Malignant News and Research

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Veggies reduce the risk of developing lung cancer in smokers

Eating vegetables and other foods that have weak estrogen-like activity appears to reduce the risk of developing lung cancer in smokers - as well as in non-smokers, say researchers at The University of Texas M. D. Anderson Cancer Center.

27 Sep 2005

Combining optical tomography with standard ultrasound imaging can help distinguish early-stage breast cancer

A new study shows that combining a technology called optical tomography with standard ultrasound imaging can help distinguish early-stage breast cancer from non-cancerous lesions--and potentially reduce the number of breast biopsies performed. The study appears in the October issue of the journal Radiology.

27 Sep 2005

Work absence after breast cancer diagnosis

Breast cancer is a very common malignancy with serious health effects that often involves women in the prime of their lives. Drolet and colleagues report on the work experience of women recently diagnosed with breast cancer.

27 Sep 2005

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

...a discovery that could pave the way for more effective cancer treatments.

27 Sep 2005

A new, less toxic way to treat malignant melanoma

A new, less toxic way to treat malignant melanoma (skin cancer) is being developed by medicinal chemists at Reading University. They have produced a range of prodrugs: compounds that offer the potential to be converted to toxic molecules only within the vicinity of tumours. These prodrugs aim to reduce the toxicity of treatment.

26 Sep 2005

Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells

The finding represents a step forward in understanding the molecular events that govern the growth of this type of cancer and the changes in gene expression and cellular signaling that underlie resistance to established therapies.

26 Sep 2005

Link between tissue tension and tumor formation

Most investigations into cancer have focused on chemical signals, but a new research study provides rare insight into how mechanical force can regulate cellular behavior.

20 Sep 2005

Injury prevention could save Maryland at least $700 million per year

In 2003, the total estimated cost of injuries in Maryland due to lost productivity and premature mortality was $1.9 billion dollars.

19 Sep 2005

Study points to importance of MYC gene in cancer progression

The cancer gene MYC is among the most commonly overexpressed oncogenes in human cancers. Most human cancers demonstrate high levels of MYC or its biological partners, including those of the breast, ovaries, lung, prostate, and skin, as well as leukemias and lymphomas.

19 Sep 2005

Compounds found in broccoli, cauliflower, and watercress block lung cancer progression

A family of compounds found in cruciferous vegetables, such as broccoli, cauliflower, and watercress, blocked lung cancer progression in both animal studies and in tests with human lung cancer cells, report researchers from Georgetown University Medical Center and the Institute for Cancer Prevention.

19 Sep 2005

New and unusual class of genes plays an important role in the development of chronic lymphocytic leukemia

The study found that the loss of two genes for producing small molecules known as microRNAs enables damaged cells to survive, rather than normally self-destructing before they become cancerous.

12 Sep 2005

Combining radiation, chemotherapy and liver transplantation increases survival in bile duct cancer patients

A new treatment for patients with a type of bile duct cancer promises a greater chance at survival by combining radiation, chemotherapy and liver transplantation, Mayo Clinic physicians report in the September issue of the Annals of Surgery.

12 Sep 2005

Translation elongation factor eEF1A2 is is a potential oncogene that is overexpressed in two-thirds of breast tumors

The tissue-specific elongation factor eEF1A2 might be an oncoprotein involved in breast cancer.

12 Sep 2005

Researchers discover one of the reasons why melanoma is so ruthless

About 60,000 Americans will be diagnosed with melanoma this year, says the American Cancer Society, and 10,000 of those cases will be fatal. If not caught in the early stages, melanoma can be a particularly virulent form of cancer, spreading through the body with an efficiency that few tumors possess.

5 Sep 2005

Rev/Dex combo looks like a breakthrough treatment for multiple myeloma

Mayo Clinic Cancer Center investigators report that combination therapy with lenalidomide (Revlimid) and dexamethasone (combination is called Rev/Dex) looks like a breakthrough treatment for multiple myeloma. Results of a Phase II clinical trial were published online Aug. 23 in Blood.

1 Sep 2005

Toluidine blue dye reveals oral cancers

A team of Canadian scientists may have discovered a way to use a simple dye as a litmus test to identify abnormal areas of the mouth that may become cancers.

1 Sep 2005

Study shows potential treatment for brain cancer

A compound that kills cancer can sneak past the blood brain barrier, which protects the brain from foreign substances, to do its work in fighting a particularly invasive brain cancer, according to a new Saint Louis University animal study published in the Proceedings of the National Academy of Sciences Online Early Edition the week of Aug. 22.

22 Aug 2005

Protein thought to promote lymphoma by merely preventing cancer cells from dying appears to actively promote cancer cell growth

A protein previously thought to merely hinder the activity of a key cellular protein linked to cancer cell death, now appears to mimic the cellular signaling of that protein; potentially leading to the development of lymphoma.

22 Aug 2005

Adult stem cells may play a role in the development of some forms of cancer

Researchers at UT Southwestern Medical Center have determined that stem cells in a certain region of the brain may be the source of a particular type of incurable brain tumor and may be implicated in other types of brain cancers as well.

16 Aug 2005

FDA approval sought for Pfizer's new cancer drug

Drug company Pfizer has announced it has submitted a New Drug Application (NDA) for its cancer drug Sutent, to the U.S. Food and Drug Administration (FDA).

11 Aug 2005

Malignant News and Research

Veggies reduce the risk of developing lung cancer in smokers

Combining optical tomography with standard ultrasound imaging can help distinguish early-stage breast cancer

Work absence after breast cancer diagnosis

Researchers at Johns Hopkins have identified three new genetic mutations in brain tumors

A new, less toxic way to treat malignant melanoma

Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells

Link between tissue tension and tumor formation

Injury prevention could save Maryland at least $700 million per year

Study points to importance of MYC gene in cancer progression

Compounds found in broccoli, cauliflower, and watercress block lung cancer progression

New and unusual class of genes plays an important role in the development of chronic lymphocytic leukemia

Combining radiation, chemotherapy and liver transplantation increases survival in bile duct cancer patients

Translation elongation factor eEF1A2 is is a potential oncogene that is overexpressed in two-thirds of breast tumors

Researchers discover one of the reasons why melanoma is so ruthless

Rev/Dex combo looks like a breakthrough treatment for multiple myeloma

Toluidine blue dye reveals oral cancers

Study shows potential treatment for brain cancer

Protein thought to promote lymphoma by merely preventing cancer cells from dying appears to actively promote cancer cell growth

Adult stem cells may play a role in the development of some forms of cancer

FDA approval sought for Pfizer's new cancer drug

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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