Malignant News and Research

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New target for cancer therapy identified by Australian researchers

A new target for cancer therapy has been identified by Monash University scientists investigating the cell signalling pathways that turn on a gene involved in cancer development.

21 Sep 2006

Earlier detection and treatment of kidney cancer not decreasing mortality

The number of cases of kidney cancer has been rising over the last two decades, and new research from the University of Michigan Comprehensive Cancer Center shows that this increase is driven largely by the detection of small, presumably curable, kidney masses.

19 Sep 2006

Cell detachment model for an antibody-based microfluidic cancer screening system

In the quest to detect more types of cancers at ever earlier stages, researchers have been stymied by a lack of cell surface markers that distinguish in a clear-cut manner between healthy and malignant cells.

19 Sep 2006

Cisplatin nanoliposomes for cancer therapy

Cisplatin is one of the most powerful and effective drugs for treating a wide variety of cancers, but many tumors develop resistance to this drug, ultimately limiting its benefits for cancer patients.

19 Sep 2006

Quality indicators for gastrointestinal endoscopic procedures

Defining measurements and identifying quality standards in the delivery of colonoscopic care is a major priority for the nation's leading gastrointestinal endoscopic healthcare association.

13 Sep 2006

NIH to map genomic changes of lung, brain, and ovarian cancers

It is estimated that 174,470 new cases of lung cancer will be diagnosed in the United States in 2006. Lung cancer is the major cause of cancer-related mortality in both men and women, with an estimated 162,460 deaths expected to occur in 2006.

13 Sep 2006

Synthetic low-density lipoprotein-like nanoparticles target brain tumors

Low-density lipoprotein, better known as LDL, is one of the chief villains involved in the development of coronary artery disease.

12 Sep 2006

Reactive oxygen species in cancer cells

A biochemical alteration that has long been viewed as an adverse aspect of tumor biology may turn out to be a deadly double-edged sword for the cancer cells themselves.

12 Sep 2006

UIC receives $20 million NCI grant to research blood disorders

A $19.6 million National Cancer Institute grant has been awarded to the University of Illinois at Chicago College of Medicine to advance basic and clinical research for incurable blood disorders.

6 Sep 2006

Targeted nanoparticles to improve Boron-Neutron capture therapy

Boron-neutron capture therapy (BNCT) is an experimental treatment for virulent brain cancer that aims to kill malignant cells by generating high-energy alpha particles inside tumors.

5 Sep 2006

Induction of potent antitumor immunity by intratumoral injection of IL-23 transduced dendritic cells

One therapy for treating brain tumors alerts the immune system to the presence of foreign material. A second therapy enhances the first and prolongs the immune system's response.

4 Sep 2006

Mature muscle fibers can revert to become cancerous

Mature muscle fibers, rather than their less-developed neighbors, are the tissues that turn malignant in a soft-tissue cancer that strikes children and teens, researchers at UT Southwestern Medical Center and Children's Medical Center Dallas have found.

4 Sep 2006

Celebrex shown to reduce incidence of potentially pre-malignant colorectal polyps

An international team of scientists reports that a single 400-milligram daily dose of celecoxib, commonly called Celebrex. and manufactured by Pfizer, significantly reduced recurrence of adenomas, or pre-malignant colon tumors - within three years of previous adenoma removal.

30 Aug 2006