Mammalian Cells News and Research

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Human immune system in a test tube

Surgical instruments or implants that are contaminated with residual bacteria, or pyrogens, can cause blood poisoning in patients. Researchers are developing a test that imitates the human immune system in the laboratory, eliminating the need for animal experiments.

4 Jul 2007

Microinjection of live single cells

Specialized pulsed lasers have been used to inject individual cells with a variety of materials, but little is known about how this type of injection might affect living cells.

17 Jun 2007

Researchers shed light on shrinking of chromosomes

A human cell contains an enormous 1.8 metres of DNA partitioned into 46 chromosomes.

15 Jun 2007

Interfacing silicon nanowires with mammalian cells

A research team at the University of California, Berkeley, has achieved a significant step toward one of the futuristic goals of nanomedicine and nanobiology-developing technology for "wiring" together individual cells.

14 Jun 2007

Researchers explore the glycosylation process

By studying the addition of sugars to proteins — a process called glycosylation — in the nervous system of insects, Temple University researcher Karen Palter believes she may be able to better understand neurodegenerative diseases in humans.

28 May 2007

Study finds large number of new proteins implicated in Huntington's disease

Researchers from four organizations have identified more than 200 new proteins that bind to normal and mutant forms of the protein that causes Huntington's disease (HD).

11 May 2007

New compounds promising candidates for neurodegenerative disease drug development

Scientists have developed a novel strategy for tackling neurodegenerative diseases such as Huntington's disease: encouraging an individual's own cells to "eat" the malformed proteins that lead to the disease.

8 May 2007

Method of mass-producing disease-fighting antibodies entirely within bacteria

The group led by Dr. George Georgiou developed the new antibody-production approach to improve upon processes used previously to identify new drugs.

19 Apr 2007

Study provides first direct link between plants and humans

The study was published in an advance online edition of the Proceedings of the National Academy of Sciences during the week of April 9, 2007.

10 Apr 2007

New therapeutic target for Alzheimer's could lead to drugs without side effects

It's been 100 years since Alzheimer's disease was first described, and yet our best treatments in development for the disease are still highly toxic drugs.

5 Apr 2007

Bacteria biosensor prototype

Common bacteria with an overt reaction to toxins that cause oxidative stress show promise as a biosensor to predict public health threats.

2 Apr 2007

Sigma-Aldrich grants Pfizer license to use ddRNAi

Sigma-Aldrich has announced that it has granted Pfizer a worldwide non-exclusive research license to utilize DNA-directed RNAi (ddRNAi) technology. Applications of the ddRNAi technology for research activities have been licensed exclusively by Sigma- Aldrich from Benitec Limited of Australia.

3 Jan 2007

Scientists discover function for antisense RNA

Researchers have found that a class of RNA molecules, previously thought to have no function, may in fact protect sex cells from self-destructing. These findings will be published in the November 17 issue of the journal Cell.

20 Nov 2006

Lab-on-a-chip nanoscale array monitors cellular processes

Researchers at Tel-Aviv University in Israel have developed a lab-on-a-chip device that can incorporate enzymes and even living cells in a nanoscale array capable of monitoring electrochemical reactions.

30 Oct 2006

Scientists discover two proteins responsible for detecting sour tastes

A team led by Duke University Medical Center researchers has discovered two proteins in the taste buds on the surface of the tongue that are responsible for detecting sour tastes.

7 Aug 2006

Txr1 gene that affects human cancer cells' sensitivity to chemotherapy

Gene that affects human cancer cells' sensitivity to chemotherapy - an important finding in the effort to increase the effectiveness of chemotherapy.

6 Aug 2006

In vivo, in vitro, in silico

Prof. Jens Reich, Biomathematician and member of the German National Ethics Council, is one of the scientists within the Systems Biology competence network HepatoSys who is on the scent of a major mystery of life.

17 May 2006

New Hybrid virus may aid treatment of cancer

Researchers at The University of Texas M. D. Anderson Cancer Center have created a new class of hybrid virus and demonstrated its ability to find, highlight, and deliver genes to tumors in mice.

26 Apr 2006

Important new global mechanism for gene repression

Most of the time in most cells of the body, the great majority of genes are silenced, locked away within the compacted but orderly material that makes up chromosomes.

18 Apr 2006

Whole genome analysis of the protein kinases from Dictyostelium

The journal PLoS Genetics has published the findings of a team of scientists at the nonprofit Boston Biomedical Research Institute that provides a whole genome analysis of the protein kinases from a scientifically valuable model organism known as Dictyostelium.

10 Apr 2006