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Isis Pharma announces ISIS-CRPRx Phase 1 trial results in diseases with elevated CRP

Isis Pharmaceuticals, Inc. announced today the results from a Phase 1 clinical trial in which ISIS-CRPRx produced statistically significant reductions in C-reactive protein in the cohort of subjects in the study with elevated CRP.

24 Feb 2011

New study: Surgeon annual volume linked to decreased in-hospital mortality for aneurysm repairs

A new study in the March 2011 issue of the Journal of Vascular Surgery, the official publication of the Society for Vascular Surgery, has revealed that for open repair of intact elective abdominal aortic aneurysms, surgeon annual volume rather than institutional volume is more strongly associated with decreased in-hospital mortality.

24 Feb 2011

New research: Spinal fluid proteins can differentiate nPTLS from Chronic Fatigue Syndrome

Patients who suffer from Neurologic Post Treatment Lyme disease and those with the Chronic Fatigue Syndrome report similar symptoms. However unique proteins discovered in spinal fluid can distinguish those two groups from one another and also from people in normal health, according to new research conducted by a team led by Steven E. Schutzer, MD, of the University of Medicine and Dentistry of New Jersey - New Jersey Medical School, and Richard D. Smith, Ph.D., of Pacific Northwest National Laboratory.

24 Feb 2011

Pretreatment with FDA-approved drug allows successful pregnancies in radiation-exposed rhesus monkeys

A strategy developed by Massachusetts General Hospital (MGH) researchers to shield the ovaries of female mammals from the damaging effects of radiation and chemotherapy has passed an important milestone. A collaborative study with investigators from Oregon Health and Sciences University (OHSU), published online in the journal Fertility and Sterility, reports that brief preexposure of the ovaries to an FDA-approved agent called FTY720 preserved the fertility of female rhesus monkeys exposed to potentially lethal doses of radiation.

23 Feb 2011

OptumHealth names Women & Infants Hospital of Rhode Island as Center of Excellence for Neonatal Care

For the fifth consecutive year, Women & Infants Hospital of Rhode Island has been named a Center of Excellence for Neonatal Care by the Clinical Sciences Institute of OptumHealth, an independent audit company. According to OptumHealth, not all health care providers are created equal. For complex medical conditions, the disparity is especially high.

23 Feb 2011

'Day on Deadly Killers'

Experts from Europe, the US and Asia will present their research results and discuss how new therapeutical approaches against infectious diseases may look like.

22 Feb 2011

Infinity commences IPI-926 Phase 2 trial in patients with pancreatic cancer

Infinity Pharmaceuticals, Inc. today announced the initiation of the randomized Phase 2 portion of the trial of IPI-926 in combination with gemcitabine in patients with previously untreated, metastatic, pancreatic cancer.

22 Feb 2011

Caution on mammograms for breast cancer survivors: Study

A new study finds that in women who have had breast cancer, annual mammograms help detect second breast cancers, but they are not as effective in women who have never had the disease.

22 Feb 2011

Mutated cancer pathway studies identify therapeutic targets for congenital heart disease

Cross-disciplinary teams of scientists studying genetic pathways that are mutated in many forms of cancer, but which also cause certain forms of congenital heart disease - including hypertrophic cardiomyopathy, a thickening of the heart muscle that is the leading cause of sudden death in children and young adults -, have introduced these mutations into mice and successfully treated HCM in the lab.

22 Feb 2011

Positive preliminary data from Fate Therapeutics FT1050 Phase 1b trial in patients with life-threatening conditions

Fate Therapeutics, Inc. presented encouraging preliminary data from an ongoing Phase 1b clinical trial of FT1050 at the 2011 BMT Tandem Meetings in Honolulu, Hawaii.

22 Feb 2011

New study: Rapamycin reverses cardiac muscle damage in LEOPARD syndrome mouse model

Congenital heart diseases affect approximately one in 100 patients, making them the most common type of birth defect and the number-one cause of pediatric deaths.

21 Feb 2011

Loyola forms new sixth research-focused transplant institute at LUHS

From the world's first successful kidney transplant to the first successful heart transplant performed in Illinois, Loyola University Health System has always been a pioneer in organ transplant research, education and clinical care.

