Malignant News and Research

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Researchers to test new leukemia drug

Chronic myeloid leukemia (CML) is a malignant cancer of the blood that affects people of all ages. While treatment is available for most of these patients, approximately 20 percent of them do not respond to it. Researchers at McGill teaching hospitals will soon study the effects of a new alternative therapy.

12 Jan 2005

Velcade (bortezomib) phase III clinical trial initiated in patients with newly diagnosed multiple myeloma

Millennium Pharmaceuticals today announced, in collaboration with Johnson & Johnson Pharmaceutical Research & Development, LLC, the initiation of VISTA (Velcadeas Initial Standard Therapy in multiple myeloma: Assessment with melphalan and prednisone), a multicenter, international phase III clinical trial of Velcadein combination with melphalan and prednisone versus melphalan and prednisone in patients with newly diagnosed multiple myeloma (MM) who are not transplant candidates.

10 Jan 2005

Why the Mediterranean diet appers to protect against breast cancer

U.S. researchers have uncovered reasons why the Mediterranean diet, with its high intake of oleic acid-rich olive oil, seems to protect against breast cancer. They have also found evidence that oleic acid may have a future role in treatment. The findings are reported (Monday 10 January) in Annals of Oncology.

9 Jan 2005

Novel Structure Proteins (NSP) could help predict the possibility of tumor growth in a patient

A new family of genes called Novel Structure Proteins (NSP) discovered by researchers in the Sbarro Institute for Cancer Research and Molecular Medicine in Temple University’s College of Science and Technology could have the potential for predicting the possibility of tumor growth in a patient.

9 Jan 2005

Core promoter mutants of Hepatitis B Virus e Antigen associated with development of fulminant hepatitis and liver cancer

Scientists in Brown Medical School, Providence, USA, have found that core promoter mutants of Hepatitis B Virus e Antigen replicate at up to 10-fold higher levels in transfected human hepatoma cells than the wild-type virus.

9 Jan 2005

Potential cure for lymphoma in HIV patients

Stem cell transplants have become the standard of care for patients with relapsed lymphoma, but not for patients who suffer from both this disease and HIV.

7 Jan 2005

Technique that could begin to make the staging of cancer both more accurate and less invasive

In a paper published in the premier open-access medical journal PloS Medicine this month, Mukesh Harisinghani and Ralph Weissleder describe a technique that could begin to make the staging of cancer both more accurate and less invasive.

28 Dec 2004

Why hair turns grey

Few things about growing older are as inevitable and obvious as "going gray," yet scientists have been unable to explain the precise cause of this usually unwelcome transformation.

23 Dec 2004

The burgeoning Indian AIDS epidemic

India, home to one-sixth of the human race, has an AIDS epidemic. Five million Indians are living with HIV infection. The stakes are high; the government is racing against time.

21 Dec 2004

Blocking gene's activity may control deadly skin cancer without harming normal cells

Researchers at Dana-Farber Cancer Institute and Children's Hospital Boston have discovered that malignant melanoma, the potentially lethal skin cancer, can't grow without a steady supply of a protein that normal cells can do without.

20 Dec 2004

Vaccine against cervical cancer

Dutch researcher Laura Bungener has developed a vaccine against cervical cancer. Vaccinated laboratory animals no longer developed the disease and animals which had already developed a tumour, could be treated with the vaccine.

20 Dec 2004

Combined positron emission tomography and computerized tomography can help diagnose hidden recurrent cancer

Combined positron emission tomography and computerized tomography (PET/CT) can help diagnose occult (hidden) recurrent cancer, possibly a cancer patient's greatest post-treatment fear, report a team of Israeli physicians in the December issue of the Society of Nuclear Medicine's "Journal of Nuclear Medicine."

13 Dec 2004

Revival of a unique and proven cancer treatment, neutron therapy

Northern Illinois University has announced plans to revive a unique and proven cancer treatment that blends advanced medical science with accelerator physics developed at Fermi National Accelerator Laboratory, a Department of Energy laboratory in Batavia, Ill.

7 Dec 2004

Revlimid clinical data in newly diagnosed multiple myeloma presented

Celgene Corporation announced today that data evaluating clinical results on Revlimid (lenalidomide) as a new therapeutic approach for patients with newly diagnosed multiple myeloma (MM) was presented at the American Society of Hematology 46th Annual Meeting in San Diego.

7 Dec 2004

Novel mutagenesis screen used to identify genetic suppressors of thrombosis

Researchers using a novel sensitized ENU (N-ethyl-N-nitrosourea, a carcinogen-induced animal tumor model established to grow malignant and benign tumors) mutagenesis (induction of mutation) screen in laboratory mice have developed a promising approach to genetic screening that can increase the likelihood of identifying dominant suppressors of thrombosis.

6 Dec 2004

Zevalin highly effective in first-line treatment of low-grade follicular lymphoma

Results from a clinical trial presented at the American Society of Hematology 46th Annual Meeting and Exposition (ASH) demonstrated that Zevalin (ibritumomab tiuxetan), administered as a first-line therapy, induced a 100 percent response rate in a small population of patients with low-grate follicular lymphoma (FL).

6 Dec 2004

Researchers step closer to cure for common childhood cancer

Acute lymphoblastic leukemia (ALL) is a malignant disease caused by the abnormal growth and development of white blood cells (WBC) in the bone marrow and blood. ALL is the most common cancer occurring in children with an annual rate of approximately 30 to 40 new cases per million.

5 Dec 2004

Herpes virus offers new hope in search for cure for cancer

In laboratory studies at Cincinnati Children's Hospital Medical Center, researchers have successfully treated the most common malignant abdominal tumor of childhood: neuroblastoma tumors.

4 Dec 2004

Fossil record of the human immune system reveals antibodies that block cancer metastasis

A team of researchers at The Scripps Research Institute has reconstructed the "fossil record" of the immune systems of a group of human cancer patients to investigate if they had ever produced antibodies against their disease.

4 Dec 2004

New non-surgical technique that can help doctors determine when breast cancer has invaded the lymph nodes

A key question after a cancer diagnosis is whether the cancer has spread to nearby lymph nodes. Researchers at the University of Michigan Comprehensive Cancer Center have found a new non-surgical technique that can help doctors determine when breast cancer has invaded the lymph nodes, sparing some women an extra trip to the operating room.

29 Nov 2004

Malignant News and Research

Researchers to test new leukemia drug

Velcade (bortezomib) phase III clinical trial initiated in patients with newly diagnosed multiple myeloma

Why the Mediterranean diet appers to protect against breast cancer

Novel Structure Proteins (NSP) could help predict the possibility of tumor growth in a patient

Core promoter mutants of Hepatitis B Virus e Antigen associated with development of fulminant hepatitis and liver cancer

Potential cure for lymphoma in HIV patients

Technique that could begin to make the staging of cancer both more accurate and less invasive

Why hair turns grey

The burgeoning Indian AIDS epidemic

Blocking gene's activity may control deadly skin cancer without harming normal cells

Vaccine against cervical cancer

Combined positron emission tomography and computerized tomography can help diagnose hidden recurrent cancer

Revival of a unique and proven cancer treatment, neutron therapy

Revlimid clinical data in newly diagnosed multiple myeloma presented

Novel mutagenesis screen used to identify genetic suppressors of thrombosis

Zevalin highly effective in first-line treatment of low-grade follicular lymphoma

Researchers step closer to cure for common childhood cancer

Herpes virus offers new hope in search for cure for cancer

Fossil record of the human immune system reveals antibodies that block cancer metastasis

New non-surgical technique that can help doctors determine when breast cancer has invaded the lymph nodes

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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