Lymph Nodes News and Research

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New research hopes to uncover mystery behind breast cancer metastasis

If detected early, most cases of breast cancer are curable. But if the tumour has metastasized - or spread to a site outside of the breast - cure rates decline. A team of researchers from Lawson Health Research Institute and Western University have received $449,733 from the Canadian Breast Cancer Foundation - Ontario Region to study a rare subpopulation of tumour cells called cancer stem cells (CSCs) in hopes of uncovering the mystery behind metastasis.

8 Aug 2012

Myc-directed repression of tristetraprolin important for development and maintenance of cancer

Scientists from the Florida campus of The Scripps Research Institute have identified a protein that impairs the development and maintenance of lymphoma (cancer of the lymph nodes), but is repressed during the initial stages of the disease, allowing for rapid tumor growth.

3 Aug 2012

Treatment with robotic surgery offers dramatic benefit for people with head and neck cancer

Predictors of disease severity in human papillomavirus-derived head and neck cancer, tobacco use, and the dramatic benefits of robotic surgery in people with head and neck cancer are among landmark research presented by Mount Sinai School of Medicine at the Eighth International Conference on Head and Neck Cancer. The meeting took place from July 21-25, 2012 in Toronto.

27 Jul 2012

Navidea announces results from Lymphoseek Phase 3 trial on head and neck squamous cell carcinoma

Navidea Biopharmaceuticals, Inc., a biopharmaceutical company focused on precision diagnostic radiopharmaceuticals, noted today that individual site, investigator-initiated results of an ongoing Phase 3 clinical trial of 99m-Tc-Tilmanocept (Lymphoseek) were presented at the American Head and Neck Society's 8th International Conference on Head and Neck Cancer (ICHNC), held in Toronto, July 21-25, 2012.

27 Jul 2012

Insight into possible new approaches in vaccine development for blood-borne infections and HIV

White blood cells called neutrophils, which are the first line of defense against infection, play an unexpected role by boosting antibody production, according to research led by Mount Sinai School of Medicine. The findings suggest neutrophils have multiple roles within the immune system and function at levels previously unknown to the scientific community. The research, published in Nature Immunology, provides groundbreaking insight into possible new approaches in vaccine development for blood-borne infections and HIV.

25 Jul 2012

US hospitals fail to meet critical esophagectomy benchmark

A study has shown that most US hospitals fail to ensure that surgeons examine at least 15 lymph nodes during esophagectomy for cancer, and are therefore failing to meet guideline recommendations for detecting metastases.

12 Jul 2012

HIV and AIDS treatment: An interview with Charles Flexner, MD

The best estimates at the moment reckon that there are about 25 million people infected with HIV. Most of those are in resource-limited settings, including sub-Saharan Africa, South East Asia and India.

11 Jul 2012

PENTAX Medical introduces EG-3270UK endoscope

PENTAX Medical sets a new standard in endoscopic ultrasound with the official launch of the EG-3270UK endoscope during the 30th GEEW congress in Brussels, Belgium.

From PENTAX Medical Company 10 Jul 2012

Blocking AXL protein may prevent resistance to lung cancer drug

People with lung cancer who are treated with the drug Tarceva face a daunting uncertainty: although their tumors may initially shrink, it's not a question of whether their cancer will return—it's a question of when. And for far too many, it happens far too soon.

2 Jul 2012

Researchers probe origin of optimized antibodies against infections

An organism's ability to make new antibodies and use them to optimize its own immune defenses is of central importance in the fight against pathogens. In the case of severe infections, the overall relative speed with which an immune response proceeds could mean the difference between life and death.

29 Jun 2012

Pediatric Hodgkin lymphoma can be treated without radiation and intensive chemotherapy

A multicenter trial showed that nearly half of young patients with early-stage Hodgkin lymphoma can be cured without undergoing either irradiation or intensive chemotherapy that would leave them at risk for second cancers, infertility, heart and other problems later.

28 Jun 2012

First study to demonstrate that microbes are specific to their host species

Gut bacteria's key role in immunity is tuned to the host species, researchers have found, suggesting that the superabundant microbes lining our digestive tract evolved with us-a tantalizing clue in the mysterious recent spike in human autoimmune disorders.

23 Jun 2012

Even small-stage oral SCC metastases impact prognosis

The presence of even small tumor-cell deposits in the lymph nodes of patients with early oral and oropharyngeal squamous cell carcinoma reflects a potential for the primary tumor to metastasize, report researchers in Head and Neck.

21 Jun 2012

Scientists discover master regulator gene needed for development of M cells

Scientists have found a master regulator gene needed for the development of M cells, a mysterious type of intestinal cell involved in initiating immune responses.

18 Jun 2012

Variations in microRNA expression within breast tumors can lead to sampling bias

Certain short strands of RNA, known as microRNAs (miRNAs), have been linked to the progression and metastasis of breast cancer and may provide information about prognosis. However, studies of miRNA expression profiles often report conflicting findings. While the potential for using miRNAs in breast cancer diagnosis is promising, scientists report in a new study published online today in The Journal of Molecular Diagnostics that differences in the amount and types of miRNA within breast tumors can be misleading.

15 Jun 2012