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Bird flu in humans highlights vulnerability of people to emerging diseases

The occurrence of avian influenza in humans is a reminder of the vulnerability of people to an emerging pandemic, Mayo Clinic researchers warn in the current issue of Mayo Clinic Proceedings.

13 Apr 2004

Gene therapy helps damaged heart cells regain strength and beat normally

Researchers at Jefferson Medical College and Duke University have used gene therapy to help damaged heart cells regain strength and beat normally again in the laboratory. The work takes the scientists one step closer to eventual clinical trials in humans.

12 Apr 2004

Extended lymph node dissection, a treatment for gastric cancer

Extended lymph node dissection – a treatment for gastric cancer involving the surgical removal of lymph nodes near the tumor, in distant areas of the stomach, and in some cases, in combination with the removal of the spleen and pancreas tail – has shown no long-term survival benefit for gastric cancer patients

12 Apr 2004

Computerized entry systems may have limited impact on patient harm

Computerized prescriber order entry (CPOE) systems decrease medication error, but they may not decrease patient harm due to medication error, according to the results of a study conducted at Northwestern Memorial Hospital and published this week in Archives of Internal Medicine.

12 Apr 2004

Screening for alcohol problems in hospitals needs improvement

Many people admitted to hospitals in the U.S. have alcohol use disorders that go undetected, according to a new study by scientists at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), one of the National Institutes of Health (NIH).

12 Apr 2004

Surprises found In gene variation associated with schizophrenia

Approximately two percent of Caucasians have a gene segment variation that can cause a certain form of schizophrenia. Most people with the variation, known as a polymorphism, do not have the disease. A University of Iowa Health Care study reveals a good prognosis for people who do have this form of schizophrenia.

12 Apr 2004

Continuous insulin monitoring does not raise hospital costs

Patients with diabetes whose glucose is continually monitored after coronary bypass artery graft surgery do not incur higher medical costs despite the additional testing, Penn State Diabetes Center researchers report.

12 Apr 2004

Kentucky's first robotic procedure treats prostate

Earlier this year, the University of Kentucky Hospital was the first hospital in Kentucky to perform a minimally invasive, coronary artery bypass graft using surgical robotic instruments.

12 Apr 2004

Teens are obese due to lack of exercise

The American Council on Exercise (ACE), America's nonprofit fitness advocate, today applauds the recent findings by University of California San Diego School of Medicine and San Diego State University researchers stating that the lack of physical activity was the most significant obesity risk factor contributing to obesity in 11- to 15-year-olds.

12 Apr 2004

Process to minimize the side effect of painful arthritis

The University of Missouri Friday announced the discovery of a process to minimize the side effect of painful arthritis that develop after knee surgeries. The procedure will be tested in human clinical trials this summer if the process is approved by the Food and Drug Administration, the Columbia, Mo-based school said.

12 Apr 2004

AMA tackles health literacy

An estimated 90 million adults – nearly half the adults in America – have trouble understanding medical terms and directions, according to two studies published on April 8 by the Institute of Medicine (IOM) and the Agency for Healthcare Research and Quality (AHRQ).

12 Apr 2004

Hepatitis C wonder drug Ribasphere gets approval from FDA

The President and CEO of Three Rivers Pharmaceuticals, Donald J. Kerrish, RPh., stated, “The approval of Ribasphere™ marks a milestone in the treatment of HCV. Ribasphere™ is positioned to break down the economic barriers that have existed for the past decade in treating this chronic and potentially deadly disease.” Traditionally the cost of treatment for HCV can range from $20,000 – $25,000 annually. “Our aim is to bring affordable medicine to all individuals infected with this dreadful disease.” Mr. Kerrish continued.

8 Apr 2004

University of Florida researchers have used a common gel to successfully deliver gene therapy to the diaphragm

The technique, described in the current issue of Molecular Therapy, could eventually lead to a method to correct genetic conditions in humans that cause diaphragm weakness and respiratory failure -- a leading cause of death in tens of thousands of patients with forms of muscular dystrophy, including Pompe’s disease. Thousands of Americans with muscle-weakening diseases are placed on ventilators each year, according to the Muscular Dystrophy Association.

7 Apr 2004

Cinacalet helps control overactive thyroids, a major complication of advanced kidney disease

A new drug can help control an overactive thyroid, a major complication of advanced kidney disease, by playing a trick on the gland, a new study finds. The drug, cinacalet, is much more effective at keeping the parathyroid gland working normally than a placebo, according to the study. It may be a good alternative to standard therapy, researchers said.

7 Apr 2004

Intensive diabetes management yields positive results

Increasing diabetes awareness and integrating a multi-faceted, approach to improve patient care and education, results in significantly improved patient outcomes, according to a report in the April issue of Clinical Diabetes, a publication of the American Diabetes Association.

7 Apr 2004

Protein kinase complex influences the outer layer of skin to control the eventual shape of the full-grown skeleton and skull

Continuing studies about an important regulatory protein kinase complex called I-kappa-B kinase (or IKK) have now shown that a subunit of IKK – IKK alpha – influences the outer layer of skin in developing mice to control the eventual shape of the full-grown skeleton and skull.

7 Apr 2004

Molecular analyses of leukemia patients suggest strategies for better treatments

The cure rate for pediatric acute lymphoblastic leukemia (ALL) might continue to rise with improved use of conventional therapies. But even more effective and less toxic therapies based on genetic and pharmacogenetic studies might one day push the success rate close to 100 percent, according to an article published by investigators at St. Jude Children’s Research Hospital in the April 8 issue of the New England Journal of Medicine.

7 Apr 2004

Research shows that intense high dose cholesterol lowering drugs result in a major reduction in deaths and severe heart attacks

If you want to increase your chances of living longer, taking cholesterol drugs is an easy way to do it. That's the message from a Harvard study of 4,162 people hospitalized in 350 places in eight countries. It is the first research to show that intense lowering of cholesterol results in a major reduction in deaths and severe heart attacks.

7 Apr 2004

Time-reversal acoustics research promises medical breakthroughs

Scientists have not yet found a way to actually make time run backward, but in the cutting-edge world of recent acoustics research, they have shown a way to make sound waves run backward in a kind of ultra-focused reverse echo. By the technology known as time-reversal acoustics, sound waves - in exact reverse order from the original sound - echo directly and very precisely back to their source point.

7 Apr 2004

Women with a history of pre-eclampsia are at increased risk of cancer

Women with a history of pre-eclampsia are at increased risk of cancer, particularly cancers of the stomach, breast, ovary, lung and larynx, according to a Columbia University study recently published by the British Medical Journal. Researchers studied 37,000 women in western Jerusalem, Israel, who delivered babies in three large hospitals between 1964 and 1976.

7 Apr 2004