Malignant News and Research

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New computer-aided diagnosis (CAD) methods for cancer

Not all masses are cancer. When a person undergoes a scan to identify a lump or nodule, the radiologist looks at the texture, the borders and the shape to determine if it is malignant or just a benign growth.

29 Nov 2004

New genetic test has proven useful as a prognostic tool for ovarian cancer

The identification of a gene expression profile using microarray technology may help clinicians better determine the prognosis of patients with advanced stage ovarian cancer and may eventually help provide targeted therapies for this hard-to-treat disease, according to a study led by investigators at Beth Israel Deaconess Medical Center (BIDMC).

18 Nov 2004

Understanding the signals that delay the spread of follicular lymphoma could provide new therapeutic targets

Scientists at the National Cancer Institute (NCI), have created a model that predicts the survival of follicular lymphoma patients based on the molecular characteristics of their tumors at diagnosis.

18 Nov 2004

Troponin genes offer new insights to familial heart failure

Mutations in the troponin protein complex may be useful for predicting the course of heart failure due to dilated cardiomyopathy and also for guiding treatment and research, according to a new study in the Nov. 16, 2004 issue of the Journal of the American College of Cardiology.

16 Nov 2004

Lorus Therapeutics allowed Canadian patent to protect anticancer drugs

Lorus Therapeutics today announced that its wholly owned subsidiary, GeneSense Technologies Inc., has been allowed a patent by the Canadian Patent Office entitled "Antitumor Antisense Sequences Directed Against R1 and R2 Components of Ribonucleotide Reductase."

10 Nov 2004

MRI technique for measuring blood volume helps distinguish between abscesses and tumors in the brain

Dynamic susceptibility contrast (DSC) MRI allows physicians to differentiate between cerebral abscesses—inflamed areas in the brain caused by infection—and malignant brain tumors without surgery, says a new preliminary study by researchers from Duke University Medical Center in Durham, NC.

8 Nov 2004

FDA fast tracks investigational anti-cancer drug, phenoxodiol

Marshall Edwards today announced that the U.S. Food and Drug Administration (FDA) has granted the investigational anti-cancer drug, phenoxodiol, Fast Track status for its intended use in patients with recurrent ovarian cancer.

4 Nov 2004

Psoriasis trial enters final stage

Solbec Pharmaceuticals Ltd today announced the successful completion of the first two stages of the Phase I clinical trial of its lead compound, CoramsineTM (SBP002), for the treatment of psoriasis.

4 Nov 2004

New non-invasive diagnostic test for early-stage lung cancer

A non-invasive diagnostic test for early-stage bronchial carcinoma (lung cancer) was presented at White Rose Bioscience Forum in York yesterday (03 November).

4 Nov 2004

Some allergic conditions could increase your risk of suffering from blood cancer

Some allergic conditions could increase your risk of suffering from blood cancer as an adult, according to a new study published in the November 2004 issue of BMC Public Health. This is important news for the increasingly large numbers of allergy sufferers worldwide.

4 Nov 2004

Maxim Pharmaceuticals to withdraw NDA for advanced malignant melanoma

Maxim Pharmaceuticals has announced that based upon the negative outcome of it's confirmatory Phase 3 clinical trial (M0104) studying Ceplene(TM) (histamine dihydrochloride) in combination with Interleukin-2 (IL-2) in advanced malignant melanoma patients with liver metastases, it plans to close the treatment protocol approved by the FDA earlier this year.

2 Nov 2004

Patients are receiving initial diagnosis of celiac disease at an older age

Patients are receiving initial diagnosis of celiac disease at an older age and with a shorter duration of symptoms, according to a retrospective study presented today at the 69th Annual Scientific Meeting of the American College of Gastroenterology.

1 Nov 2004

Alimta approved as first treatment for Mesothelioma, a deadly cancer caused by asbestos

Lilly UK announced today that Alimta( (pemetrexed) will be available shortly for the treatment of people diagnosed with mesothelioma, a cancer of the lining of the lungs for which there is no known cure. Pemetrexed is the first licenced treatment for malignant pleural mesothelioma, in combination with cisplatin.

1 Nov 2004

Ductal lavage is not an effective method for detecting breast cancer

Ductal lavage--a method used to collect cells from the milk ducts of the breast--has been proposed as a screening tool for cancer detection because ducts that yield fluid were thought to be more likely to contain cancer cells.

21 Oct 2004

Tiny beads called microspheres could become the new weapon in the fight against liver cancer

The new treatment involves injecting thousands of the beads via an incision into the hepatic artery - the main blood supply for the liver. When the microspheres are injected they are picked up by the blood flow and eventually lodge in the malignant cells of the tumours.

19 Oct 2004

New genetic mechanism has been identified linking diet to breast cancer

Experiments carried out by scientists at the Universitat Autònoma de Barcelona on experimentally induced breast cancer tumours in laboratory rats show that an excess of certain fats in the diet, commonly known as omega-6, accelerates breast cancer, increasing the malignancy of the disease.

18 Oct 2004

Presentation of the most recent and advanced work in the rapidly progressing field of fertility preservation

Each year approximately 50,000 women under the age of 40 are diagnosed with breast cancer. Treatments vary but most involve the administration of chemotherapeutic agents or radiation which can disrupt ovarian function or damage a patient’s eggs.

18 Oct 2004

Some people who chew betel nut may be genetically more prone to mouth cancer

The nut of the betel or areca palm tree contains a mild, central nervous system stimulant called arecoline. Chewing the nut on its own or with a mixture of tobacco, lime and betel leaf is a popular habit in Asian countries and among British Asians.

12 Oct 2004

Combination of computer science and biology could aid cancer research

The technique helps to show how cells modify their own genetic makeup and may allow cancer treatments to be tailored more precisely to a patient's disease.

11 Oct 2004

Bionanotechnology that combines the strengths of nanotechnology and biochemistry to generate a new type of bionanomaterial

A team of University of Florida researchers has created tiny hybrid particles that can speedily root out even one isolated E. coli bacterium lurking in ground beef or provide a crucial early warning alarm for bacteria used as agents of bioterrorism and for early disease diagnosis.

11 Oct 2004