Metabolic Disease News and Research

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Dietary polyphenol intake reduces risk of metabolic syndrome

Researchers investigate the relationship between dietary polyphenol intake and metabolic syndrome.

10 Mar 2023

Additive effects of genetic, socioeconomic factors account for the prevalence of type 2 diabetes and obesity

New research led by investigators at Massachusetts General Hospital, a founding member of Mass General Brigham, indicates that socioeconomic and genetic factors likely interact in an additive way to affect people's risks of developing obesity and type 2 diabetes.

7 Mar 2023

Research helps explain the metabolic differences of people living at high altitudes

Compared to those of us who live at sea level, the 2 million people worldwide who live above 4,500 meters (or 14,764 feet) of elevation-;about the height of Mount Rainier, Mount Whitney, and many Colorado and Alaska peaks-;have lower rates of metabolic diseases such as diabetes, coronary artery disease, hypercholesterolemia, and obesity.

7 Mar 2023

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

MK-0616, an experimental oral proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, met its primary endpoint and substantially reduced levels of low-density lipoprotein (LDL) cholesterol in people with high cholesterol and/or heart disease related to clogged arteries, in a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Adding evidence to the weight gain causality of sugary drinks

The review, published in the American Journal of Clinical Nutrition, is the most extensive analysis to date of research on sweetened drinks and overweight and obesity -; both of which heighten risks for diabetes, heart disease, some cancers, and other diseases.

2 Mar 2023

Reduced butyrate production in the microbiome of type 2 diabetics

Researchers observe reduced levels of butyrate-producing bacteria in the microbiome of type 2 diabetics.

15 Feb 2023

Increased risk of developing metabolic conditions during COVID-19 pandemic

Researchers examine the prevalence of metabolic conditions with health and sociodemographic factors during the COVID-19 pandemic.

14 Feb 2023

High prevalence and risks of heart failure warrant urgent action, say researchers

Up to 2% of adults in Europe, North America, and Israel likely have heart failure, and are at high risk of death and additional serious complications, suggest current estimates based on digital health records for 11 countries, and published online in the journal Heart.

14 Feb 2023

Can lifestyle and nutrition be the answer for metabolic syndrome and type 2 diabetes remission?

Recently, scientists have reviewed the existing literature to elucidate the root cause of metabolic syndrome and type 2 diabetes.

10 Feb 2023

Metabolically unhealthy people may be at increased risk of obesity-related cancer

For up to 40 years, nearly 800,000 people from Sweden, Norway and Austria have been tracked based on how their BMI and metabolic health - that is, their blood pressure, blood glucose levels and blood fats - affect the risk of suffering from obesity-related cancers.

7 Feb 2023

The relationship between metabolic disease and alternations in lipid homeostasis

Researchers assessed the function of lipids in metabolic diseases.

4 Jan 2023

Exposure to blue-green algae toxin shown to wreak havoc on gut bacteria and cause liver damage

Exposure to a specific type of blue-green algae toxin known as cylindrospermopsin has shown to wreak havoc on gut bacteria and an increased probability of irritable bowel syndrome, inflammatory bowel disease, celiac disease, type 1 diabetes, obesity and inflammation of the liver – a precursor to liver cancer – according to a study led by the University of California, Irvine.

20 Dec 2022

Many genetic disorders respond well to specialized gene therapy

When the normal DNA sequence in an individual changes or mutates it can cause disease. The mutation may involve multiple genes and may be caused by environmental factors, or there may be chromosomal defects that are harmful at birth, in infancy or environment at a later stage.

12 Dec 2022

Consistent exercise linked to beneficial epigenetic changes, twin-study shows

Consistent exercise can change not just waistlines but the very molecules in the human body that influence how genes behave, a new study of twins indicates.

6 Dec 2022

Gut microbial flavonoid catabolite reverses fatty liver disease in mice

Researchers report that a gut microbial catabolite could reduce the cardiometabolic disease burden in mice.

29 Nov 2022

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

In a recent study published in the journal Cell Reports, researchers in Cincinnati, USA, assessed the impact of dietary alteration to a high-fat diet (HFD) on the intestine.

17 Nov 2022

Environmental toxicants contribute to obesity and metabolic disease

In a recent study published in the Current Opinion in Pharmacology journal, researchers assessed the impact of environmental toxicants and brown adipose tissue (BAT) on obesity and metabolic disorders.

4 Nov 2022

Study highlights the importance of early screening of first-degree relatives of patients with NAFLD

Approximately one-fourth of the general population worldwide has nonalcoholic fatty liver disease, known as NAFLD, an umbrella term for a range of liver conditions affecting people who drink little to no alcohol. NAFLD can lead to cirrhosis, liver cancer and liver failure.

1 Nov 2022

Is maternal caffeine consumption associated with child growth, and are such associations present in low-consumption groups?

A new paper published in JAMA Network Open discusses the relationship between caffeine consumption in pregnancy and the future growth of the offspring.