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Atypical hyperplasia increases risk of developing breast cancer

A type of benign breast disease (BBD) known as atypical hyperplasia substantially increases a young woman's risk of developing breast cancer, even if there is no history of breast cancer in her family, say researchers at Mayo Clinic.

14 Dec 2008

Six new gene variations linked to increased BMI

A genetic study of more than 90,000 people has identified six new genetic variants that are associated with increased Body Mass Index (BMI), the most commonly used measure of obesity.

14 Dec 2008

Neither vitamin E nor selenium reduce risk of prostate cancer

In perhaps the largest cancer chemoprevention trial ever conducted, researchers have found that supplementation with vitamin E or selenium, alone or in combination, was not associated with a lower risk of prostate cancer or other cancers.

10 Dec 2008

People who want access to the NHS should behave more responsibly, says expert

Patients should recognise they have to take responsibility for their own health if they want access to free healthcare, says a leading academic.

10 Dec 2008

Conquering cancer: A global effort

Despite the recent good news that cancer incidence and death rates for men and women in the United States continue to decline, cancer is projected to become the leading cause of death worldwide in the year 2010, and low- and middle-income countries will feel the impact of higher cancer incidence and death rates more sharply than industrialized countries.

10 Dec 2008

Computation and genomics data drive bacterial research into new golden age

A potent combination of powerful new analysis methods and abundant data from genomics projects is carrying microbiology forward into a new era.

10 Dec 2008

Promising trials of malaria vaccine in East Africa lead to calls for phase 3 development

Experts are recommending that a malaria vaccine progress to Phase 3 trials following the successful trial of the RTS, S/AS01E malaria vaccine among 5-17 month old children in Korogwe, Tanzania and coastal Kenya, which is reported in the New England Journal of Medicine (NEJM).

8 Dec 2008

Anti-seizure drug Epilim shows promise for Alzheimer's

A drug commonly used to treat epilepsy could help clear the plaques in the brain associated with Alzheimer's disease, according to researchers at the University of Leeds. The plaques are known to lead to the progressive death of nerve cells in the brain linked to many forms of dementia.

8 Dec 2008

Clinical study shows that drug improves endothelial function in sickle cell disease patients

Itamar Medical, an international medical technology company developing noninvasive diagnostic technology using the Peripheral Arterial Tone (PAT) Signal, announced today the use of the company's patented Endo-PAT2000 in BioMarin Pharmaceutical Inc.'s phase 2 study of patients with Sickle Cell Disease (SCD). The Endo-PAT2000 was used to measure endothelial function in a study designed to evaluate whether the drug 6R-BH4 can improve endothelial function in SCD patients

5 Dec 2008

New insights into development of the human immune system

A UCSF study has found that a surprisingly high number of maternal cells enters the fetus during pregnancy, prompting the generation of special immune cells in the fetus that suppress a response against the mother.

5 Dec 2008

Breakthrough in understanding the phenomenon of nucleolar dominance

Since the machinery involved in nucleolar dominance is some of the same machinery that can go haywire in diseases such as cancer, Pikaard and his collaborators' research may have important implications for applied medical research.

5 Dec 2008

Discovery of groundbreaking technique for body to accept gene therapy

Researchers at Columbia University Medical Center and the State University of New York at Stony Brook (SUNY) have developed a groundbreaking technique to sneak therapeutic genes past the body's defenses, possibly clearing one of the largest hurdles to realizing the potentials of medically altering a patient's DNA.

5 Dec 2008

Scientists film immune cell becoming infected by a parasite

Forget what's number one at the box office this week. The most exciting new film features the intricate workings of the body, filmed by scientists using ground-breaking technology.

3 Dec 2008

Young researcher identifies binocular vision gene

Dr Catherine Leamey from the School of Medical Sciences at the University of Sydney has been awarded the 2008 Sir Zelman Cowen Universities Fund Prize for Medical Research for her work in identifying the gene that enables binocular vision.

3 Dec 2008

Fruit flies provide better understanding of human heart disease

Researchers at the Burnham Institute for Medical Research have shown in both fruit flies and humans that genes involved in embryonic heart development are also integral to adult heart function.

3 Dec 2008

Worrying about your health? more government money will help you stay well

A national poll by the Australian medical research body, Research Australia, has found that many Australians are worried about developing a range of chronic diseases during their lifetime, particularly diseases such as arthritis.

2 Dec 2008

Protein indoleamine 2,3-dioxygenase points to new pancreatic cancer therapies

An enzyme that is overexpressed in pancreatic cancer cells may hold the key to successfully treating the disease with targeted immunotherapy, researchers from Thomas Jefferson University reported at the 2008 Annual Meeting of the Southern Surgical Association.

1 Dec 2008