Mammary Gland News and Research

RSS

Mothers with preeclampsia at reduced risk of developing breast cancer

Preeclampsia is a high blood pressure syndrome in pregnant mothers that is caused when the blood supply in the placenta of the developing baby is restricted. The blood-deprived placenta releases factors that cause the raise in blood pressure in the mother. Doctors have to monitor these women closely and they may be forced to deliver the baby early to protect the mother and the baby. Most women's blood pressure returns to normal levels after they deliver the placenta.

26 Apr 2010

Environmental factors may play bigger role in tumor development: BIDMC study

It is an accepted fact that genetics play a key role in a person's susceptibility to cancer, and that throughout life, mutations can cause damage to tumor suppressor genes further increasing the chances of developing cancerous tumors.

24 Apr 2010

Exposure to certain chemicals may lead to early pubertal development

Researchers at Mount Sinai School of Medicine have found that exposure to three common chemical classes-phenols, phthalates and phytoestrogens-in young girls may disrupt the timing of pubertal development, and put girls at risk for health complications later in life.

6 Apr 2010

Social isolation and stress can raise breast cancer risk

Social isolation and related stress could contribute to human breast cancer susceptibility, research from a rat model designed at the University of Chicago to identify environmental mechanisms contributing to cancer risk shows.

8 Dec 2009

Enzyme that plays an important role in the formation of breast tumours identified

A team of US scientists found that the enzyme lysyl oxidase (LOX) alters the structure of collagen - the major component of connective tissue - in the cells surrounding the growing tumour.

25 Nov 2009

New gene therapy may breach the armor of cancerous tumors

The seeming invincibility of cancerous tumors may be crumbling, thanks to a promising new gene therapy that eliminates the ability of certain cells to repair themselves. Researchers at the Cornell University College of Veterinary Medicine have discovered that inactivation of a DNA repair gene called Hus1 efficiently kills cells lacking p53 -- a gene mutated in the majority of human cancers.

13 Nov 2009

NIEHS supports research to study the potential effects of BPA on human health

Researchers studying the health effects of the chemical bisphenol A (BPA) gathered in North Carolina to launch an integrated research initiative to produce data that will allow for a comprehensive assessment of its possible human health effects.

29 Oct 2009

Study on Pten's tumour suppressive functions published

Sanford Barsky, M.D., who holds faculty positions at the University of Nevada School of Medicine as chair of the pathology department and Nevada Cancer Institute chief of pathology, is part of a team that has a paper on transgenic mouse mammary tumors with direct relevance to human breast cancer published in the October 22 issue of the scientific journal Nature.

24 Oct 2009

Social environment plays vital role in breast cancer

Social environment can play an important role in the biology of disease, including breast cancer, and lead to significant differences in health outcome, according to results of a study published in Cancer Prevention Research, a journal of the American Association for Cancer Research.

1 Oct 2009

Study suspects involvement of PPAR-γ in gastric carcinogenesis

Recently, the potential of PPAR-γ as a target for the prevention and treatment of cancer has been widely studied. However, the potential therapeutic role of PPAR-γ agonists has been questioned, based on contradictory results. Studies using animal models of colon cancer found that PPAR-γ agonists increased the development of colon tumors.

27 Aug 2009

Study finds long-term exposure to progesterone may lead to growth of tumors

Scientists at Michigan State University have found exposure to the hormone progesterone activates genes that trigger inflammation in the mammary gland.

20 Aug 2009

Discovery of four new breast cancer targets

Four suspects often found at the scene of the crime in cancer are guilty of the initiation and progression of breast cancer in mice that are resistant to the disease, a team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in the June edition of Cancer Cell.

10 Jun 2009

Dioxins in food chain linked to breastfeeding problems

Exposure to dioxins during pregnancy harms the cells in rapidly-changing breast tissue, which may explain why some women have trouble breastfeeding or don’t produce enough milk, according to a University of Rochester Medical Center study.

9 Jun 2009

New DEAR1 gene predicts local recurrence in early-onset breast cancer

A newly discovered gene known as DEAR1 is mutated in breast cancer and is an independent predictor of local recurrence-free survival in early-onset breast cancer, a research team headed by scientists at The University of Texas M. D. Anderson Cancer Center reports in the journal PLoS Medicine.

5 May 2009

Rak gene helps protect tumor suppressor in breast cancer

Scientists at The University of Texas M. D. Anderson Cancer Center have discovered a gene that protects PTEN, a major tumor-suppressor that is reduced but rarely mutated in about half of all breast cancers.

6 Apr 2009

New technique to view labeled tumor cells in 'real' time

A breakthrough technique that allows scientists to view individually-labeled tumor cells as they move about in real time in a live mouse may enable scientists to develop microenvironment-specific drugs against cancer, researchers report at the American Society for Cell Biology (ASCB) 48th Annual Meeting, Dec. 13-17, 2008 in San Francisco.

15 Dec 2008

Eating eggs when pregnant may help prevent breast cancer in offspring

A stunning discovery based on epigenetics (the inheritance of propensities acquired in the womb) reveals that consuming choline - a nutrient found in eggs and other foods - during pregnancy may significantly affect breast cancer outcomes for a mother's offspring.

1 Dec 2008

Grant funds research on environmental link to breast cancer

A foundation that funds research that examines the environmental causes of breast cancer has awarded a grant to a post-doctoral associate at the University of Rochester Medical Center.

23 Oct 2008

Scientists grow prostates from mouse stem cells

A team of molecular biologists in the U.S. have grown complete prostates derived from stem cells in the prostates of mice and they say the experiment represents a big step towards regenerating organs from a patients' own cells.

23 Oct 2008

National Toxicology Program finalizes report on Bisphenol A

Current human exposure to bisphenol A (BPA), a chemical used in many polycarbonate plastics and epoxy resins, is of "some concern" for effects on development of the prostate gland and brain and for behavioral effects in fetuses, infants and children, according to a final report released today by the National Toxicology Program (NTP).

3 Sep 2008