Macromolecules News and Research

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Researchers characterize the proteome of the human cornea

In doing so, they have identified 141 distinct proteins, 99 of which had not been previously recognized in mammalian corneas. The details of their findings appear in the August/September issue of Molecular and Cellular Proteomics, an American Society for Biochemistry and Molecular Biology journal.

1 Aug 2005

A new method for manipulating macromolecules

The technique uses double-stranded DNA to direct the behavior of other molecules. In previous DNA nanotechnology efforts, duplex DNA has been used as a static lattice to construct geometrical objects in three dimensions.

29 Jun 2005

Nanoscale mechanism to externally control the function and action of a protein

"We can switch a protein on and off, and while we have controlled a specific protein, we believe our approach will work with virtually any protein," said Giovanni Zocchi, assistant professor of physics at UCLA, member of the California NanoSystems Institute and leader of the research effort. "This research has the potential to start a new approach to protein engineering."

16 Feb 2005

Wide angle X-ray scattering (WAXS) could help produce lead drugs for disease therapy

Structural changes in proteins can now be seen in increased detail, using a new application of an existing technique. The application, developed at the U.S. Department of Energy's Argonne National Laboratory, could help produce lead drugs for disease therapy.

8 Dec 2004

Transparent gel could soon become the first and best choice for sealing corneal incisions

The substance, known as a hydrogel, promises to be a useful tool in the kit used for the most common of ophthalmic surgeries: cataract removal. Currently, 11 million such surgeries are performed worldwide annually, a figure expected to increase as the world's population grows older.

12 Oct 2004

New glycan arrays discover autoimmunogenic activities of SARS-CoV

Researchers in New York City and Guangzhou, China applied the rapidly-developing carbohydrate microarray technology to study an inactivated SARS-coronavirus (SARS-CoV) vaccine and discovered autoimmunogenic activity of this newly identified human viral pathogen.

2 Aug 2004

Online database of AIDS-related protein structures

Researchers who are either developing drug treatments for AIDS or studying the virus that causes the disease have a new resource - an online database of AIDS-related protein structures just unveiled for public use by the National Institute of Standards and Technology.

16 Jul 2004

SkyePharma delivery technologies for respiratory drugs to feature at two international conferences

SkyePharma PLC has announced that its proprietary delivery technologies for respiratory drugs will be presented later this month at two international conferences, one in the UK and one in America.

22 Apr 2004