21 Feb 2011

Genzyme reports 3-year follow-up data from eliglustat tartrate Phase 2 trial for Gaucher disease

Genzyme Corporation today announced three-year follow-up data from patients enrolled in the phase 2 clinical trial for its investigational oral therapy for Gaucher disease type 1 known as eliglustat tartrate. Sustained or further improvements were observed across all endpoints, including bone disease, at the three-year timepoint.

19 Feb 2011

NSBRI awards four scientists with postdoctoral fellowships for space-related biomedical research

Four young scientists are now conducting research to help protect astronaut health. The researchers are recipients of postdoctoral fellowships awarded by the National Space Biomedical Research Institute.

19 Feb 2011

New studies unveil latest information on hip care at AAOS meeting

At today's 2011 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) three new studies unveil the latest in hip care.

19 Feb 2011

Medical students can bebefit from ACMG Summer Genetics Scholar Program

Medical students from around the country will have an opportunity to experience firsthand the new frontier of medicine in a revolutionary new genetics summer training program just announced by the American College of Medical Genetics Foundation, a prominent non-profit genetics foundation.

19 Feb 2011

Deep brain stimulation therapy promising against severe OCD

When obsessive-compulsive disorder is of crippling severity and drugs and behavior therapy can't help, there has been for just over a year a thread - or rather a wire - of hope. By inserting a thin electrode deep into the brain, doctors can precisely deliver an electrical current to a cord of the brain's wiring and soften the severity of the symptoms. "Deep brain stimulation" therapy for OCD won Food and Drug Administration approval in 2009 for extreme cases under its humanitarian device exemption.

19 Feb 2011

Depression doesn't decline with age in addiction-prone women

Unlike alcohol abuse problems and antisocial behavior, depression doesn't decline with age in addiction-prone women in their 30s and 40s - it continues to increase, a new study led by University of Michigan Health System researchers found.

18 Feb 2011

Frequent, potentially avoidable readmissions are major driver of pediatric health care costs

Among a group of children's hospitals, nearly 20 percent of admissions and one-quarter of inpatient expenditures were accounted for by a small percentage of patients who have frequent recurrent admissions, according to a study in the February 16 issue of JAMA.

18 Feb 2011

World's first cancer stem cell-targeting chemical missile

Deakin University medical scientists have created the world's first cancer stem cell-targeting chemical missile, placing them a step closer to creating a medical 'smart bomb' that would seek out and eradicate the root of cancer cells.

18 Feb 2011

Medical School News and Research

Isis Pharma announces ISIS-CRPRx Phase 1 trial results in diseases with elevated CRP

New study: Surgeon annual volume linked to decreased in-hospital mortality for aneurysm repairs

New research: Spinal fluid proteins can differentiate nPTLS from Chronic Fatigue Syndrome

Pretreatment with FDA-approved drug allows successful pregnancies in radiation-exposed rhesus monkeys

OptumHealth names Women & Infants Hospital of Rhode Island as Center of Excellence for Neonatal Care

'Day on Deadly Killers'

Infinity commences IPI-926 Phase 2 trial in patients with pancreatic cancer

Caution on mammograms for breast cancer survivors: Study

Mutated cancer pathway studies identify therapeutic targets for congenital heart disease

Positive preliminary data from Fate Therapeutics FT1050 Phase 1b trial in patients with life-threatening conditions

New study: Rapamycin reverses cardiac muscle damage in LEOPARD syndrome mouse model

Loyola forms new sixth research-focused transplant institute at LUHS

Genzyme reports 3-year follow-up data from eliglustat tartrate Phase 2 trial for Gaucher disease

NSBRI awards four scientists with postdoctoral fellowships for space-related biomedical research

New studies unveil latest information on hip care at AAOS meeting

Medical students can bebefit from ACMG Summer Genetics Scholar Program

Deep brain stimulation therapy promising against severe OCD

Depression doesn't decline with age in addiction-prone women

Frequent, potentially avoidable readmissions are major driver of pediatric health care costs

World's first cancer stem cell-targeting chemical missile

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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