Metabolic Disorders News and Research

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Research findings reveal new approach to prevent age-related obesity

The function and distribution of adipose tissue in the body change during the course of life. Beige fat cells, a special type of adipocytes, have the capability to use energy reserves - fatty deposits - by generating heat in a process known as thermogenesis.

4 May 2017

New research uncovers role of mysterious molecule in skin cancer

New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) at Lake Nona uncovers the modus operandi of a mysterious molecule called SPRIGHTLY that has been previously implicated in colorectal cancer, breast cancer, and melanoma.

3 May 2017

Study provides new insights on molecular mechanisms that impair muscle stem cells during aging

Researchers at Sanford Burnham Prebys Medical Discovery Institute have identified a previously unrecognized step in stem cell-mediated muscle regeneration.

26 Apr 2017

MGH researchers provide direct link between ‘leaky gut’ and chronic inflammatory disease

With the help of genetically engineered mice, scientists at the Massachusetts General Hospital are moving closer to establishing the role that increased intestinal permeability, sometimes called a "leaky gut," plays in chronic inflammatory conditions.

20 Apr 2017

Study establishes potential of BAT receptors as druggable targets for treatment of obesity, diabetes

According to research published online in The FASEB Journal, scientists have discovered a way to increase the amount of metabolism-boosting brown adipose tissue (BAT) ("good" fat) by employing two receptors on BAT cells as potential therapeutic targets.

17 Apr 2017

New initiative aims to study relationship between brain and obesity

The Naomi Berrie Diabetes Center at Columbia University Medical Center has launched an initiative to study the relationship between the brain and metabolic disorders such as obesity and diabetes.

5 Apr 2017

Low normalized grip strength linked to cardiometabolic diseases and disabilities in adults

A simple test to determine a person's grip strength may be a predictor of developing metabolic disorders in middle or older age, a new cross-continental study has found.

5 Apr 2017

Switching off glucocorticoid signaling in bone could protect against diet-induced metabolic disturbances

A high-calorie diet, even without a high amount of fat, causes bone loss, and both high-calorie and high-fat diets induce excessive fat gain and insulin resistance, a new study conducted in mice finds.

4 Apr 2017

Patent analysis reveals that saffron bioactives can be used to treat multiple disorders

Increased stress levels, sleep disorders and obesity have become hallmarks of present lifestyle. These conditions are often correlated with serious health problems such as cancer, diabetes, cerebral ischemia, stroke, etc.

27 Mar 2017

Circadian misalignments may favor diabetes development

Like almost all light-sensitive living beings, human beings follow biological rhythms set on a period of about 24 hours.

20 Mar 2017

Why don’t patients always discuss hyperglycemia with their doctor?

Hyperglycemia occurs when a patient has higher than normal blood sugar levels. If the levels are very high, consistently 13-14 or above, the patient will start to feel tired, thirsty and feel the urge to go to the toilet frequently to pass urine (micturition).

17 Mar 2017

Hormone secreted by bone cells can suppress appetite, mice study reveals

A hormone secreted by bone cells can suppress appetite, according to mouse studies conducted by Columbia University Medical Center researchers.

8 Mar 2017

Researchers develop new tool that quickly reveals metabolic fluxes in cells

If we were to take photographs at the underground stations in Barcelona, we would see the number of people waiting, find out what time the rush hour takes place and deduce why some stations are busier than others.

23 Feb 2017

Upstate opens new public cord blood bank in New York

Upstate Medical University opens the Upstate Cord Blood Bank, only the second public cord blood bank in New York and one of only 32 in the US.

20 Feb 2017

UT Southwestern scientists unravel role of PARP enzymes in major cellular activities

A component of an enzyme family linked to DNA repair, stress responses, and cancer also plays a role in enhancing or inhibiting major cellular activities under physiological conditions, new research shows.

16 Feb 2017

Estrogen regulates specific exosome-packed microRNAs in blood circulation, study shows

A study at the Gerontology Research Center demonstrated that, in blood circulation, the exosome-carried messenger molecule profile differs between post- and premenopausal women.

15 Feb 2017

Review shows lipid nanoparticles as highly promising delivery systems in gene therapy

Lipid nanoparticles (SLNs and NLCs) are regarded as highly promising systems for delivering nucleic acids in gene therapy.

14 Feb 2017

New study sheds light on how prenatal BPA exposure increases obesity risk

An expectant mother's exposure to the endocrine-disrupting chemical bisphenol A (BPA) can raise her offspring's risk of obesity by reducing sensitivity to a hormone responsible for controlling appetite, according to a mouse study published in the Endocrine Society's journal Endocrinology.

8 Feb 2017

FDA grants permission to market new Seeker System for screening rare metabolic disorders in newborns

The U.S. Food and Drug Administration today permitted marketing of the Seeker System for the screening of four, rare Lysosomal Storage Disorders (LSDs) in newborns.

3 Feb 2017

Non-invasive technique for examining fatty tissues could revolutionize medicinal drug testing

That's the hope of Associate Professor Noriyuki Yanaka and researchers at Hiroshima University who have developed a non-invasive way to assess the anti-inflammatory properties of fortified health foods and medications.

31 Jan 2017