Metabolic Disorders News and Research

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GLP-2 regulates appetite by influencing gut-brain communication and gastrointestinal motility

Researchers examine the role of GLP-2 in regulating food intake through its effects on gastrointestinal motility and satiety signals, offering insights into potential obesity treatments.

12 Sep 2024

TAAR1 gene: A new key to mental health

In the complex landscape of mental health research, a new peer-reviewed Viewpoint review sheds light on an underexplored genetic player: the trace amine-associated receptor 1 (TAAR1). Published in Genomic Psychiatry (ISSN: 2997-2388, Genomic Press, New York), this thought-provoking analysis suggests that mutations in the TAAR1 gene may be a crucial piece of the puzzle in understanding and treating neuropsychiatric disorders.

11 Sep 2024

High linoleic acid intake during pregnancy may harm fetal growth and raise obesity risk

High maternal linoleic acid intake during pregnancy may impact fetal development and increase the risk of obesity and inflammation in offspring. However, more research is needed to fully understand these effects in humans.

10 Sep 2024

Night owls have higher BMI, larger waists and face higher risk of type 2 diabetes

Night owls have a higher BMI, larger waists, more hidden body fat and are almost 50% more likely to develop type 2 diabetes (T2D) than those who go to bed earlier, new research to be presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September), has found.

9 Sep 2024

Weight-loss surgery offers better control of high blood pressure compared to medications

People with obesity who underwent weight-loss surgery were more likely to control their high blood pressure over a 1-to-5 year follow-period compared to those who managed their high blood pressure with medications and lifestyle management, according to preliminary research to be presented at the American Heart Association's Hypertension Scientific Sessions 2024.

5 Sep 2024

Elevated atherogenic index linked to higher erectile dysfunction risk

Study identifies a significant link between higher atherogenic index of plasma (AIP) levels and increased erectile dysfunction (ED) risk among US men, with implications for early intervention and cardiovascular health.

5 Sep 2024

Gut bacteria pathways directly linked to insomnia risk identified

Study uncovers a causal link between specific gut microbiome metabolic pathways and insomnia, highlighting potential therapeutic targets for improving sleep quality.

3 Sep 2024

Is semaglutide use during breastfeeding safe?

Researchers found no detectable levels of semaglutide in breast milk, suggesting minimal risk to breastfed infants, but highlighted the need for monitoring maternal nutrition and milk production.

2 Sep 2024

Fermented lingonberry juice shown to reduce inflammation and support gut health in IBD

Fermented lingonberry juice may help manage inflammatory bowel disease (IBD) by modulating both the oral and gut microbiomes, reducing inflammation, and promoting beneficial bacteria.

2 Sep 2024

16 promising postdoctoral scientists awarded Damon Runyon Fellowships for cancer research

The Damon Runyon Cancer Research Foundation has named 16 new Damon Runyon Fellows, exceptional postdoctoral scientists conducting basic and translational cancer research in the laboratories of leading senior investigators.

28 Aug 2024

New $400 million donation reinforces Columbia's leadership in biomedical science

Columbia University announced today a new $400 million gift from Roy and Diana Vagelos, which will secure Columbia's leadership in biomedical science research and education and produce a vast array of compelling opportunities for improving society's health and wellbeing.

22 Aug 2024

Processed and red meat intake associated with higher diabetes risk

Meat consumption, particularly consumption of processed meat and unprocessed red meat, is associated with a higher type 2 diabetes risk, an analysis of data from 1.97 million participants, published today in The Lancet Diabetes and Endocrinology, has found.

20 Aug 2024

How persistent organic pollutants affect gut health: findings on metabolic disruptions and microbiota changes

Early life exposure to potent AHR agonists on gut microbiota and its potential effects on metabolic health later in life.

20 Aug 2024

Obesity-induced adipose inflammation boosts extracellular vesicle secretion

New research from the University of Eastern Finland sheds light on the mechanisms associating obesity with inflammation by exploring tiny membrane particles, known as extracellular vesicles, secreted by human adipocytes.

19 Aug 2024

Gut microbiota plays a crucial role in type 2 diabetes management

Research reveals the intricate role of gut microbiota in type 2 diabetes, highlighting personalized therapeutic strategies and the complexity of microbial interactions with antidiabetic drugs.

15 Aug 2024

Early exposure to 'forever chemicals' alters gut microbiome and increases metabolic disease risk

Early life exposure to 'forever chemicals' in the environment permanently disrupts the gut microbiome in mice, contributing to the development of metabolic disease in later life, according to new research led by Penn State.

14 Aug 2024

Calorie restriction and therapy combo reshapes gut microbiome, boosts mental health in women

Study finds that combining caloric restriction with psychological interventions significantly alters the gut microbiome and improves stress-related mental health in women.

11 Aug 2024

Study identifies brain circuit that balances hunger-driven and pleasure-driven eating

People eat either because they are hungry or for pleasure, even in the absence of hunger. While hunger-driven eating is fundamental for survival, pleasure-driven feeding may accelerate the onset of obesity and associated metabolic disorders.

9 Aug 2024

Study reveals key brain cells help resist food temptations in favor of exercise

Hypocretin/orexin neurons (HONs) are crucial for resisting temptation and choosing exercise over highly palatable foods. This finding highlights potential targets for promoting physical activity and combating obesity.

7 Aug 2024

Brain chemical orexin plays key role in choosing exercise over treats

Should I go and exercise, or would I rather go to the café and enjoy a delectable strawberry milkshake? Until now, what exactly happens in our brain when we make this decision has been a mystery to science, but researchers at ETH Zurich have found the solution.

6 Aug 2024