patients should be increased in adolescents and adults.

28 Feb 2008

India caught in the midst of catastrophic smoking epidemic

India is caught in the midst of a catastrophic smoking epidemic, which is causing one in five of all male deaths in middle age and will cause about one million deaths a year during the 2010s.

28 Feb 2008

New NIH cholesterol website for seniors

Many older adults have their blood cholesterol level checked regularly.

28 Feb 2008

Rresearch may lead to a better flu vaccine

New research from a scientist at the University of Tennessee, Knoxville, has uncovered information that may someday lead to a better flu vaccine.

28 Feb 2008

Discovery of potential drug targets for sepsis

"We have identified a key connection of signaling pathways in the cascade of events leading to sepsis. This defines a crucial point where the immune system spirals out of control to cause severe sepsis and where there is an opportunity for therapeutic intervention," says Scripps Research Professor Wolfram Ruf, who led the research with his postdoctoral fellow Frank Niessen.

28 Feb 2008

Inverted DNA turns quiet developmental gene into a potent driver of t-cell lymphoma

A gene crucial for embryonic development can quickly become a potent cancer promoter in adult mice after a genetic misalignment, according to researchers from Fox Chase Cancer Center, causing white blood cells to become cancerous spontaneously.

28 Feb 2008

Are cataract rates on the decline?

Should glaucoma patients seeking alternative therapies trust what they find online? Are seatbelts still important to protect eyes in auto accidents, now that most cars have airbags? What's the connection between hearing loss and one form of glaucoma? These are among the topics explored in the March 2008 issue of Ophthalmology, the journal of the American Academy of Ophthalmology.

28 Feb 2008

Drug for anemic cancer patients raises risk of death

Millions of cancer patients take drugs to boost their red blood cells and health when they become anemic after chemotherapy.

27 Feb 2008

Anemia drug linked to blood clots, death in cancer patients

Treating anemia with a class of drugs known as erythropoiesis-stimulating agents (ESAs) is associated with an increased risk of venous thromboembolism (blood clots in the deep veins of the legs or in the lungs) and death among patients with cancer, according to an article in the February 27 issue of JAMA: The Journal of the American Medical Association.

27 Feb 2008

Chronic diseases - good news and bad news for Australians

According to a new national report by the Australian Institute of Health and Welfare (AIHW), when it comes to chronic diseases there is good news and bad news.

26 Feb 2008

High zinc status in lung cells slows growth and induces DNA

Researchers at the University of Maryland at College Park have discovered that Normal Human Bronchial Epithelial (NHBE) cells cultured in medium with elevated zinc level, at the high end of plasma zinc attainable by oral supplementation, demonstrated inhibition of cell growth, up-regulation of growth arrest and DNA damage-induced gene (Gadd45) mRNA and protein expression, and blockage of G2/M cell cycle progression.

26 Feb 2008

Small protein discovered that specifically recognizes tumors responding to chemotherapy

A technique that specifically "tags" tumors responding to chemotherapy may offer a new strategy for determining a cancer treatment's effectiveness within days of starting treatment, according to a new study by Vanderbilt-Ingram Cancer Center investigators.

26 Feb 2008