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Discovery of genetic mutations that increase risk of schizophrenia

In collaboration with colleagues from across Europe, researchers from the University of Copenhagen and the Mental Health Services in the Capital Region of Denmark have found mutations in the human genome that lead to an increased risk of developing schizophrenia.

11 Aug 2009

Experimental treatment for multiple sclerosis reverses disorder in mice

A new experimental treatment for multiple sclerosis (MS) completely reverses the devastating autoimmune disorder in mice, and might work exactly the same way in humans, say researchers at the Jewish General Hospital Lady Davis Institute for Medical Research and McGill University in Montreal.

11 Aug 2009

Integrated Medical Systems receives U.S. Army order for "suitcase" intensive care unit

Integrated Medical Systems, Inc., a medical technology systems integrator transforming critical care, announced that it has received a commitment for approximately $3.25 million in funding from the U.S. Army's Medical Research Material Command for acquisition and ongoing development of the company's MedEx 1000(TM) "suitcase" intensive care unit (ICU).

11 Aug 2009

Oxygen nanosensor could improve tumor imaging

A new material developed at the University of Virginia - an oxygen nanosensor that couples a light-emitting dye with a biopolymer - simplifies the imaging of oxygen-deficient regions of tumors. Such tumors are associated with increased cancer aggressiveness and are particularly difficult to treat.

11 Aug 2009

New class of molecules capable of blocking formation of tau protein fibrils

A new class of molecules capable of blocking the formation of specific protein clumps that are believed to contribute to Alzheimer’s disease pathology has been discovered by researchers at the University of Pennsylvania School of Medicine. By assaying close to 300,000 compounds, they have identified drug-like inhibitors of AD tau protein clumping, as reported in the journal Biochemistry.

11 Aug 2009

'Nanobee' drug delivery to tumors

When bees sting, they pump poison into their victims. Now the toxin in bee venom has been harnessed to kill tumor cells by researchers at Washington University School of Medicine in St. Louis. The researchers attached the major component of bee venom to nano-sized spheres that they call nanobees.

11 Aug 2009

Burnham as a comprehensive center in a new National Cancer Institute (NCI) Chemical Biology Consortium

The consortium will establish a new paradigm in the use of public-private partnerships to translate knowledge from leading academic institutions into new drug treatments for patients with cancer. Both the La Jolla, Calif. campus of Burnham and its new Lake Nona campus in Orlando, Fla. will participate in the consortium.

10 Aug 2009

Senators Harkin, Kennedy and Specter honored as champions of health research

The Foundation for the National Institutes of Health, Research!America and the Albert and Mary Lasker Foundation recognized these three senators for their continued support of research for health, their leadership and shared commitment to making it a high national priority, on Tuesday evening August 4th at the Russell Senate Office Building.

6 Aug 2009

Percutaneous vertebroplasty exposed as ineffective

A world-first study involving Monash University and the Cabrini Research Institute in Melbourne has revealed the injection of bone cement into broken vertebrae is not an effective treatment for patients suffering painful osteoporotic fractures.

6 Aug 2009

Discovery of new gene mutations linked to leukemia

Decoding the complete DNA of cancer patients is giving scientists at Washington University School of Medicine in St. Louis a clearer picture of the complexity of the disease and allowing them to see intriguing and unexpected genetic relationships among patients.

5 Aug 2009

New discovery about dystonia

Most people who carry a genetic mutation for a movement disorder called dystonia will never develop symptoms, a phenomenon that has puzzled scientists since the first genetic mutation was identified in the 1990's.

5 Aug 2009

Research looks at cellular stress response to low oxygen

Gary Chiang, Ph.D., and colleagues at Burnham Institute for Medical Research (Burnham) have elucidated how the stability of the REDD1 protein is regulated. The REDD1 protein is a critical inhibitor of the mTOR signaling pathway, which controls cell growth and proliferation.

5 Aug 2009

Cutting-edge imaging research aims to map brain injuries

In the first study of its kind, researchers at Saint Louis University are recruiting patients for a clinical trial that will use cutting-edge imaging equipment to map the brain injuries of combat veterans and civilians, aiming to better understand the nature of their injuries.

5 Aug 2009

Seed implants suitable prostate cancer treatment for men of all ages

Men diagnosed with prostate cancer have a number of treatments to choose from, but it's a daunting task to figure out the right mix of therapies for an individual patient.

3 Aug 2009

Nanoparticles show potential as part of new therapy for advanced ovarian cancer

Nanoparticle delivery of diphtheria toxin-encoding DNA selectively expressed in ovarian cancer cells reduced the burden of ovarian tumors in mice, and researchers expect this therapy could be tested in humans within 18 to 24 months, according to a report in Cancer Research, a journal of the American Association for Cancer Research.

30 Jul 2009

Plenty of dairy foods in childhood may mean a longer life

Milk is an excellent source of calcium and the children who ate plenty of dairy foods such as milk and cheese appeared to be protected against stroke and other causes of death, even though dairy products often contain fats and cholesterol which fur up the arteries and high consumption of dairy products did not raise the heart disease risk.

28 Jul 2009

Hypertension may lead to ‘silent’ strokes

"Silent" strokes, which are strokes that don't result in any noticeable symptoms but cause brain damage, are common in people over 60, and especially in those with high blood pressure, according to a study published in the July 28, 2009, print issue of Neurology, the medical journal of the American Academy of Neurology.

28 Jul 2009

Diets high in calcium and dairy products in childhood may lower mortality

Suggestive evidence points to the possibility that children who have a diet high in calcium and who consume dairy products may have a lower mortality rate than those who don't, according to a study by researchers in Bristol and Brisbane, published in the journal Heart.

27 Jul 2009

Caspase-8 protein plays an important role in proliferation and invasion of cancer cells

Scientists at Burnham Institute for Medical Research have found that the Caspase-8 protein, long known to play a major role in promoting programmed cell death (apoptosis), helps relay signals that can cause cancer cells to proliferate, migrate and invade surrounding tissues. The study was published in the journal Cancer Research on June 15.

24 Jul 2009

New drug may reduce heart attack damage

A novel drug that targets a master disease-causing gene can dramatically reduce heart muscle damage after a heart attack and may lead to significantly improved patient outcomes, researchers at the University of New South Wales (UNSW) have shown.

22 Jul 2009