Lymph Nodes News and Research

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Profile of immune cells in axillary lymph nodes predicts disease-free survival in breast cancer

Breast cancer often spreads through the lymph nodes in the arm pits (so-called axillary lymph nodes), and whether these lymph nodes are tumor-free or contain small metastases is an important factor in the decision of how aggressively to treat a patient.

6 Sep 2005

New way to assess risk of breast cancer recurrence

Currently, the best way to predict whether a breast cancer is likely to recur is to determine whether tumor cells have invaded the lymph nodes near the breast.

5 Sep 2005

Researchers discover one of the reasons why melanoma is so ruthless

About 60,000 Americans will be diagnosed with melanoma this year, says the American Cancer Society, and 10,000 of those cases will be fatal. If not caught in the early stages, melanoma can be a particularly virulent form of cancer, spreading through the body with an efficiency that few tumors possess.

5 Sep 2005

Compound might defeat African sleeping

One of the most devastating diseases in sub-Saharan Africa almost disappeared in the late 1950s.

26 Aug 2005

A preoperative testing strategy may help determine stage of lung cancer more accurately

A preoperative testing strategy combining two procedures may help improve the accuracy of determining the stage of lung cancer, according to an article in the August 24/31 issue of JAMA: The Journal of the American Medical Association.

23 Aug 2005

Sentinel node biopsy, when performed before chemotherapy to shrink the tumor, is very reliable

New breast cancer research shows for the first time that even women with large breast tumors can benefit from a less invasive biopsy method that has been reserved until now for women with small breast cancers.

23 Aug 2005

Protein thought to promote lymphoma by merely preventing cancer cells from dying appears to actively promote cancer cell growth

A protein previously thought to merely hinder the activity of a key cellular protein linked to cancer cell death, now appears to mimic the cellular signaling of that protein; potentially leading to the development of lymphoma.

22 Aug 2005

Experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma

Researchers at The University of Texas M. D. Anderson Cancer Center and the National Cancer Institute have found that an experimental vaccine can prime the immune system to help fight an aggressive form of lymphoma, even though prior therapy had eliminated virtually all of the B cells thought necessary to mount such a defense.

22 Aug 2005

Women whose breast cancer is detected by mammography have a significantly better prognosis

Women whose breast cancer was detected by screening mammography had a significantly better prognosis than those whose cancer was found another way - even if the cancer had already spread to their lymph nodes, say researchers at The University of Texas M. D. Anderson Cancer Center who looked at outcomes from randomized screening studies of more than 150,000 women.

17 Aug 2005

Positron emission tomography (PET) imaging can identify effectiveness of chemotherapy early in high-risk breast cancer patients

The effectiveness of chemotherapy in patients with advanced breast cancer can be evaluated earlier by using 18F-FDG positron emission tomography (PET) imaging over other conventional imaging procedures, according to an article in the July issue of the Society of Nuclear Medicine's Journal of Nuclear Medicine.

26 Jul 2005

Scientists have begun to clarify how one of the body's molecules controls the trafficking of T cells through the blood

...lymph nodes and on to tissues to fight infection -- a crucial response that sometimes goes awry, attacking the body's own tissues and causing autoimmune diseases.

17 Jul 2005

Doctor blames parents for return of sick girl's cancer

Thirteen year old Katie Wernecke is back in hospital after doctors confirmed the girls Hodgkin's disease had returned.

16 Jun 2005

FDA approves Xeloda (capecitabine) oral chemotherapy

Roche announced today that the U.S. Food and Drug Administration (FDA) has approved Xeloda (capecitabine) -- an innovative oral chemotherapy -- for the adjuvant (post-surgery) treatment of patients with Dukes' C colon cancer.

15 Jun 2005

Many breast cancer patients experience longterm arm and hand swelling after treatment

More than 55 percent of 580 breast cancer patients in a study, experienced swelling in the arms or hands , a condition known as lymphedema, after surgical removal of either the breast or the tumor.

13 Jun 2005

Half of 580 women diagnosed with breast cancer in one study experienced lymphedema

The good news is that there are nearly two million breast cancer survivors in the United States , and survival rates continue to increase for patients with this disease. But the flip side is that survival can present its own set of little-known complications.

12 Jun 2005

Dendritic cell vaccination can dramatically speed up the immunization process

Parents often wonder why it takes a year or more and multiple shots to fully immunize their children against diseases like diphtheria and pertussis.

12 Jun 2005

Study clarifies risk of recurrence for high-risk breast cancer patients

High-risk breast cancer patients do not appear to have a higher risk of relapse than the general breast cancer population during the first two years after diagnosis, unless their cancer has spread to more than 10 axillary lymph nodes, Italian researchers reported at the 2nd ESMO Scientific & Educational Conference (ESEC) in Budapest, Hungary.

6 Jun 2005

Newly discovered gene could provide targets for diabetes therapies

The Juvenile Diabetes Research Foundation (JDRF) has announced that JDRF-funded researchers in Australia and the United Kingdom have identified a gene called Roquin that regulates the immune system and keeps harmful T cells in check.

1 Jun 2005

Concurrent radiation, chemo, followed by surgery lengthens lung cancer patients' survival

Patients whose lung cancer has spread to the lymph nodes have a better chance of long-term survival if they receive combined modality therapy, such as concurrent radiation and chemotherapy followed by surgery, according to a study that Loyola University Health System’s Dr. Kathy S. Albain presented at the American Society of Clinical Oncology annual meeting.

18 May 2005

Breast cancer chemotherapy regimen associated with life-threatening complications

The chemotherapy regimen of doxorubicin plus docetaxel, used to treat breast cancer in a clinical trial, was associated with an increased risk of serious complications, resulting in the premature termination of the trial, according to a study in the May 18 issue of JAMA.

17 May 2005