Malignant News and Research

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High-grade gliomas remodel neural circuits: promoting tumor progression and impaired cognition

Researchers investigated whether functional connectivity between glioblastoma and the brain affected neural circuits.

9 May 2023

Organoids derived from cancer cells can reduce the need for trial and error in identifying effective treatments

Researchers created organoids from cancer cells to reduce the need for trial and error in identifying effective cancer treatments in one of many cancer studies scheduled for presentation this week at Digestive Disease Week (DDW) 2023.

8 May 2023

Combination treatment shows promise for aggressive subtype of non-Hodgkin lymphoma

Nearly 90 percent of patients with an aggressive subtype of non-Hodgkin lymphoma had their cancer go into remission in a small phase 2 clinical trial testing a treatment aimed at making chemotherapy more effective, according to Weill Cornell Medicine and NewYork-Presbyterian investigators.

5 May 2023

Study evaluates simultaneous effects of exercise and diet-induced weight reduction in patients with type 2 diabetes

Researchers performed a four-armed, 16-week randomized clinical trial on type II diabetes.

3 May 2023

Using PandaOmics to identify dual-purpose therapeutic targets to treat aging and glioblastoma

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 8, entitled, "Identification of dual-purpose therapeutic targets implicated in aging and glioblastoma multiforme using PandaOmics - an AI-enabled biological target discovery platform."

3 May 2023

AI can analyze breast mass images to accurately identify cancer in low-resource settings

Artificial intelligence (AI) can analyze breast mass images from low-cost portable ultrasound machines and accurately identify cancer, according to a study published in Radiology, a journal of the Radiological Society of North America.

2 May 2023

3D genome mapping may lead to the treatment of deadliest pediatric brain tumors

Researchers led by Sanford Burnham Prebys assistant professor Lukas Chavez, Ph.D., are leveraging the latest technology to take a never-before-seen look at ependymoma, one of the deadliest pediatric brain tumors.

27 Apr 2023

Research develops unique delivery system to treat osteosarcoma

New research has identified a potential therapeutic target and developed a unique delivery system to treat osteosarcoma, a bone cancer that primarily affects children and adolescents.

27 Apr 2023

Study evaluates the effects of phenolic compounds in extra virgin olive oil on skin health

Researchers evaluated the effects of phenolic compounds in extra virgin olive oil on human fibroblasts.

27 Apr 2023

New class of immunotherapy shows promise against aggressive skin cancer

A new class of immunotherapy shows promising results for fighting the most aggressive form of skin cancer.

25 Apr 2023

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

24 Apr 2023

Research findings could help inform more effective therapies for AML

Acute myeloid leukemia (AML) is a type of cancer in which the bone marrow makes a large number of abnormal blood cells. It is the most common type of acute leukemia in adults.

24 Apr 2023

A downstream pathway critical for lymphoma development discovered

MYC proteins are important regulators of cancer cell growth, proliferation and metabolism through their ability to increase the expression of proteins involved in these processes.

20 Apr 2023

Study shows effectiveness, safety of stereotactic radiosurgery for NF2-related vestibular schwannomas

Vestibular schwannomas related to neurofibromatosis type 2 (NF2) are difficult to manage and are sometimes treated with a noninvasive option, stereotactic radiosurgery.

18 Apr 2023

Uncovering the connection between the microbiome and aging

Researchers evaluated the recent advances in understanding how the microbiome influences aging and associated diseases.

15 Apr 2023

Curtin researchers identify the genetic signature of pre-malignant liver cells

Researchers at Curtin University have identified the genetic signature of pre-malignant liver cells, offering potentially significant implications for the almost 3,000 Australians diagnosed with the deadly cancer each year.

13 Apr 2023

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain cancer that often kills within a year of diagnosis. Surgery is almost impossible because of the tumors' location.

12 Apr 2023

For uninsured people with cancer, securing care can be like spinning a roulette wheel

Eighteen months after April Adcox learned she had skin cancer, she finally returned to Charleston's Medical University of South Carolina last May to seek treatment.

10 Apr 2023

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Understanding how cancer develops is critical for designing effective, personalized cancer therapies. Researchers have known for years that cancer begins with mutations in certain types of genes.

6 Apr 2023

People with a rare form of brain and spinal cord cancer have poor prognosis, research reports

A team of researchers from the Nagoya University Graduate School of Medicine has reported that patients with a rare form of brain and spinal cord cancer, localized isocitrate dehydrogenase wild-type (IDHwt) histologically diffuse astrocytoma, have a poor prognosis similar to the most malignant types of brain and spinal cord tumors.

31 Mar 2023

Malignant News and Research

High-grade gliomas remodel neural circuits: promoting tumor progression and impaired cognition

Organoids derived from cancer cells can reduce the need for trial and error in identifying effective treatments

Combination treatment shows promise for aggressive subtype of non-Hodgkin lymphoma

Study evaluates simultaneous effects of exercise and diet-induced weight reduction in patients with type 2 diabetes

Using PandaOmics to identify dual-purpose therapeutic targets to treat aging and glioblastoma

AI can analyze breast mass images to accurately identify cancer in low-resource settings

3D genome mapping may lead to the treatment of deadliest pediatric brain tumors

Research develops unique delivery system to treat osteosarcoma

Study evaluates the effects of phenolic compounds in extra virgin olive oil on skin health

New class of immunotherapy shows promise against aggressive skin cancer

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

Research findings could help inform more effective therapies for AML

A downstream pathway critical for lymphoma development discovered

Study shows effectiveness, safety of stereotactic radiosurgery for NF2-related vestibular schwannomas

Uncovering the connection between the microbiome and aging

Curtin researchers identify the genetic signature of pre-malignant liver cells

New potential therapeutic developed for diffuse intrinsic pontine glioma using ASO technology

For uninsured people with cancer, securing care can be like spinning a roulette wheel

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

People with a rare form of brain and spinal cord cancer have poor prognosis, research reports

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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