Metabolic Disease News and Research

RSS

CN Bio PhysioMimix Organ-on-a-Chip data supports Inipharm’s INI-822 for metabolic liver disease treatment now in clinical testing

CN Bio today announced its PhysioMimix® assay for Non-alcoholic steatohepatitis (NASH).

From CN-Bio 4 Dec 2023

High dietary insulin index associated with increased risk of metabolic unhealthiness, research show

Study explored the association between dietary insulin index (DII) and dietary insulin load (DIL) with metabolic healthy (MH) status and the serum levels of brain-derived neurotrophic factor (BDNF) and adropin among the Iranian adult population.

24 Nov 2023

Study reveals surprising trends in non-diabetic adults' use of artificial sweeteners in Brazil

The study investigates the widespread use of non-nutritive sweeteners (NNS) among non-diabetic Brazilian adults, revealing that higher education, income, and BMI increase the likelihood of regular NNS consumption, challenging the perception of NNS as a healthy alternative.

19 Nov 2023

New calculator estimates a person’s cardiovascular disease risk over the next 30 years

A new calculator estimates a person's risk for cardiovascular disease (CVD) over the next 30 years by combining measures of cardiovascular, kidney and metabolic health for the first time, according to a new American Heart Association Scientific Statement published today in the Association's flagship journal Circulation.

10 Nov 2023

Study shows link between food insecurity and liver disease in teens

Teens from low-income families experiencing food insecurity are developing the most common form of liver disease twice as often as those who have easier access to food, likely because they rely on low-cost, ultra-processed foods, according to a study scheduled for presentation at The Liver Meeting, held by the American Association for the Study of Liver Diseases.

7 Nov 2023

Researchers receive $3.6 million to test novel diagnosis and treatment combination for diabetic neuropathy

...

24 Oct 2023

Mucin glycosylation plays crucial role in protecting against obesity and intestinal inflammation

Located in the mucus layer that lines the gastrointestinal tract, mucins-;proteins with attached sugar molecules-;play a key role in combating bacterial infection and providing a safe haven to friendly gut bacteria through unknown mechanisms.

11 Oct 2023

Presidential advisory by the American Heart Association: connecting cardiovascular, kidney, and metabolic health

The interplay among chronic kidney disease, metabolic risk factors, and the cardiovascular system.

11 Oct 2023

Health experts redefine cardiovascular disease risk, prevention and management

Health experts are redefining cardiovascular disease (CVD) risk, prevention and management, according to a new American Heart Association presidential advisory published today in the Association's flagship journal Circulation.

9 Oct 2023

Study reveals key driver of metabolic rewiring in liver cancer cells

Cancer cells are chameleons. They completely change their metabolism to grow continuously. University of Basel scientists have discovered that high levels of the amino acid arginine drive metabolic reprogramming to promote tumor growth.

6 Oct 2023

Universal screening: A game-changer in early detection and management of type 1 diabetes

Dr. Emily K. Sims discusses the crucial role of universal type 1 diabetes (T1D) screening in early detection, especially in individuals without a family history, at the EASD Annual Meeting. This proactive approach, aligned with disease-modifying therapies, aims to prevent severe diabetic ketoacidosis episodes, marking a stride towards better management of T1D.

3 Oct 2023

Could plant-based phytonutrients be the secret weapon against obesity?

This comprehensive review in the journal Foods explores the therapeutic potential of phytonutrients in combating obesity. The paper delves into various plant-based compounds like polyphenols, alkaloids, and terpenoids, detailing their mechanisms of action in inhibiting fat accumulation, regulating metabolism, and even altering gut microbiota.

1 Oct 2023

Genetic markers could help identify people at risk for metabolic dysfunction-associated steatotic liver disease

An astounding 30% of Americans currently have metabolic dysfunction-associated steatotic liver disease, or MASLD, which is formerly known as nonalcoholic fatty liver disease, or NAFLD.

27 Sep 2023

The science of when you should exercise to beat obesity

A new paper in Obesity explores the diurnal relationship of obesity to MVPA – at what time does MVPA pay off the most in preventing obesity?

25 Sep 2023

How important is inflammation and body weight in the origin of depression?

A new paper in BMC Medicine examines the role of inflammation and body mass index (BMI) in the etiology of treatment-resistant depression.

18 Sep 2023

Genetics and diet shape insulin signaling in mice

Researchers have produced a comprehensive picture of insulin signalling in mice and suggest that it is shaped by entangled effects of genetics and diet.

13 Sep 2023

Theabrownin from dark tea may have the potential to treat insulin resistance

The effects of theabrownin (TB) from dark tea treatment on insulin resistance (IR).

8 Sep 2023

VAI scientists uncover mechanism that annotates genetic information passed from fathers to offspring

Van Andel Institute scientists and collaborators have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring.

7 Sep 2023

The potential of targeting mitochondria-associated programmed cell death for age-related disease treatment

The review summarized the involvement of mitochondria in age-related disease progression and highlighted its potential as a therapeutic target of these diseases.

28 Aug 2023

Scientists discover potential biomarkers linked to metastatic prostate cancer in Black men

Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, have identified a cell metabolism process found in men with diabetes and metastatic prostate cancer that could one day lead to improved testing and treatments for Black men with these diseases.

15 Aug 2023