Mammalian Cells News and Research

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Pioneering technique reveals structure of Parkinson's disease protein in action

The top contributor to familial Parkinson's disease is mutations in leucine-rich repeat kinase 2 (LRRK2), whose large and difficult structure has finally been solved, paving the way for targeted therapies.

16 Feb 2020

MGH researchers uncover potential antiviral drug target for treating infectious diseases

As the coronavirus outbreak shows, viruses are a constant threat to humanity. Vaccines are regularly developed and deployed against specific viruses, but that process takes a lot of time, doesn't help everyone who needs protection, and still leaves people exposed to new outbreaks and new viruses.

11 Feb 2020

Biological toolkit will help researchers design new functions in mammalian cells

A new synthetic biology toolkit developed at Northwestern University will help researchers design mammalian cells with new functionalities.

9 Feb 2020

UH professor examines life cycle of drug-resistant persister cells in recurrent infections

A University of Houston engineering professor is examining the life cycle of stubborn, drug-resistant persister cells in recurrent infections to find a way to destroy them.

4 Feb 2020

Study finds unexpected response to estrogen at the single cell level

A team led by researchers at Baylor College of Medicine found that not only do individual mammalian cells in a population fail to respond synchronously to estrogen stimulation, neither do individual gene copies, known as alleles.

28 Jan 2020

Discovery of metabolic system could lead to new strategies for cancer treatment

Australian researchers have uncovered a metabolic system which could lead to new strategies for therapeutic cancer treatment.

21 Jan 2020

A controlled phage therapy to target drug-resistant pathogens

The fight against drug-resistant pathogens remains an intense one. While the Centers for Disease Control's 2019 "biggest threats" report reveals an overall decrease in drug-resistant microbe-related deaths as compared to its previous report (2013) the agency also cautions that new forms of drug-resistant pathogens are still emerging.

13 Jan 2020

Researchers discover how a new immune system works to protect bacteria from phages

Researchers at University of California San Diego School of Medicine have discovered how a new immune system works to protect bacteria from bacteriophages (phages), viruses that specifically infect bacteria.

11 Jan 2020

Mohamad Khazaei receives SCTM’s Young Investigator Award

Mohamad Khazaei, Ph.D., scientific associate in Dr. Michael Fehlings' lab at Krembil Research Institute, Toronto, is the latest recipient of STEM CELLS Translational Medicine's (SCTM) Young Investigator Award.

9 Jan 2020

Promega and MilliporeSigma sign license agreement to expand the potential of CRISPR

Promega announce license agreement with MilliporeSigma, a leader in genome editing, to access MilliporeSigma’s foundational CRISPR genome-editing technology.

From Promega Corporation 2 Jan 2020

Study provides better understanding of mechanisms that limit cilia number in cells

One of the wonders of cell biology is its symmetry. Mammalian cells have one nucleus and one cell membrane, and most humans have 23 pairs of chromosomes.

30 Dec 2019

New study improves understanding of widespread diseases

When proteins in the brain form deposits consisting of insoluble aggregates, diseases such as Alzheimer's or Parkinson's can occur. Now a research team has come a step closer to understanding this process.

14 Dec 2019

Unexpected versatility of an ancient DNA repair factor revealed

If a bone breaks or a tendon snaps, you know to seek treatment immediately. But your most fragile and precious cellular commodity, chromosomal DNA, breaks with astounding frequency- some estimate as many as 10,000 times a day per cell- usually without consequence.

2 Dec 2019

Research shows how cilia and exocyst contribute to extracellular vesicle production

Although the cilium has been known to scientists for more than 100 years, it is only recently that it has been acknowledged to play important roles in physiology.

25 Nov 2019

Porvair Sciences offers fast and efficient Chromatrap Protein Extraction kit

The Chromatrap Protein Extraction kit from Porvair Sciences offers a fast and efficient method of extracting cytoplasmic, nuclear or total protein from mammalian cells.

From Porvair Sciences Limited 8 Nov 2019

Sphere Fluidics and Peak Analysis and Automation introduce integrated micro-plate handling and single cell analysis capabilities

Sphere Fluidics and Peak Analysis and Automation, announce optimization of the Single Cell Analysis System through integration with automated plate handler.

From Sphere Fluidics 7 Nov 2019

Researchers develop new type of transposase protein with improved biochemical properties

The team, comprising researchers from the European Molecular Biology Laboratory, the Universitätsklinikum Würzburg and the Paul-Ehrlich-Institut, managed to design a new variant of the Sleeping Beauty transposase with dramatically improved biochemical properties.

4 Nov 2019