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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Human exposure to glyphosate has increased significantly over 23 years, research finds

Analyzing samples from a prospective study, University of California San Diego School of Medicine researchers found that human exposure to glyphosate, a chemical widely found in weed killers, has increased approximately 500 percent since the introduction of genetically modified crops.

24 Oct 2017

Research shows role of federal drinking water regulations in reducing arsenic exposure

New research conducted at Columbia University's Mailman School of Public Health found that exposure to arsenic in drinking water was significantly reduced among Americans using public water systems following the Environmental Protection Agency regulation on maximum levels of arsenic.

23 Oct 2017

Serum metabolites linked to NAFLD may be heritable, research shows

Serum metabolites associated with nonalcoholic fatty liver disease may be heritable, according to research presented this week at The Liver Meeting - held by the American Association for the Study of Liver Diseases.

20 Oct 2017

Cholesterol byproduct acts on specific immune cells to facilitate breast cancer spread

High cholesterol levels have been associated with breast cancer spreading to other sites in the body, but doctors and researchers don't know the cause for the link.

12 Oct 2017

GW researcher awarded NIH grant to study how cocaine use affects HIV infection

Following studies showing that cocaine influences the replication and transcription of HIV, a researcher at the George Washington University School of Medicine and Health Sciences was awarded more than $2.3 million from the National Institutes of Health to look deeper into the involved molecular mechanisms that allow this effect to happen.

5 Oct 2017

UM SOM study finds intriguing relationship between sleep, cognition and kynurenine compound

More than 3.2 million Americans suffer from schizophrenia; about 100,000 people are newly diagnosed every year. The disease includes a wide range of symptoms including visual and auditory hallucinations, cognitive problems and motivational issues.

28 Sep 2017

Metabolic changes after quitting could help explain how ill-effects of smoking may be reversible

Even after years of smoking, the body has a remarkable ability to repair itself. Now in a study appearing in ACS' Journal of Proteome Research, scientists report that certain metabolic changes occur soon after quitting, and these changes could help explain how some ill-effects of smoking might be reversible.

21 Sep 2017

Research: The body's fat-metabolism causes detoxification of harmful substances from blood sugar

For several years, medical researchers, doctors, and dieticians have known that a low carbohydrate diet and plentiful fat can prevent a range of lifestyle and age-related diseases and thus promote healthy aging. But researchers from around the world have not been able to explain why this is the case.

18 Sep 2017

Phthalate levels in expectant fathers influence sperm epigenetics, study suggests

Early results from a larger, ongoing study led by environmental health scientist Richard Pilsner at the University of Massachusetts Amherst suggest that phthalate levels in expectant fathers have an effect on couples' reproductive success via epigenetic modifications of sperm DNA.

12 Sep 2017

New vaccine could offer protection against opioid combinations

Substance abuse is a continuing problem in the U.S., particularly with heroin and other opioids, to the point of being an epidemic.

21 Aug 2017

Research shows how glutamine plays role in regulating cellular differentiation programs

The 200 different types of cells in the body all start with the same DNA genome. To differentiate into families of bone cells, muscle cells, blood cells, neurons and the rest, differing gene programs have to be turned on or off.

17 Aug 2017

Researchers demonstrate potential of new PET tracer for imaging prostate cancer

In the featured translational article in the August issue of The Journal of Nuclear Medicine, researchers at the University of Michigan demonstrate the potential of a new PET tracer, Carbon-11 labeled sarcosine (11C-sarcosine), for imaging prostate cancer, and set the stage for its possible use in monitoring other cancers.

7 Aug 2017

Compound derived from cannabis may alter blood levels of antiepileptic drugs

New research published in Epilepsia, a journal of the International League Against Epilepsy (ILAE), suggests that an investigational neurological treatment derived from cannabis may alter the blood levels of commonly used antiepileptic drugs.

7 Aug 2017

New study shows how gut microbes can prevent severe flu infections in mice

Microbes that live in the gut don't just digest food. They also have far-reaching effects on the immune system.

3 Aug 2017

Low vitamin D may affect recovery of injured corneas

Injury or disease in combination with too little vitamin D can be bad for the window to your eyes. The three-layer, transparent cornea at the front of the eyes focuses the light coming in. But its prominent position also puts it at risk for injury from an errant mascara wand or over-prodding finger or a car accident.

24 Jul 2017

Researchers explore how physical exercise affects brain metabolism

Numerous studies have shown that physical exercise seems beneficial in the prevention of cognitive impairment and dementia in old age. Now researchers at Goethe University Frankfurt have explored in one of the first studies worldwide how exercise affects brain metabolism.

21 Jul 2017

EPFL researchers identify social rank as determining factor for vulnerability to stress

Stress is a major risk factor for a range of psychopathologies. However, stress does not affect everyone equally: in the face of sustained adversity, some people develop depression symptoms while others adapt and remain resilient.

13 Jul 2017

Targeting acid metabolite reduces size and spread of breast cancer

It's a metabolite found in essentially all our cells that, like so many things, cancer overexpresses. Now scientists have shown that when they inhibit 20-HETE, it reduces both the size of a breast cancer tumor and its ability to spread to the lungs.

12 Jul 2017

$Promising target may open door to new therapies for preventing bone fractures in diabetes patients$

Promising target may open door to new therapies for preventing bone fractures in diabetes patients

Researchers at New York University College of Dentistry have described a new target that may open the door to developing therapies for preventing bone fractures in people with type 2 diabetes.

7 Jul 2017

Researchers identify key protein that helps trigger ketamine's rapid antidepressant effects

UT Southwestern Medical Center scientists have identified a key protein that helps trigger ketamine's rapid antidepressant effects in the brain, a crucial step to developing alternative treatments to the controversial drug being dispensed in a growing number of clinics across the country.

22 Jun 2017