Lupus Erythematosus News and Research

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Dietary components do not have impact on RMD outcomes

In 2022, EULAR - the European Alliance of Rheumatology Associations - published new recommendations regarding lifestyle behaviors and work participation to prevent progression of rheumatic and musculoskeletal diseases (RMDs).

1 Nov 2022

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Researchers gathered empirical evidence that past pandemics due to infectious pathogens shaped the present-day susceptibility of humans to diseases, such as autoimmune diseases.

24 Oct 2022

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

Researchers assess the role of neutrophil extracellular traps (NETs) in systemic autoimmune and autoinflammatory disorders.

23 Oct 2022

Scientists receive $8.297 NIH grant to continue funding a Center for Lupus Research

A multi-institutional team of scientists, led by researchers at Weill Cornell Medicine's Gale and Ira Drukier Institute for Children's Health, have received a five-year $8.297 grant to continue funding a Center for Lupus Research.

21 Oct 2022

Study reviews hydroxychloroquine and remdesivir antiviral potency against SARS‐CoV‐2

In a new study, researchers outlined the synthesis and the possible mechanism of action (MOA) of two potential severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) repurposing drug candidates.

17 Oct 2022

Researchers explore single-cell sequencing technologies to understand molecular mechanisms of autoimmune diseases

A new review discussed the applications of single-cell ribonucleic acid sequencing (scRNA-seq) in understanding autoimmune disorders.

17 Oct 2022

Could COVID-19 infections trigger a relapse of mycosis fungoides or other cutaneous T-cell lymphomas?

Recently, authors highlighted the potential role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in triggering the relapse of mycosis fungoides, a type of cutaneous T-cell lymphoma.

17 Oct 2022

Immune-mediated inflammatory diseases following COVID-19

Researchers explore the potential association between SARS-CoV-2 infection and immune-mediated inflammatory diseases.

12 Oct 2022

Review on COVID-19 biomedical waste-derived microplastic toxicity

In a new study, researchers reviewed existing literature on the biomedical waste source, elements, and the recent upsurge of microplastics during the SARS-CoV-2 pandemic.

11 Oct 2022

Study establishes a feasible combination therapeutic strategy for ulcerative colitis

Despite recent advancements in our knowledge of the pathogenic mechanisms of ulcerative colitis, there is still a considerable unmet medical need for the treatment of ulcerative colitis.

29 Sep 2022

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

In a new study, a team of researchers explored the effect of immune checkpoint blockade (ICB)-induced expansion of age-associated B cells (ABCs) on COVID-19 vaccine-derived humoral immunity in patients with cancer and inborn errors of immunity (IEI).

22 Sep 2022

Patients with autoimmune diseases at greater risk of complications after heart attack

In a recent study published in the Journal of the American Heart Association, researchers assessed midterm and management outcomes of acute myocardial infarction (AMI) among patients with rheumatic immune-mediated inflammatory diseases (IMIDs).

18 Sep 2022

New data analysis approach could help uncover the genetic basis of many diseases

In the era of Big Data, obtaining a huge amount of information is the easy part; knowing what to do with it is another story entirely.

9 Sep 2022

Clinical trial shows efficacy and safety of belimumab in East Asian adults with lupus nephritis

This prespecified subgroup analysis of East Asian adults who participated in a phase 3 clinical trial of belimumab added to standard therapy vs. placebo added to standard therapy for lupus nephritis shows earlier and more sustained improvement in kidney outcomes with the addition of belimumab.

2 Sep 2022

The origins, breadth, and resolution of autoreactivity in severe COVID-19

Researchers assessed naïve B cells and autoreactivity in severe COVID-19.

2 Sep 2022

People with autoimmune disorder have a higher risk of developing cardiovascular disease

Around ten percent of the population in high income regions like Europe and the United States has been diagnosed with one or multiple autoimmune disorders.

29 Aug 2022

Study reveals safety and uptake of sotrovimab against severe SARS-CoV-2 infection in England

In a newly released study, researchers explored the sotrovimab uptake for severe COVID-19 prophylaxis and its safety across the community populations in England.

22 Aug 2022

The QCOVID4 algorithm developed using data from the Omicron wave identifies those at highest risk of severe COVID-19 outcomes

A recent article illustrated the derivation and validation of the QCOVID4 risk determination algorithm for predicting COVID-19 hospitalization and death risk in England.

18 Aug 2022

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

A new study shows how mutation of the ADAR1 gene sets off biochemical pathways that produce an autoimmune response that harms the developing brain and other areas of the body.

2 Aug 2022

UT Southwestern physicians outline the risks of pregnancy in women with rheumatic disease

Pregnant women with active rheumatic disease carry a higher risk of adverse outcomes than the general population including hypertension, preeclampsia, higher cesarean section rate, small for gestational aged infants, preterm delivery, and fetal loss. To

19 Jul 2022

Lupus Erythematosus News and Research

Dietary components do not have impact on RMD outcomes

The Black Death may have influenced the evolution of genes involved in immune responses against pathogens

Overview of the roles of neutrophils in systemic autoimmune and autoinflammatory diseases

Scientists receive $8.297 NIH grant to continue funding a Center for Lupus Research

Study reviews hydroxychloroquine and remdesivir antiviral potency against SARS‐CoV‐2

Researchers explore single-cell sequencing technologies to understand molecular mechanisms of autoimmune diseases

Could COVID-19 infections trigger a relapse of mycosis fungoides or other cutaneous T-cell lymphomas?

Immune-mediated inflammatory diseases following COVID-19

Review on COVID-19 biomedical waste-derived microplastic toxicity

Study establishes a feasible combination therapeutic strategy for ulcerative colitis

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

Patients with autoimmune diseases at greater risk of complications after heart attack

New data analysis approach could help uncover the genetic basis of many diseases

Clinical trial shows efficacy and safety of belimumab in East Asian adults with lupus nephritis

The origins, breadth, and resolution of autoreactivity in severe COVID-19

People with autoimmune disorder have a higher risk of developing cardiovascular disease

Study reveals safety and uptake of sotrovimab against severe SARS-CoV-2 infection in England

The QCOVID4 algorithm developed using data from the Omicron wave identifies those at highest risk of severe COVID-19 outcomes

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

UT Southwestern physicians outline the risks of pregnancy in women with rheumatic disease

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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