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UIC scientists identify hidden proteins in bacteria

Scientists at the University of Illinois at Chicago have developed a way to identify the beginning of every gene -- known as a translation start site or a start codon -- in bacterial cell DNA with a single experiment and, through this method, they have shown that an individual gene is capable of coding for more than one protein.

21 Mar 2019

GARDP and Evotec partner to tackle growing threat of antimicrobial resistance

The Global Antibiotic Research and Development Partnership and Evotec AG are today announcing the formation of a new strategic public-private partnership to tackle the growing threat of antimicrobial resistance.

19 Mar 2019

Bacteria from seawater provide new leads to treat malignant melanoma

Malignant melanoma can be a particularly dangerous form of cancer, and more therapeutic options are needed. Now, researchers report in ACS Medicinal Chemistry Letters that a bacteria from seawater has inspired promising leads for an entirely new way to treat the disease.

7 Mar 2019

New technique could expedite cancer diagnosis, lead to better patient outcomes

The days - or even weeks - spent waiting for the results of a cancer-screening test can feel like an eternity. Especially when early diagnosis and quick action are tied to better outcomes.

20 Feb 2019

Metrion collaborates with LifeArc on neuroscience-focused ion channel drug discovery project

Metrion Biosciences and LifeArc have entered into a collaboration agreement for an ion channel drug discovery project in the field of neuroscience.

From Metrion Biosciences Limited 30 Jan 2019

University of Nebraska to develop new drugs that prevent and counteract effects of radiation exposure

The U.S. Department of Defense has turned to the University of Nebraska to jumpstart the development of drug therapies to protect military service members from the effects of radiation exposure.

16 Jan 2019

New anti-Wolbachia drug could potentially treat onchocerciasis and lymphatic filariasis

Researchers from LSTM and the University of Liverpool have successfully optimized a hit from a whole cell screening of a 10000-compound library to deliver the first novel fully synthetic and rationally designed anti-Wolbachia drug, AWZ1066S, which could potentially be used to treat onchocerciasis and lymphatic filariasis.

8 Jan 2019

New medications provide better treatment for alcohol use disorders, chronic pain, mood disorders

Helping people with addictions has become a research passion for Purdue University's Richard van Rijn, who is leading a team to make drug discoveries to support millions around the world dealing with alcohol use disorders, chronic pain and mood disorders.

3 Jan 2019

Alzheimer’s Disease: Learning from the Past, Looking to the Future

An interview with Dr. Lloyd Tran, discussing the major barriers to Alzheimer’s research and development over the past 40 years.

From Alzheimer International Society 3 Jan 2019

New collaborative partnership in quest of novel antibiotics

The Global Antibiotic Research and Development Partnership, Eisai Co., Ltd. and Takeda Pharmaceutical Company Limited have signed an agreement for GARDP to access and screen components of Eisai and Takeda's chemical libraries.

12 Dec 2018

Newly developed molecules may provide more reliable relief for people with autoimmune diseases

Living with an autoimmune disease can feel like an insider is attacking your body. An estimated 24 million people in the United States are affected by autoimmune diseases, a group of diseases in which a person's immune system attacks part of the person's own body.

7 Dec 2018

Researchers identify powerful inhibitor of epigenetic factors that promote acute myeloid leukemia

Some severe forms of leukemia develop because proteins on the epigenetic level lose their regulative function. Now, in a broad international collaboration, UK researchers have identified molecules that can effectively inhibit the dysregulated proteins.

27 Nov 2018

UH pharmaceutical scientist developing new drug to treat children with rare genetic disorder

A University of Houston pharmaceutical scientist is developing a new drug which could bring relief to children suffering with Familial Adenomatous Polyposis, a rare genetic disorder characterized by hundreds - if not thousands - of colorectal polyps.

21 Nov 2018

Scientists develop new method to produce irradiated nanomaterials for medical applications

Under the leadership of Petr Cígler from the Institute of Organic Chemistry and Biochemistry and Martin Hrubý from the Institute of Macromolecular Chemistry, both of which are part of the Czech Academy of Sciences, a team of researchers has developed a revolutionary method for the easy and inexpensive production of irradiated nanodiamonds and other nanomaterials suitable for use in highly sensitive diagnostics of diseases, including various types of cancer.

12 Nov 2018

US businessman offers $5 million to UTSA College to incubate Alzheimer's challenge

To expand the understanding and explanation of Alzheimer's disease, United States businessman James Truchard has given a $5 million USD gift to The University of Texas at San Antonio College of Sciences to establish the Oskar Fischer Project.

5 Nov 2018

Battling against resistant and sensitive types of influenza A

Another flu season is here, which means another chance for viruses to mutate. Already, most influenza A viruses contain a mutation that confers resistance against one class of antiviral medications, and the bugs are steadily gaining resistance against another class.

25 Oct 2018

Cancer cells hijack communication between fallopian tube and ovary to drive tumor growth

New research from the University of Illinois at Chicago shows that cancer cells in the fallopian tube affect normal chemical signaling between reproductive tissues and stimulate the release of norepinephrine, a small molecule hormone, from the ovary.

10 Oct 2018

Arcus Biosciences announces presentation of final results from Phase 1 study of AB928 at ESMO 2018

Arcus Biosciences, Inc., a clinical-stage biopharmaceutical company focused on creating innovative cancer immunotherapies, today announced that it will present final results from the Phase 1 study of AB928, its dual adenosine receptor antagonist, in healthy volunteers during a poster display session at the European Society of Medical Oncology 2018 Congress, being held October 19-23, 2018, in Munich, Germany.

8 Oct 2018

National Institutes of Health supports novel drug discovery research

Approximately $1.7 million in new funding from the National Institutes of Health will enable a multidisciplinary team of University of Illinois at Chicago researchers to build a reference library of bacteria to help scientists quickly identify bacterial strains and analyze their disease-fighting potential.

5 Oct 2018

Stevens researchers develop new class of molecules for breast cancer treatment

Researchers at Stevens Institute of Technology and colleagues have designed and developed a new class of molecules that use a never-before-known mechanism that may halt or destroy breast cancer tumors, particularly for patients with drug-resistant or dangerously metastatic stages of the disease.

4 Oct 2018