Mass Spectrometry News and Research

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Mass spectrometry is an analytical method used to identify different compounds based on the atomic sample constitution of the molecules and their charge state, which enables “blind” analysis of an unknown sample without any prior knowledge of its composition.

Quantitative phosphoproteomic approach to identify targeted cancer therapy

Winner of the Louise Eisenhardt Traveling Scholarship Award, Teresa Purzner, MD, presented her research, Quantitative Phosphoproteomics for Targeted Cancer Therapy.

7 May 2015

Proteomics helps identify previously unrecognized proteins and pathways in nerve regeneration

Using proteomics techniques to study injured optic nerves, researchers at Boston Children's Hospital have identified previously unrecognized proteins and pathways involved in nerve regeneration. Adding back one of these proteins--the oncogene c-myc--they achieved unprecedented optic nerve regeneration in mice when combined with two other known strategies.

5 May 2015

Max Planck Institute researchers find protein profiles of DNA repair

During each cell division, more than 3.3 billion base pairs of genomic DNA have to be duplicated and segregated accurately to daughter cells. But what happens when the DNA template is damaged in such a way that the replication machinery gets stuck? To answer this question, scientists in the team of Matthias Mann at the Max Planck Institute of Biochemistry in Martinsried near Munich, with colleagues in Copenhagen and at Harvard, have analyzed how the protein composition of the DNA replication machinery changes upon encountering damaged DNA.

5 May 2015

US Liquid Handling Market estimated to reach $974 million in 2021

The trend of laboratories moving from manual methods to automated workflows is advancing momentum in the uptake of liquid handling instruments in the U.S. Stricter regulations and a growing focus on data precision, efficiency and reproducibility are driving the transition to automation in liquid handling.

29 Apr 2015

TUW, Medical University of Vienna jointly develop artificial blood vessels from elastomer material

Blocked blood vessels can quickly become dangerous. It is often necessary to replace a blood vessel - either by another vessel taken from the body or even by artificial vascular prostheses. Together, Vienna University of Technology and Vienna Medical University have developed artificial blood vessels made from a special elastomer material, which has excellent mechanical properties.

28 Apr 2015

Manchester scientists make key finding that could help deliver early test for kidney disease

Scientists at The University of Manchester have made an important finding that could help develop an early test for kidney disease.

22 Apr 2015

Women in science: an interview with Professor Dame Carol Robinson, University of Oxford

Professor Dame Carol Robinson has just been announced as the “L’Oréal-UNESCO For Women In Science” European Laureate for 2015...

14 Apr 2015

Analytical innovations top $10M in licensing income for PNNL, Battelle

A suite of analytical innovations used to detect and measure very low levels of compounds and elements for environmental, national security and health applications has topped $10 million in licensing income for Pacific Northwest National Laboratory and its operator Battelle.

3 Apr 2015

Researchers create 3D skin maps to detect molecular, microbial variations across the body

Researchers at the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences used information collected from hundreds of skin swabs to produce three-dimensional maps of molecular and microbial variations across the body.

31 Mar 2015

Investigational S-equol nutritional supplement may alleviate certain menopause symptoms

The investigational S-equol nutritional supplement may be a viable agent to alleviate certain menopause symptoms, such as hot flashes, according to a new peer-reviewed article in the March Journal of Women's Health.

30 Mar 2015

Thermo Fisher Scientific to resell Prosolia’s PaperSpray® technology as factory option to its mass spectrometers

Labs performing clinical research and forensic toxicology of dried sample spots can now purchase Thermo Scientific mass spectrometry (MS) systems equipped from the factory with PaperSpray technology, designed to virtually eliminate sample preparation for screening and quantitation of drugs in biological fluid samples.

From Thermo Fisher Scientific Inc. 30 Mar 2015

Denator partners with Maastricht University to develop sample stabilization approaches for clinical applications

Denator AB announced today that the company has entered into a 2-year collaboration with the Maastricht MultiModal Molecular Imaging Institute (M4I) of Maastricht University, the Netherlands. As part of the collaboration, Denator will work closely with the M4I Division of Imaging Mass Spectrometry, headed by university professor Ron Heeren, to jointly develop and evaluate innovative sample stabilization approaches for clinical applications.

26 Mar 2015

Agena Bioscience releases LungFUSION Panel to identify gene fusions in NSCLC tumors

Agena Bioscience today released the LungFUSION Panel for rapid and sensitive identification of oncogenic ALK, RET, and ROS1 gene fusions in non-small cell lung cancer tumors.

25 Mar 2015

RNA molecule can be manipulated to generate more neurons from neural stem cells

A research team at UC San Francisco has discovered an RNA molecule called Pnky that can be manipulated to increase the production of neurons from neural stem cells.

20 Mar 2015

AbbVie signs exclusive worldwide license agreement with C2N for Alzheimer's disease therapies

AbbVie today announced that it has entered into an exclusive worldwide license agreement with C2N Diagnostics, a privately held protein diagnostic and therapeutic discovery company, to develop and commercialize a portfolio of anti-tau antibodies for the treatment of Alzheimer's Disease and other neurological disorders.

19 Mar 2015

Denator's heat-stabilization system preserves lipids at close-to-in vivo-levels

Denator AB announced today that the company’s heat-stabilization system has been demonstrated to preserve lipids at close-to-in vivo-levels. To preserve lipids in a reliable manner prior to mass spectrometry-based analysis is pivotal to accurately quantify and identify potential biomarkers and perform disease research.

19 Mar 2015

Researchers discover new metabolic mechanisms linked to macrophage polarization

A group of researchers from Washington University in St. Louis, Agios Pharmaceuticals and ITMO University has discovered new metabolic mechanisms that regulate macrophage polarization - the unique ability of these immune cells to change their specialization depending on the required task.

18 Mar 2015

Hydrazine not prevalent in smokeless tobacco products

After many years of speculation, it has finally been established that hydrazine is not a prevalent contaminant in contemporary smokeless tobacco products (STPs).

18 Mar 2015

Pressure BioSciences introduces PCT-HD System to global proteomics market

Pressure BioSciences, Inc., a leader in the development and sale of broadly enabling, pressure cycling technology ("PCT")-based sample preparation solutions to the worldwide life sciences industry, today announced the commercial release of the PCT-HD system.

12 Mar 2015

Researchers develop robust screening method for routine measurement of drugs in exhaled breath

Drug testing is most commonly performed using urine samples. The methodology and regulations for reliable urine testing are well developed and can be considered the current gold standard for drug testing.

9 Mar 2015